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Breast milk MSCs upregulated β-cells PDX1, Ngn3, and PCNA expression via remodeling ER stress /inflammatory /apoptotic signaling pathways in type 1 diabetic rats.

Autor: Khamis T; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt; Laboratory of Biotechnology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt. Electronic address: Khamistarek13@gmail.com., Abdelalim AF; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt., Saeed AA; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt., Edress NM; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt., Nafea A; Department of Pediatrics, Faculty of Medicine, Zagazig University, 44519, Zagazig, Egypt., Ebian HF; Department of Clinical Pathology, Faculty of Medicine, Zagazig University, 44519, Zagazig, Egypt., Algendy R; Department of Milk Hygiene, Food Control Department, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt., Hendawy DM; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, 44511, Zagazig, Egypt., Arisha AH; Department of Animal Physiology and Biochemistry, Faculty of Veterinary Medicine, Badr University in Cairo (BUC), Badr City, Cairo, Egypt; Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt; Laboratory of Biotechnology, Faculty of Veterinary Medicine, Zagazig University, 44519, Zagazig, Egypt. Electronic address: vetahmedhamed@zu.edu.eg., Abdallah SH; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, 44511, Zagazig, Egypt.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2021 Aug 15; Vol. 905, pp. 174188. Date of Electronic Publication: 2021 May 15.

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Bone marrow mesenchymal stem cells expressing Neat-1, Hotair-1, miR-21, miR-644, and miR-144 subsided cyclophosphamide-induced ovarian insufficiency by remodeling the IGF-1–kisspeptin system, ovarian apoptosis, and angiogenesis.

Autor: Ahmed, Amany I.¹ (AUTHOR), Dowidar, Mohamed F.¹ (AUTHOR), Negm, Asmaa F.¹ (AUTHOR), Abdellatif, Hussein^2,3 (AUTHOR), Alanazi, Asma^4,5 (AUTHOR), Alassiri, Mohammed^5,6 (AUTHOR), Samy, Walaa⁷ (AUTHOR), Mekawy, Dina Mohamed^8,9 (AUTHOR), Abdelghany, Eman M. A.¹⁰ (AUTHOR), El-Naseery, Nesma I.¹¹ (AUTHOR), Ibrahem, Mohamed A.¹² (AUTHOR), Albadawi, Emad Ali¹³ (AUTHOR), Salah, Wed¹⁴ (AUTHOR), Eldesoqui, Mamdouh^15,16 (AUTHOR), Tîrziu, Emil¹⁷ (AUTHOR), Bucur, Iulia Maria¹⁷ (AUTHOR) Iulia.bucur@usvt.ro, Arisha, Ahmed Hamed^18,19 (AUTHOR) vetahmedhamed@zu.edu.eg, Khamis, Tarek²⁰ (AUTHOR) t.khamis@vet.zu.edu.eg

Publikováno v: Journal of Ovarian Research. 11/29/2024, Vol. 17 Issue 1, p1-21. 21p.

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Early intervention with breast milk mesenchymal stem cells attenuates the development of diabetic-induced testicular dysfunction via hypothalamic Kisspeptin/Kiss1r-GnRH/GnIH system in male rats.

Autor: Khamis T; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519 Zagazig, Egypt., Abdelalim AF; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519 Zagazig, Egypt., Abdallah SH; Department of Biochemistry, Faculty of Medicine, Zagazig University, 44519 Zagazig, Egypt., Saeed AA; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519 Zagazig, Egypt., Edress NM; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, 44519 Zagazig, Egypt., Arisha AH; Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, 44519 Zagazig, Egypt. Electronic address: vetahmedhamed@zu.edu.eg.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Jan 01; Vol. 1866 (1), pp. 165577. Date of Electronic Publication: 2019 Oct 28.

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Mesenchymal stromal cells modulate unfolded protein response and preserve β-cell mass in type 1 diabetes.

