Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Edouard Lhomme"'
Autor:
Leonie M. Weskamm, Paulina Tarnow, Charlotte Harms, Melanie Huchon, Matthijs P. Raadsen, Monika Friedrich, Laura Rübenacker, Cordula Grüttner, Mariana G. Garcia, Till Koch, Stephan Becker, Gerd Sutter, Edouard Lhomme, Bart L. Haagmans, Anahita Fathi, Sandra M. Blois, Christine Dahlke, Laura Richert, Marylyn M. Addo
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110470- (2024)
Summary: Besides neutralizing antibodies, which are considered an important measure for vaccine immunogenicity, Fc-mediated antibody functions can contribute to antibody-mediated protection. They are strongly influenced by structural antibody propert
Externí odkaz:
https://doaj.org/article/608910de3c4f4ba4ae8af02bb275eee1
Autor:
Houreratou Barry, Edouard Lhomme, Mathieu Surénaud, Moumini Nouctara, Cynthia Robinson, Viki Bockstal, Innocent Valea, Serge Somda, Halidou Tinto, Nicolas Meda, Brian Greenwood, Rodolphe Thiébaut, Christine Lacabaratz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0011500 (2024)
BackgroundThe exposure to parasites may influence the immune response to vaccines in endemic African countries. In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, s
Externí odkaz:
https://doaj.org/article/94cbd370e29942e4bceb8c789a014f7a
The importance of appropriate selection of clinical endpoints in outpatient COVID-19 clinical trials
Autor:
Kristian Thorlund, Davey Smith, Christopher Linsell, Nicholas White, Christopher Butler, David Boulware, Judith Currier, Ofir Harari, Edouard Lhomme, Nathalie Strub-Wourgaft, Stacey Adam, Edward Mills
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-5 (2023)
Abstract Clinical trial endpoints must be carefully and intentionally selected so that the results of the trial can be used to inform policy- and decision-making. The relative importance of potential endpoints often depends on the stakeholder, with p
Externí odkaz:
https://doaj.org/article/66d021901bcc41f9a3dde635bf62b6b8
Autor:
Moses Badio, Edouard Lhomme, Mark Kieh, Abdoul Habib Beavogui, Stephen B. Kennedy, Seydou Doumbia, Bailah Leigh, Samba O. Sow, Alpha Diallo, Daniela Fusco, Matthew Kirchoff, Monique Termote, Renaud Vatrinet, Deborah Wentworth, Helène Esperou, H. Clifford Lane, Jerome Pierson, Deborah Watson-Jones, Céline Roy, Eric D’Ortenzio, Brian Greenwood, Genevieve Chêne, Laura Richert, James D. Neaton, Yazdan Yazdanpanah, the PREVAC study team
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and safe preventative vaccine.
Externí odkaz:
https://doaj.org/article/a164f3bab6ae47f8b2c9a625b606ebd6
Autor:
Alexandre Duvignaud, Edouard Lhomme, Thierry Pistone, Racha Onaisi, Rémi Sitta, Valérie Journot, Duc Nguyen, Nathan Peiffer-Smadja, Antoine Crémer, Stéphane Bouchet, Thomas Darnaud, Delphine Poitrenaud, Lionel Piroth, Christine Binquet, Jean-François Michel, Benjamin Lefèvre, David Lebeaux, Josselin Lebel, Julie Dupouy, Caroline Roussillon, Anne Gimbert, Linda Wittkop, Rodolphe Thiébaut, Joanna Orne-Gliemann, Jean-Philippe Joseph, Laura Richert, Xavier Anglaret, Denis Malvy, the COVERAGE study group
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Abstract Objectives To assess the efficacy of several repurposed drugs to prevent hospitalisation or death in patients aged 65 or more with recent symptomatic SARS-CoV-2 infection (COVID-19) and no criteria for hospitalisation. Trial design Phase III
Externí odkaz:
https://doaj.org/article/f09c7f006a924356be2d7eab55c2380e
Autor:
Edouard Lhomme, Camara Modet, Augustin Augier, Sylvain Faye, Tienhan Sandrine Dabakuyo-Yonli, Claire Levy-Marchal, Eric D’Ortenzio, Yazdan Yazdanpanah, Geneviève Chêne, Abdoul Habib Beavogui, Laura Richert, the PREVAC study team
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Enrolling participants in clinical trials can be challenging, especially with respect to prophylactic vaccine trials. The vaccination of study personnel in Ebola vaccine trials during the 2014–2016 epidemic played a crucial role
Externí odkaz:
https://doaj.org/article/60aa8cb110414ae9adf53ef2a16f49ad
Publikováno v:
International Journal of Infectious Diseases, Vol 74, Iss , Pp 83-96 (2018)
Objectives: For Ebola vaccine development, antibody response is a major endpoint although its determinants are not well known. We aimed to review Ebola vaccine studies and to assess factors associated with antibody response variability in humans. Met
Externí odkaz:
https://doaj.org/article/0f4d1fa7c70e4f47bd1c5116d640946f
Publikováno v:
Essachess, Vol 11, Iss 1(21), Pp 29-48 (2018)
This study describes the production and evaluation of an online video explaining health insurance functioning to university students in France. The video was produced by a multidisciplinary team following a design thinking approach. A qualitative eva
Externí odkaz:
https://doaj.org/article/7fff1505cfee4d6486c173f6460007a3
Autor:
Moses Badio, Edouard Lhomme, Mark Kieh, Abdoul Habib Beavogui, Stephen B. Kennedy, Seydou Doumbia, Bailah Leigh, Samba O. Sow, Alpha Diallo, Daniela Fusco, Matthew Kirchoff, Monique Termote, Renaud Vatrinet, Deborah Wentworth, Helène Esperou, H. Clifford Lane, Jerome Pierson, Deborah Watson-Jones, Céline Roy, Eric D’Ortenzio, Brian Greenwood, Genevieve Chêne, Laura Richer, James D. Neaton, Yazdan Yazdanpanah, the PREVAC study team
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/aadb849b128c404bad12aac1c3b28798
Autor:
Edouard Lhomme, Laura Richert, Zoe Moodie, Chloé Pasin, Spyros A Kalams, Cecilia Morgan, Steve Self, Stephen C De Rosa, Rodolphe Thiébaut
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152952 (2016)
Initial evaluation of a candidate vaccine against HIV includes an assessment of the vaccine's ability to generate immune responses. However, the dynamics of vaccine-induced immune responses are unclear. We hypothesized that the IFN-γ producing cytot
Externí odkaz:
https://doaj.org/article/90fc2b0530cb4f5ea640e9b8181f8f03