Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edorta Martínez de Marigorta"'
Autor:
Edorta Martínez de Marigorta, Jesús M. de Los Santos, Ana M. Ochoa de Retana, Javier Vicario, Francisco Palacios
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1065-1085 (2019)
Benzo-fused γ-lactam rings such as isoindolin-2-ones and 2-oxindoles are part of the structure of many pharmaceutically active molecules. They can be often synthesized by means of multicomponent approaches and recent contributions in this field are
Externí odkaz:
https://doaj.org/article/5bc34c6c1f5c4dea95c3cede933fd43b
Autor:
Adrián López-Francés, Xabier del Corte, Zuriñe Serna-Burgos, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario
Publikováno v:
Molecules, Vol 27, Iss 11, p 3624 (2022)
A study on the reactivity of 3-amino α,β-unsaturated γ-lactam derivatives obtained from a multicomponent reaction is presented. Key features of the substrates are the presence of an endocyclic α,β-unsaturated amide moiety and an enamine function
Externí odkaz:
https://doaj.org/article/1307114b550f452c99e2a129cd53ae0e
Autor:
Xabier del Corte, Adrián López-Francés, Ilia Villate-Beitia, Myriam Sainz-Ramos, Edorta Martínez de Marigorta, Francisco Palacios, Concepción Alonso, Jesús M. de los Santos, José Luis Pedraz, Javier Vicario
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 511 (2022)
We report efficient synthetic methodologies for the preparation of 3-amino and 3-hydroxy 3-pyrrolin-2-ones (unsaturated γ-lactams) through a multicomponent reaction of amines, aldehydes and acetylene or pyruvate derivatives. The densely substituted
Externí odkaz:
https://doaj.org/article/4dab7780eb6b4c9e8a9854cea1fa5ffc
Autor:
Xabier del Corte, Adrián López-Francés, Aitor Maestro, Ilia Villate-Beitia, Myriam Sainz-Ramos, Edorta Martínez de Marigorta, José Luis Pedraz, Francisco Palacios, Javier Vicario
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 782 (2021)
An efficient synthetic methodology for the preparation of 3-amino 1,5-dihydro-2H-pyrrol-2-ones through a multicomponent reaction of amines, aldehydes, and pyruvate derivatives is reported. In addition, the densely substituted lactam substrates show i
Externí odkaz:
https://doaj.org/article/e375b54fa6eb47ecb582cc7e02854683
Autor:
Aitor Maestro, Xabier del Corte, Adrián López-Francés, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario
Publikováno v:
Molecules, Vol 26, Iss 11, p 3202 (2021)
Due to their structural similarity with natural α-amino acids, α-aminophosphonic acid derivatives are known biologically active molecules. In view of the relevance of tetrasubstituted carbons in nature and medicine and the strong dependence of the
Externí odkaz:
https://doaj.org/article/8e64a6abbfbb4ff6afa51c93f1e8e9d5
Autor:
Adrián López-Francés, Xabier del Corte, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario
Publikováno v:
Molecules, Vol 26, Iss 6, p 1654 (2021)
An Ugi three-component reaction using preformed α-phosphorated N-tosyl ketimines with different isocyanides in the presence of a carboxylic acid affords tetrasubstituted α-aminophosphonates. Due to the high steric hindrance, the expected acylated a
Externí odkaz:
https://doaj.org/article/bd83ba60f2774eb98ef377f29aa8c933
Autor:
Xabier del Corte, Adrián López-Francés, Edorta Martinez de Marigorta, Francisco Palacios, Javier Vicario
Publikováno v:
Molbank, Vol 2021, Iss 2, p M1218 (2021)
The title compound is a hydantoin derivative that has been synthesized through a three-component reaction of ethyl pyruvate, p-anisidine and phenyl isocyanate. This paper provides a comprehensive spectral dataset for the title compound, including 1H
Externí odkaz:
https://doaj.org/article/f96acf3f17124182bd68a63455022f22
Publikováno v:
Molecules, Vol 24, Iss 16, p 2951 (2019)
Brønsted acids catalyze a multicomponent reaction of benzaldehyde with amines and diethyl acetylenedicarboxylate to afford highly functionalized γ-lactam derivatives. The reaction consists of a Mannich reaction of an enamine to an imine, both gener
Externí odkaz:
https://doaj.org/article/deca4b89bd2647d387d3e1bd26f8457e