Autor: LIU, SIYUAN¹ (AUTHOR), ZHAO, YUAN¹ (AUTHOR), YU, YU¹ (AUTHOR), YE, DOU¹ (AUTHOR), WANG, QIAN¹ (AUTHOR), WANG, ZHAOYAN¹ (AUTHOR), LUAN, ZUO¹ (AUTHOR) luanzuo@aliyun.com

Publikováno v: Biocell. 2024, Vol. 48 Issue 7, p1115-1126. 12p.

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Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway.

Autor: Haiqi Gao¹, Yifan Zhou², Chundong Yu³, Guifa Wang¹, Wenwei Song¹, Zixu Zhang¹, Lu Lu¹, Meilan Xue¹, Hui Liang⁴ lianghuiyxb@163.com

Publikováno v: Iranian Journal of Basic Medical Sciences. Jan2024, Vol. 27 Issue 1, p31-38. 8p.

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Dietary alpha-lipoic acid boosts growth, immune-antioxidant traits, behavior, and transcriptomes of antioxidant, apoptosis, and immune-related genes to combat cold stress in Nile tilapia (Oreochromis niloticus).

Autor: Behairy, Amany, Ghetas, Hanan A., Abd-Allah, Noura A., El-Houseiny, Walaa, Arisha, Ahmed H., Metwally, Mohamed M. M., Elshafey, Basma A., Al-Sagheer, Adham A., Mohamed, Engy M. M.

Publikováno v: Aquaculture International; Aug2024, Vol. 32 Issue 4, p4061-4090, 30p

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Antidiabetic and Protective Effects of Ferula assa-foetida L. oleo Gum Resin Ethanolic Extract on the Testis of Streptozotocin-Induced Diabetic Rats: A Histopathological Study.

Autor: Asadollahi, Zahra, Mohammadpour, Ahmad Ali, latifi, Ebrahim, Nourani, Hossein

Publikováno v: Iranian Journal of Veterinary Science & Technology; 2024, Vol. 16 Issue 3, p56-66, 11p

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Breast milk mesenchymal stem cells abate cisplatin-induced cardiotoxicity in adult male albino rats via modulating the AMPK pathway.

Autor: Nageeb, Mahitab M.¹ (AUTHOR), Saadawy, Sara F.² (AUTHOR), Attia, Seba Hassan¹ (AUTHOR) SHAttia@medicine.zu.edu.eg

Publikováno v: Scientific Reports. 10/20/2022, Vol. 12 Issue 1, p1-13. 13p.

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Green Synthesized Zinc Oxide Nanoparticles Attenuate Acrylamide-Induced Cardiac Injury via Controlling Endoplasmic Reticulum Stress–Associated Apoptosis Through ATF3/CHOP/BCL2 Signaling in Rats.

Autor: Alosaimi, Manal, Abd-Elhakim, Yasmina M., Mohamed, Amany Abdel-Rahman, Metwally, Mohamed M. M., Khamis, Tarek, Alansari, Wafa S., Eskandrani, Areej A., Essawi, Walaa M., Awad, Marwa M., El-Shaer, Rehab A. A., Ibrahim, Sarah, Nassan, Mohamed A., Metwally, Aya Sh.

Publikováno v: Biological Trace Element Research; Jun2024, Vol. 202 Issue 6, p2657-2671, 15p

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Development of Approaches to Reducing the Effective Gonadotropin Dose in Treating Androgen Insufficiency in Male Rats with Type 1 Diabetes Mellitus.

Autor: Bakhtyukov, A. A.¹ (AUTHOR) bahtyukov@gmail.com, Morina, I. Yu.¹ (AUTHOR), Derkach, K. V.¹ (AUTHOR), Romanova, I. V.¹ (AUTHOR), Sorokoumov, V. N.^1,2 (AUTHOR), Shpakov, A. O.¹ (AUTHOR)

Publikováno v: Journal of Evolutionary Biochemistry & Physiology. Sep2022, Vol. 58 Issue 5, p1503-1513. 11p.

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