Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Edo Elstak"'
High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis
Autor:
Bart Kramer, Claudio Corallo, Angelique van den Heuvel, Justin Crawford, Thomas Olivier, Edo Elstak, Nicola Giordano, Paul Vulto, Henriette L. Lanz, Richard A. J. Janssen, Michela A. Tessari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In early systemic sclerosis (Scleroderma, SSc), the vasculature is impaired. Although the exact etiology of endothelial cell damage in SSc remains unclear, it is hypothesized that endothelial to mesenchymal transition (EndoMT) plays a key ro
Externí odkaz:
https://doaj.org/article/b86b2506caae477e830bdb7df0ff544d
Autor:
Olaf Voets, Frans Tielen, Edo Elstak, Julian Benschop, Max Grimbergen, Jan Stallen, Richard Janssen, Andre van Marle, Christian Essrich
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182974 (2017)
Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (KD) of such targets in these assays allows the investigation of their role in models of disease process
Externí odkaz:
https://doaj.org/article/6f9bc66354654582bb8bb43548d5c92a
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15318 (2010)
Human cytomegalovirus (HCMV) completes its final envelopment on intracellular membranes before it is released from the cell. The mechanisms underlying these processes are not understood. Here we studied the role of Rab27a, a regulator of lysosome-rel
Externí odkaz:
https://doaj.org/article/4c1b39c5918342f28f194c8d0173d4a7
Publikováno v:
Methods in enzymology. 438
Secretory lysosomes constitute a heterogeneous organelle of hematopoietic cells that combines the properties of regular lysosomes with those of secretory granules. Although secretory lysosomes serve essential functions, such as in the immune system a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1125a87726cf41a6a8c0794c46336faf
https://pubmed.ncbi.nlm.nih.gov/18413249
https://pubmed.ncbi.nlm.nih.gov/18413249