Zobrazeno 1 - 10
of 881
pro vyhledávání: '"Edoardo SPINA"'
Autor:
Catia Scassellati, Nadia Cattane, Francesco Benedetti, Tiziana Borsello, Giuseppe Cicala, Massimo Gennarelli, Patrizia Genini, Alessandro Gialluisi, Arianna Giani, Licia Iacoviello, Alessandra Minelli, Edoardo Spina, Benedetta Vai, Erika Vitali, Annamaria Cattaneo
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100886- (2024)
About one third of patients suffering from Major Depressive Disorder (MDD) do not respond to any antidepressant medications and 75% experience relapses and general health deterioration. Importantly, inflammation can contribute to such negative outcom
Externí odkaz:
https://doaj.org/article/e5fab3571a3742abacd8434797d0381e
Autor:
Giuseppe Cicala, Michelangelo Rottura, Viviana Maria Gianguzzo, Federica Cristiano, Selene Francesca Anna Drago, Giovanni Pallio, Natasha Irrera, Egidio Imbalzano, Edoardo Spina, Vincenzo Arcoraci
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1365 (2024)
Introduction: The discovery of serine protease proprotein convertase subtilisin-kexin type 9 (PCSK9) has revolutionized pharmacological lipid-lowering treatments. The first PCSK9 antagonists (PCSK9-A), evolocumab and alirocumab, were approved in 2015
Externí odkaz:
https://doaj.org/article/163ee951ebe44597bb3b14b6b7c86479
Autor:
Giuseppe Cicala, Giulia Russo, Vincenza Santoro, Tindara Franchina, Nicola Silvestris, Mariacarmela Santarpia, Edoardo Spina, Maria Antonietta Barbieri
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1266 (2024)
Background/Objectives: Monoclonal antibodies (mAbs) have revolutionized multiple myeloma (MM) treatment. However, post-marketing data on their neuropsychiatric safety are limited. This study aimed to evaluate neuropsychiatric adverse events (AEs) rel
Externí odkaz:
https://doaj.org/article/a2102702411a440f99989448bbce7189
Autor:
Maria Antonietta Barbieri, Giulia Russo, Emanuela Elisa Sorbara, Giuseppe Cicala, Tindara Franchina, Mariacarmela Santarpia, Desirèe Speranza, Edoardo Spina, Nicola Silvestris
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionNew oral tyrosine kinase inhibitors (TKIs) are approved for metastatic colorectal cancer (mCRC). The aim of this study was to assess the neuropsychiatric adverse drug reactions (ADRs) of these drugs reported in the FDA Adverse Event Repor
Externí odkaz:
https://doaj.org/article/87a2edba3ea14c94985a7c3c20f8fd29
Autor:
Antonio Vita, Andrea Fagiolini, Giuseppe Maina, Claudio Mencacci, Edoardo Spina, Silvana Galderisi
Publikováno v:
Annals of General Psychiatry, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Definition of an appropriate and personalized treatment plan focused on long-term outcomes is crucial in the management of schizophrenia. Following review of the literature, a panel of six leading psychiatrists discussed the importance of cl
Externí odkaz:
https://doaj.org/article/caf4071126744394b03c314c1e2f1a66
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/66b1eb78503a452a8f1e0bd7fb43490e
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 342 (2024)
Daridorexant (dari), as the first dual orexin receptor antagonist (DORA) marketed in Europe, offers a novel therapeutic approach to insomnia. However, data regarding its real-world safety are scarce. Thus, this study was aimed at assessing its safety
Externí odkaz:
https://doaj.org/article/7d4c954fcfbd4dc595ad457da8a8e611
Autor:
Giuseppe Cicala, Renato de Filippis, Maria Antonietta Barbieri, Paola Maria Cutroneo, Pasquale De Fazio, Georgios Schoretsanitis, Edoardo Spina
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionLong-acting injectable antipsychotics (LAIs) have proven to be effective in the maintenance treatment of patients suffering from schizophrenia, and their safety and tolerability profiles represent a key factor in their long-term use and c
Externí odkaz:
https://doaj.org/article/a67b21a203e14d55a77a11b2081d7d8d
Autor:
Alessandra Minelli, Stefano Barlati, Erika Vitali, Stefano Bignotti, Vincenzo Dattilo, Giovanni Battista Tura, Elisabetta Maffioletti, Edoardo Giacopuzzi, Vincenza Santoro, Giulia Perusi, Chiara Cobelli, Chiara Magri, Silvia Bonizzato, Luisella Bocchio-Chiavetto, Edoardo Spina, Antonio Vita, Massimo Gennarelli
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Major depressive disorder (MDD) is a common, chronic, debilitating mood disorder that causes serious functional impairment and significantly decreased quality of life. Pharmacotherapy represents the first-line treatment option; ho
Externí odkaz:
https://doaj.org/article/6ad0c3e7914740e486e0b6fa4b29ab0b
Autor:
Maria Antonietta Barbieri, Emanuela Elisa Sorbara, Giuseppe Cicala, Vincenza Santoro, Paola Maria Cutroneo, Tindara Franchina, Mariacarmela Santarpia, Nicola Silvestris, Edoardo Spina
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionNon-small cell lung cancer (NSCLC) is often caused by molecular alterations that can be detected by predictive biomarkers including mutations or amplifications of several genes. Several tyrosine kinase inhibitors (TKIs) have been approved
Externí odkaz:
https://doaj.org/article/536460645505447e93c7d0aceec0ee1a