Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Edris Parsa"'
Autor:
Christopher B. Mulholland, Atsuya Nishiyama, Joel Ryan, Ryohei Nakamura, Merve Yiğit, Ivo M. Glück, Carina Trummer, Weihua Qin, Michael D. Bartoschek, Franziska R. Traube, Edris Parsa, Enes Ugur, Miha Modic, Aishwarya Acharya, Paul Stolz, Christoph Ziegenhain, Michael Wierer, Wolfgang Enard, Thomas Carell, Don C. Lamb, Hiroyuki Takeda, Makoto Nakanishi, Sebastian Bultmann, Heinrich Leonhardt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-24 (2020)
Active and passive demethylation pathways have been implicated in the genome-wide erasure of 5mC accompanying mammalian preimplantation development. Here the authors reveal a recently evolved, mammalian-specific pathway in which global hypomethylatio
Externí odkaz:
https://doaj.org/article/de4c9930854d459f81d5177982c48222
Autor:
Christopher B. Mulholland, Atsuya Nishiyama, Joel Ryan, Ryohei Nakamura, Merve Yiğit, Ivo M. Glück, Carina Trummer, Weihua Qin, Michael D. Bartoschek, Franziska R. Traube, Edris Parsa, Enes Ugur, Miha Modic, Aishwarya Acharya, Paul Stolz, Christoph Ziegenhain, Michael Wierer, Wolfgang Enard, Thomas Carell, Don C. Lamb, Hiroyuki Takeda, Makoto Nakanishi, Sebastian Bultmann, Heinrich Leonhardt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20453-0
Externí odkaz:
https://doaj.org/article/a9ee0759a31e47a58878982b9e6289ee
Autor:
Hiroyuki Takeda, Edris Parsa, Joel Ryan, Merve Yiğit, Wolfgang Enard, Carina Trummer, Christoph Ziegenhain, Michael D. Bartoschek, Ivo M. Glück, Franziska R. Traube, Don C. Lamb, Weihua Qin, Sebastian Bultmann, Christopher B. Mulholland, Aishwarya Acharya, Miha Modic, Thomas Carell, Michael Wierer, Heinrich Leonhardt, Enes Ugur, Ryohei Nakamura, Atsuya Nishiyama, Makoto Nakanishi, Paul Stolz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20453-0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10442699ddca49ddafcd6bdd3303056c
https://doi.org/10.1038/s41467-020-20453-0
https://doi.org/10.1038/s41467-020-20453-0
Autor:
Andriy Khobta, Thomas Carell, Edris Parsa, Nataliya Kitsera, Nadine Geier, Julia Allgayer, Martin Rossa
Publikováno v:
Nucleic Acids Research
Enzymatic oxidation of 5-methylcytosine (5-mC) in the CpG dinucleotides to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxycytosine (5-caC) has central role in the process of active DNA demethylation and epigenetic reprogramming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2188b66d6e6c6fc1117115e41ffb580
http://europepmc.org/articles/PMC5737506
http://europepmc.org/articles/PMC5737506
Publikováno v:
Organic Letters. 18:4368-4371
Investigation of the function of the new epigenetic bases requires the development of stabilized analogues that are stable during base excision repair (BER). Here we report the synthesis of 2'-(R)-fluorinated versions of the phosphoramidites of 5-met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8547502f05b9f50d1600d00ecf3e51
https://doi.org/10.1021/acs.orglett.6b02110
https://doi.org/10.1021/acs.orglett.6b02110
Autor:
Franziska R. Traube, Edris Parsa, Arne S. Schröder, Thomas Carell, Sascha Serdjukow, Katharina Iwan, Miriam Wallner
Publikováno v:
Chemical Communications. 52:14361-14364
A deeper investigation of the chemistry that occurs on the newly discovered epigenetic DNA bases 5-hydroxymethyl-(hmdC), 5-formyl-(fdC), and 5-carboxy-deoxycytidine (cadC) requires chemical tool compounds, which are able to dissect the different pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9b0175098a22e91e5b03684e35422e
https://doi.org/10.1039/c6cc07517g
https://doi.org/10.1039/c6cc07517g
Autor:
Ivo M. Glück, Hiroyuki Takeda, Carina Trummer, Michael D. Bartoschek, Merve Yiğit, Michael Wierer, Makoto Nakanashi, Sebastian Bultmann, Christopher B. Mulholland, Atsuya Nishiyama, Joel Ryan, Aishwarya Acharya, Don C. Lamb, Christoph Ziegenhain, Thomas Carell, Franziska R. Traube, Edris Parsa, Weihua Qin, Ryohei Nakamura, Heinrich Leonhardt, Enes Ugur, Miha Modic, Wolfgang Enard, Paul Stolz
Genome-wide DNA demethylation is a unique feature of mammalian development and naïve pluripotent stem cells. So far, it was unclear how mammals specifically achieve global DNA hypomethylation, given the high conservation of the DNA (de-)methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4da45db0302d0f150b7f37a68afb393
https://doi.org/10.1101/321604
https://doi.org/10.1101/321604
Autor:
Christopher B. Mulholland, Thomas Carell, Sebastian Bultmann, Franziska R. Traube, Edris Parsa, Miha Modic, Joel Ryan, Eva-Maria Eckl, Michael D. Bartoschek, Paul Stolz, Maximillian Schoenung, Heinrich Leonhardt
The TET-oxidized cytosine derivatives, 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC), are considered DNA demethylation intermediates as well as stable epigenetic marks in mammals. We compared modified cytosine and enzyme levels in TET-kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f41e7681b819b7f2b99c6f8134381e
Publikováno v:
Journal of Organometallic Chemistry. 696:3415-3420
A convenient synthesis and the characterization of six new electronically and coordinatively unsaturated complexes of the formula [Ru2(CO)4(μ-H)(μ-PtBu2)(μ-L2)] (2b–g) (Ru Ru) is described exhibiting a close relation to the known [Ru2(CO)4(μ-H)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2791d6988b6f762dacab890589601604
https://doi.org/10.1016/j.jorganchem.2011.07.033
https://doi.org/10.1016/j.jorganchem.2011.07.033