The atypical β‐blocker S‐oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model

Autor: Luping Yuan, Jochen Springer, Sandra Palus, Silvia Busquets, Queralt Jové, Edson Alves de Lima Junior, Markus S. Anker, Stephan vonHaehling, Natalia Álvarez Ladrón, Oliver Millman, Annemijn Oosterlee, Agata Szymczyk, Francisco Javier López‐Soriano, Stefan D. Anker, Andrew J.S. Coats, Josep M. Argiles

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 653-660 (2023)

Abstract Background Beta‐blockers and selected stereoisomers of beta‐blockers, like bisoprolol and S‐pindolol (ACM‐001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of o

Externí odkaz: https://doaj.org/article/748d4538c7ce45089201c07ab020fbb6

Resposta do tratamento com metformina e do exercício físico aeróbio na mitigação dos distúrbios musculares induzidos pela doxorrubicina

Autor: Edson Alves de Lima Junior

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea697bbf58adaf71494c098dc00fcb84
https://doi.org/10.11606/t.42.2020.tde-06052021-153019

Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice

Autor: Tiego A. Diniz, José Cesar Rosa Neto, Jefferson Comin Jonco Aquino Júnior, Fábio Santos Lira, Edson Alves de Lima Junior, Francielle C. Mosele, Carolina Cabral-Santos, Alexandre Abilio de Souza Teixeira

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Made available in DSpace on 2019-10-06T15:36:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-07-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: Adiponectin exhibits anti-inflammatory actions and is mainly ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f972e81aee8378c1649f2749f68f2d4
https://doi.org/10.1016/j.cyto.2019.03.009

Macrophage immunophenotype but not anti-inflammatory profile is modulated by peroxisome proliferator-activated receptor gamma (PPARγ) in exercised obese mice

Autor: Loreana Sanches, Silveira, Luana Amorim, Biondo, Alexandre Abílio, de Souza Teixeira, Edson Alves, de Lima Junior, Angela, Castoldi, Niels Olsen Saraiva, Câmara, Willian T, Festuccia, José Cesar, Rosa-Neto, Fábio Santos, Lira

Publikováno v: Exercise immunology review. 26

Moderate aerobic training may be therapeutic for chronic low-grade inflammatory diseases due to the associated anti-inflammatory response that is mediated by immune cells. The peroxisome proliferator-activated receptor gamma (PPARγ) regulates the M1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3cf00a336d38e51d231bc8f4df2a834a
https://pubmed.ncbi.nlm.nih.gov/32139355

Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle

Autor: Edson Alves de Lima Junior, Gustavo D. Pimentel, Luís G O de Sousa, José Cesar Rosa Neto, Cinara L. Gonçalves, Ronaldo Vagner Thomatieli dos Santos, Fábio Santos Lira, Alex Shimura Yamashita, Emilio L. Streck

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle. 7:615-625

Background Cancer is considered the second leading cause of death in the world, and for the treatment of this disease, pharmacological intervention strategies are frequently based on chemotherapy. Doxorubicin (DOX) is one of the most widely used chem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::362f77c785234f8247992cc7662869c8
https://doi.org/10.1002/jcsm.12104