Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Edson X. Albuquerque"'
Autor:
Roger J. Mullins, Su Xu, Jiachen Zhuo, Steve Roys, Edna F.R. Pereira, Edson X. Albuquerque, Rao P. Gullapalli
Publikováno v:
Brain Sciences, Vol 10, Iss 6, p 365 (2020)
This study used in vivo magnetic resonance imaging (MRI) to identify age dependent brain structural characteristics in Dunkin Hartley guinea pigs. Anatomical T2-weighted images, diffusion kurtosis (DKI) imaging, and T2 relaxometry measures were acqui
Externí odkaz:
https://doaj.org/article/e4e12045d704464eb4148d9910d8f442
Autor:
Megan E. Shrieves, Joshua Chiappelli, William P. Fawcett, Edson X. Albuquerque, Britta Hahn, Marie B Yuille, Cory K Olmstead, Edna F. R. Pereira
Publikováno v:
Psychopharmacology
Rationale Cognitive benefits of nicotinic acetylcholine receptor (nAChR) agonists are well established but have generally been of small magnitude and uncertain clinical significance. A way of raising the effect size may be to facilitate agonist-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2917eb03af7a6bc2b4589c0630c976f
http://europepmc.org/articles/PMC6952331
http://europepmc.org/articles/PMC6952331
Autor:
Jiachen Zhuo, Edna F. R. Pereira, Roger J. Mullins, Edson X. Albuquerque, Rao P. Gullapalli, Su Xu, Steve Roys
Publikováno v:
Brain Sciences
Brain Sciences, Vol 10, Iss 365, p 365 (2020)
Volume 10
Issue 6
Brain Sciences, Vol 10, Iss 365, p 365 (2020)
Volume 10
Issue 6
This study used in vivo magnetic resonance imaging (MRI) to identify age dependent brain structural characteristics in Dunkin Hartley guinea pigs. Anatomical T2-weighted images, diffusion kurtosis (DKI) imaging, and T2 relaxometry measures were acqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07438120879df4346ff63db1f4a620d
http://europepmc.org/articles/PMC7349860
http://europepmc.org/articles/PMC7349860
Autor:
Edna F. R. Pereira, William P. Fawcett, D'Arice Carter, Joseph D. Pescrille, Yasco Aracava, Malcolm V. Lane, G. William Basinger, Edson X. Albuquerque
Publikováno v:
J Pharmacol Exp Ther
Earlier reports suggested that galantamine, a drug approved to treat mild-to-moderate Alzheimer’s disease (AD), and other centrally acting reversible acetylcholinesterase (AChE) inhibitors can serve as adjunct pretreatments against poisoning by org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7001fb3eb6fde3924fcb47f099689e15
https://pubmed.ncbi.nlm.nih.gov/32759369
https://pubmed.ncbi.nlm.nih.gov/32759369
Autor:
D'Arice Carter, Joseph D. Pescrille, G. William Basinger, Edson X. Albuquerque, Malcolm V. Lane, William P. Fawcett, Edna F. R. Pereira, Yasco Aracava
The present study was designed to evaluate the effectiveness of galantamine administered orally as a pre-treatment to mitigate the acute toxicity of 4.0xLD50 soman in Cynomolgus monkeys post-treated with atropine, 2-PAM, and midazolam. Pharmacokineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067429e8d3d94b59889aeabb806d84f7
https://doi.org/10.1101/2020.02.03.932798
https://doi.org/10.1101/2020.02.03.932798
Autor:
Jacek Mamczarz, Edson X. Albuquerque, Edna F. R. Pereira, Eric W. Lumsden, William P. Fawcett, Roger J. Mullins, Richard D. Burke, Rao P. Gullapalli, William R. Randall, Spencer W. Todd
Publikováno v:
Journal of Neurochemistry. 142:162-177
Organophosphorus (OP) insecticides are pest-control agents heavily used worldwide. Unfortunately, they are also well known for the toxic effects that they can trigger in humans. Clinical manifestations of an acute exposure of humans to OP insecticide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea52ea852ae0b1d75bbeb54b92f30c5b
https://doi.org/10.1111/jnc.14077
https://doi.org/10.1111/jnc.14077
Autor:
Todd D. Gould, Lace M. Riggs, Edson X. Albuquerque, Scott M. Thompson, Jonathan Fischell, Panos Zanos, Edna F. R. Pereira, Yasco Aracava
Publikováno v:
Neuropsychopharmacology
Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) retains the rapid and sustained antidepressant-like actions of ketamine, but is spared its dissociative-like properties and abuse potential. While (2R,6R)-HNK is thought to exert its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ec4938e23ad7ab4b889ef29c8536b8
https://pubmed.ncbi.nlm.nih.gov/31216563
https://pubmed.ncbi.nlm.nih.gov/31216563
Autor:
Eric W, Lumsden, Timothy A, Troppoli, Scott J, Myers, Panos, Zanos, Yasco, Aracava, Jan, Kehr, Jacqueline, Lovett, Sukhan, Kim, Fu-Hua, Wang, Staffan, Schmidt, Carleigh E, Jenne, Peixiong, Yuan, Patrick J, Morris, Craig J, Thomas, Carlos A, Zarate, Ruin, Moaddel, Stephen F, Traynelis, Edna F R, Pereira, Scott M, Thompson, Edson X, Albuquerque, Todd D, Gould
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(11)
Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) is a putative fast-acting antidepressant candidate. Although inhibition of NMDA-type glutamate receptors (NMDARs) is one mechanism proposed to underlie ketamine’s antidepressant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fea4226be62928bc830a4f9eba57b32
https://pubmed.ncbi.nlm.nih.gov/30796190
https://pubmed.ncbi.nlm.nih.gov/30796190
Autor:
Edson X. Albuquerque, Jacek Mamczarz, Yasco Aracava, Edna F. R. Pereira, Spencer W. Todd, Eric W. Lumsden
Publikováno v:
Neuropharmacology
For over three-quarters of a century, organophosphorus (OP) insecticides have been ubiquitously used in agricultural, residential, and commercial settings and in public health programs to mitigate insect-borne diseases. Their broad-spectrum insectici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778d7b6ed2a037fa230d57aca1ccf1e5
https://doi.org/10.1016/j.neuropharm.2020.108271
https://doi.org/10.1016/j.neuropharm.2020.108271
Autor:
Craig J. Thomas, Manickavasagom Alkondon, Ruin Moaddel, Scott M. Thompson, Jonathan Fischell, Heather J. Pribut, Irving W. Wainer, Greg I. Elmer, Nagendra Singh, Patrick J. Morris, Yuhong Fang, Carlos A. Zarate, Todd D. Gould, Edson X. Albuquerque, Panos Zanos, Xi Ping Huang, Katina Sourou Sylvestre Dossou, Peixiong Yuan, Polymnia Georgiou, Cheryl L. Mayo
Publikováno v:
Nature
Major depressive disorder afflicts ~16 percent of the world population at some point in their lives. Despite a number of available monoaminergic-based antidepressants, most patients require many weeks, if not months, to respond to these treatments, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7710e443028054f967370064017ea8
http://europepmc.org/articles/PMC4922311
http://europepmc.org/articles/PMC4922311