Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Edouard G Stanley"'
Autor:
Elvira Forte, Mirana Ramialison, Hieu T Nim, Madison Mara, Jacky Y Li, Rachel Cohn, Sandra L Daigle, Sarah Boyd, Edouard G Stanley, Andrew G Elefanty, John Travis Hinson, Mauro W Costa, Nadia A Rosenthal, Milena B Furtado
Publikováno v:
eLife, Vol 11 (2022)
Organ fibroblasts are essential components of homeostatic and diseased tissues. They participate in sculpting the extracellular matrix, sensing the microenvironment, and communicating with other resident cells. Recent studies have revealed transcript
Externí odkaz:
https://doaj.org/article/fdff1021c46d4d60aff391d8030addd1
Autor:
Shicheng Sun, Ali Motazedian, Jacky Y. Li, Kevin Wijanarko, Joe Jiang Zhu, Kothila Tharmarajah, Kathleen A. Strumila, Anton Shkaruta, L. Rayburn Nigos, Jacqueline V. Schiesser, Yi Yu, Paul J. Neeson, Elizabeth S. Ng, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Arterial endothelial cells (AECs) are the founder cells for intraembryonic haematopoiesis. Here, we report a method for the efficient generation of human haemogenic DLL4+ AECs from pluripotent stem cells (PSC). Time-series single-cell RNA-se
Externí odkaz:
https://doaj.org/article/6b789ce0af934d5d87158dc872de5c71
Autor:
Stephanie F Bellmaine, Dmitry A Ovchinnikov, David T Manallack, Claire E Cuddy, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Spencer J Williams, Martin Pera
Publikováno v:
eLife, Vol 6 (2017)
Genetic analysis has revealed that the dual specificity protein kinase DYRK1A has multiple roles in the development of the central nervous system. Increased DYRK1A gene dosage, such as occurs in Down syndrome, is known to affect neural progenitor cel
Externí odkaz:
https://doaj.org/article/64708b8f9f454c8ea234db5e3b8859a8
Autor:
Christophe M Raynaud, Najeeb Halabi, David A Elliott, Jennifer Pasquier, Andrew G Elefanty, Edouard G Stanley, Arash Rafii
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54524 (2013)
Mesenchymal progenitors or stromal cells have shown promise as a therapeutic strategy for a range of diseases including heart failure. In this context, we explored the growth and differentiation potential of mesenchymal progenitors (MPs) derived in v
Externí odkaz:
https://doaj.org/article/0f8d6f2e4bdf4764a1303b457b9df14b
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55530 (2013)
BACKGROUND: The production of human platelets from embryonic stem cells in a defined culture system is a prerequisite for the generation of platelets for therapeutic use. As an important step towards this goal, we report the differentiation of human
Externí odkaz:
https://doaj.org/article/7fd5d98ac91e4cf3a56634b376629a4f
Autor:
Andrew B J Prowse, Fenny Chong, David A Elliott, Andrew G Elefanty, Edouard G Stanley, Peter P Gray, Trent P Munro, Geoffrey W Osborne
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52214 (2012)
Human embryonic stem cell (hESC) derivatives show promise as viable cell therapy options for multiple disorders in different tissues. Recent advances in stem cell biology have lead to the reliable production and detailed molecular characterisation of
Externí odkaz:
https://doaj.org/article/9c33bcc235e34987917f4b0979d649ed
Autor:
Drew M Titmarsh, James E Hudson, Alejandro Hidalgo, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Justin J Cooper-White
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52405 (2012)
Timed exposure of pluripotent stem cell cultures to exogenous molecules is widely used to drive differentiation towards desired cell lineages. However, screening differentiation conditions in conventional static cultures can become impractical in lar
Externí odkaz:
https://doaj.org/article/279b89e1e8bc404d85a16eed3a872ae8
Autor:
Louie Ye, Robyn Mayberry, Camden Y Lo, Kara L Britt, Edouard G Stanley, Andrew G Elefanty, Caroline E Gargett
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21136 (2011)
BACKGROUND: Recent studies have identified stem/progenitor cells in human and mouse uterine epithelium, which are postulated to be responsible for tissue regeneration and proliferative disorders of human endometrium. These progenitor cells are though
Externí odkaz:
https://doaj.org/article/c49d54c8c7014be3a2210e55d76248e3
Autor:
Lloyd A Pereira, Michael S Wong, Sue Mei Lim, Alexandra Sides, Edouard G Stanley, Andrew G Elefanty
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28394 (2011)
Mixl1 is a homeodomain transcription factor required for mesoderm and endoderm patterning during mammalian embryogenesis. Despite its crucial function in development, co-factors that modulate the activity of Mixl1 remain poorly defined. Here we repor
Externí odkaz:
https://doaj.org/article/70bf5739252c432cb0310fb748e0f635
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10706 (2010)
BACKGROUND: Mesendoderm induction during embryonic stem cell (ESC) differentiation in vitro is stimulated by the Transforming Growth Factor and Wingless (Wnt) families of growth factors. PRINCIPAL FINDINGS: We identified the periods during which Bone
Externí odkaz:
https://doaj.org/article/87eb754a83ee4924baf6fdc9368e3698