Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Edouard C Nice"'
Autor:
Ping Jin, Jingwen Jiang, Li Zhou, Zhao Huang, Siyuan Qin, Hai‐Ning Chen, Liyuan Peng, Zhe Zhang, Bowen Li, Maochao Luo, Tingting Zhang, Hui Ming, Ning Ding, Lei Li, Na Xie, Wei Gao, Wei Zhang, Edouard C Nice, Yuquan Wei, Canhua Huang
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp n/a-n/a (2022)
Abstract Metformin, a well‐known antidiabetic drug, has been repurposed for cancer treatment; however, recently observed drug resistance and tumor metastasis have questioned its further application. Here, we found that long‐term metformin exposur
Externí odkaz:
https://doaj.org/article/21de7353346a45f899760eb85b44cfa8
Autor:
Zhe Zhang, Siyuan Qin, Yan Chen, Li Zhou, Mei Yang, Yongquan Tang, Jing Zuo, Jian Zhang, Atsushi Mizokami, Edouard C Nice, Hai‐Ning Chen, Canhua Huang, Xiawei Wei
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 2, Pp n/a-n/a (2022)
Abstract Entering a drug‐tolerant persister (DTP) state of cancer cells is a transient self‐adaptive mechanism by which a residual cell subpopulation accelerates tumor progression. Here, we identified the acquisition of a DTP phenotype in multidr
Externí odkaz:
https://doaj.org/article/fba468bc75374ae3a4016b9dc92a4961
Autor:
Xiaodian Zhang, Hailong Tian, Yang Chen, Baichuan Liang, Edouard C. Nice, Canhua Huang, Na Xie, Shaojiang Zheng
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Immunotherapy has shown marked progress in promoting systemic anti-colorectal cancer (CRC) clinical effects. For further effectively sensitizing CRC to immunotherapy, we have engineered a pH-sensitive zeolitic imidazolate framework-8 (CS/NPs
Externí odkaz:
https://doaj.org/article/c680ef09da4d46f4a74a0ba001838a51
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 3, Pp 264-274 (2024)
Objective: To elucidate the biological basis of the heart qi deficiency (HQD) pattern, an in-depth understanding of which is essential for improving clinical herbal therapy. Methods: We predicted and characterized HQD pattern genes using the new stra
Externí odkaz:
https://doaj.org/article/12d9c5f4c0ec4227978edfb7d8832135
Autor:
Ke Ding, Hailong Tian, Lei Li, Zhihan Wang, Shanshan Liu, Ning Ding, Edouard C. Nice, Canhua Huang, Jinku Bao, Wei Gao, Zheng Shi
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Multi-modal combination therapy is regarded as a promising approach to cancer treatment. Combining chemotherapy and phototherapy is an essential multi-modal combination therapy endeavor. Ivermectin (IVM) is a potent antiparasitic agent ident
Externí odkaz:
https://doaj.org/article/997f8299cf494be7a38ed6900608136b
Autor:
Yuan-Yuan Zhang, Na Xie, Xiao-Dong Sun, Edouard C. Nice, Yih-Cherng Liou, Canhua Huang, Huili Zhu, Zhisen Shen
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-30 (2024)
Abstract Osteoporosis, a metabolic bone disease characterized by low bone mineral density and deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures worldwide. Accumulating evidence has revealed that sexual di
Externí odkaz:
https://doaj.org/article/e4b888aa2b1643eea7d03ded3d55d299
Autor:
Seong Beom Ahn, Charles Chan, Owen F Dent, Abidali Mohamedali, Sun Young Kwun, Candice Clarke, Julie Fletcher, Pierre H Chapuis, Edouard C Nice, Mark S Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117786 (2015)
Urokinase plasminogen activator receptor (uPAR) has been proposed as a potential prognostic factor for colorectal cancer (CRC) patient survival. However, CRC uPAR expression remains controversial, especially regarding cell types where uPAR is overexp
Externí odkaz:
https://doaj.org/article/4a55370cc5e9433fba966df0b7a4bf30
Autor:
Haiyuan Zhang, Yunlong Lei, Ping Yuan, Lingjun Li, Chao Luo, Rui Gao, Jun Tian, Zuohua Feng, Edouard C Nice, Jun Sun
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96418 (2014)
Gambogic acid (GA), the main active component of gamboge resin, has potent antitumor activity both in vivo and in vitro. However, the underlying molecular mechanisms remain unclear. In this study, we found that GA could initiate autophagy in colorect
Externí odkaz:
https://doaj.org/article/ba48d38e5be04cd38e12896d29bb76d9
Autor:
Jiufei Duan, Zhao Huang, Siyuan Qin, Bowen Li, Zhe Zhang, Rui Liu, Kui Wang, Edouard C. Nice, Jingwen Jiang, Canhua Huang
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) play a crucial role in triggering tumour‐aggressive behaviours. However, the energetic process by which tumour cells produce EVs remains poorly understood. Here, we demonstrate the involvement of β‐hexosamin
Externí odkaz:
https://doaj.org/article/b843fd2824794d81ac98596eea7cbea2
Autor:
David S Williams, Matthew J Bird, Robert N Jorissen, Yen Lin Yu, Francesca Walker, Hui Hua Zhang, Edouard C Nice, Antony W Burgess
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e16012 (2010)
BackgroundFrameshift mutations in microsatellite instability high (MSI-High) colorectal cancers are a potential source of targetable neo-antigens. Many nonsense transcripts are subject to rapid degradation due to nonsense-mediated decay (NMD), but no
Externí odkaz:
https://doaj.org/article/579d75d8604d495ba6ee8a4b34dc0642