Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Eduard A. M. Fleer"'
Autor:
Petra, Kaufmann-Kolle, Eduard A M, Fleer, Jochem, Kötting, Christine, Behnert, Clemens, Unger, Hansjorg, Eibl
Publikováno v:
Journal of liposome research. 4(3)
We describe the preparation of small unilamellar and multilamellar vesicles from hexadecylphosphocholine, cholesterol and 1,2-dipalmitoyl-sn-glycero-phosphoglycerol in the molar ratio 4/5/1. Particle size and chemical stability of two types of liposo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2beeb494fe6e2547914c9743fddba912
https://pubmed.ncbi.nlm.nih.gov/29052489
https://pubmed.ncbi.nlm.nih.gov/29052489
Publikováno v:
Journal of Experimental Therapeutics and Oncology. 3:185-193
Hexadecylphosphocholine and other etherlipid-derived substances show a pronounced antiproliferative activity on neoplastic cells and a broad spectrum of other biological effects on many cell types in vitro and in vivo. Though the precise molecular me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c9b4d086aa4d947b8367a555ef55a8d
https://doi.org/10.1046/j.1359-4117.2003.01094.x
https://doi.org/10.1046/j.1359-4117.2003.01094.x
Publikováno v:
Journal of Experimental Therapeutics and Oncology. 2:213-218
Hexadecylphosphocholine (HePC) is the first representative of the alkylphosphocholines (APC), a new group of biologically active compounds. HePC has pronounced antiproliferative effects on neoplastic cells in vitro and in vivo. The molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e2a2f3becadac3157cc4a8c28f7738
https://doi.org/10.1046/j.1359-4117.2002.01036.x
https://doi.org/10.1046/j.1359-4117.2002.01036.x
Publikováno v:
Journal of Experimental Therapeutics and Oncology. 2:85-92
Hexadecylphosphocholine (HePC) belongs to a new group of antineoplastic agents, the alkylphosphocholines (APC). HePC shows a broad spectrum of biological effects in various cells in vitro and in vivo. It has pronounced antiproliferative effects on ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e1c84c6b8b8aba88dc3b4664bf21448
https://doi.org/10.1046/j.1359-4117.2002.01014.x
https://doi.org/10.1046/j.1359-4117.2002.01014.x
Publikováno v:
European Journal of Cancer. 37:503-511
Hexadecylphosphocholine (HePC) is the first representative of the alkylphosphocholines, a novel group derived from the cytotoxic etherlysophospholipids. HePC shows a broad spectrum of antiproliferative effects in neoplastic cells in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925e8023daf9b6dbd7b0f4385d3ab0b5
https://doi.org/10.1016/s0959-8049(00)00394-4
https://doi.org/10.1016/s0959-8049(00)00394-4
Publikováno v:
European Journal of Cancer. 33:1875-1880
Hexadecylphosphocholine (HePC) is a new etherphospholipid derived substance with pronounced antineoplastic activity. So far the mode of action of this compound has not been resolved. Therefore, we decided to approach this problem by generating HePC r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337ae3576c09c2c46b0580604785780d
https://doi.org/10.1016/s0959-8049(97)00234-7
https://doi.org/10.1016/s0959-8049(97)00234-7
Publikováno v:
European Journal of Cancer. 31:2080-2085
Hexadecylphosphocholine (HePC) is an analogue of the antiproliferative alkyllysophospholipids (ALP). As these lipid-like compounds interfere with membrane lipid metabolism at several sites, we studied the effects of HePC on uptake and metabolism of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b9d7d14f9d215b52adcb074c9c06e7
https://doi.org/10.1016/0959-8049(95)00350-9
https://doi.org/10.1016/0959-8049(95)00350-9
Publikováno v:
European Journal of Cancer. 30:509-515
We investigated the hypothesis that the antiproliferative effect of hexadecylphosphocholine (HePC) and 1- O -octadecyl-2- O -methyl-rac-glycero-3-phosphocholine (ET-18-OCH 3 ) is mediated through the inhibition of cellular protein kinase C (PKC). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf7ec7eb38bcf422e2ffe41ef48fa89
https://doi.org/10.1016/0959-8049(94)90428-6
https://doi.org/10.1016/0959-8049(94)90428-6
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1125:166-170
The substrate requirement of phospholipids for hydrolysis with phospholipase C from Bacillus cereus was studied with synthetic lipids well-defined in structure and configuration. For optimal activity, the glycerol molecule must contain three substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a813021fdbd45087b932a5e43c4cdad6
https://doi.org/10.1016/0005-2760(92)90041-s
https://doi.org/10.1016/0005-2760(92)90041-s