Výsledky vyhledávání - "Edneia A.S. Ramos"

Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms

Autor: Edneia A.S. Ramos, Maria Élida Alves Stefanello, Alexandra Acco, Débora Rasec Radulski, Cristhian Santos Oliveira, Maria Carolina Stipp, Giseli Klassen, José Ederaldo Queiroz Telles, Marihá Mariott, Claudia Rita Corso, Luisa Mota da Silva, Arthur J. Verhoeven, Ronald P.J. Oude Elferink

Publikováno v: Scientific reports, 10(1):16477. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Natural products have been recognized as important bioactive compounds on the basis of their wide biological properties. Here we investigated the antitumor effect and molecular mechanisms of the diterpene Fruticuline A (fruti) from Salvia lachnostach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b40dcdf827b5078786126377c56d5e
https://pure.amc.nl/en/publications/fruticuline-a-a-chemicallydefined-diterpene-exerts-antineoplastic-effects-in-vitro-and-in-vivo-by-multiple-mechanisms(986262d7-bc05-4bdc-8af0-f0fcd2f55147).html

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DNA Methylation Status of the Estrogen Receptor α Gene in Canine Mammary Tumors

Autor: Thierry Grima de Cristo, Mariana Busato Toledo, Giseli Klassen, Renato Silva de Sousa, Andressa Chequin, Yara de Oliveira Brandão, Edneia A.S. Ramos

Publikováno v: Veterinary Pathology. 55:510-516

Estrogen receptor α (ERα) has an important role in mammary carcinogenesis, prognosis, and treatment. In human and canine mammary cancer, the most aggressive tumors show loss of ERα expression, which in human breast cancer has been attributed to me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d938eda203429f7bbdb96607b729b2e
https://doi.org/10.1177/0300985818763711

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Epigenetic regulation of SLC11a1 gene in horses infected with cyathostomins

Autor: Angie D.B. Moncada, Luciana Laitano Dias de Castro, Giseli Klassen, Guilherme Augusto Minozzo, Marcelo Beltrão Molento, Verônica S. Pires, Fernando A. de O. Ganzella, Edneia A.S. Ramos

Publikováno v: Gene Reports. 25:101410

Cyathostomins are the most prevalent nematode parasites of horses worldwide and the SLC11a1 gene has been found to modulate the host immune response against parasite infections. The objective of this work was to determine the DNA methylation profile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::310579530a44dd62c53171ea5957d072
https://doi.org/10.1016/j.genrep.2021.101410

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Polysaccharides from green sweet pepper increase the antineoplastic effect of methotrexate on mammary tumor cells

Autor: Maria Carolina Stipp, Alexandra Acco, Letícia Milani, Marihá Mariott, Giseli Klassen, Natalia Mulinari Turin-Oliveira, Liziane Cristine Malaquias da Silva, Georgia Erdmann do Nascimento, Claudia Martins Galindo, Edneia A.S. Ramos, Pedro Felipe Pereira Chaves, Eliana Rezende Adami, Claudia Rita Corso, Luisa Mota da Silva, Andressa Chequin, Lucimara M.C. Cordeiro

Publikováno v: International journal of biological macromolecules. 158

This study investigated the antineoplastic effects and toxicity of long-term treatment with polysaccharides from sweet green pepper (Capsicum annuum [CAP]), and concomitant treatment with CAP + methotrexate (MTX) on mammary tumor cells in vivo and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0a1cfe8d921700ea0ca796b8fe109b
https://pubmed.ncbi.nlm.nih.gov/32387356

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Salvia lachnostachys Benth has antitumor and chemopreventive effects against solid Ehrlich carcinoma

Autor: Cristhian Santos Oliveira, Maria Élida Alves Stefanello, Maria Carolina Stipp, José Ederaldo Queiroz-Telles, Sérgio Faloni de Andrade, Alexandra Acco, Eliana Rezende Adami, Olair Carlos Beltrame, Marihá Mariott, Giseli Klassen, Claudia Rita Corso, Luisa Mota da Silva, Edneia A.S. Ramos

Publikováno v: Molecular biology reports. 46(5)

Salvia lachnostachys is an herbaceous plant with anti-inflammatory, analgesic and cytotoxic properties. This study investigated the antitumor effect of an ethanolic extract of Salvia lachnostachys leaves (EES) in a solid Ehrlich carcinoma model. Ehrl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67761a53a6b58008b8b4c51f1b6766c9
https://pubmed.ncbi.nlm.nih.gov/31270760

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Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the Hospital de Clínicas da Universidade Federal do Paraná during the period 2008-2013

Autor: Heloisa Z. Rocha, Edneia A.S. Ramos, Graciele C. M. Manica, Giseli Klassen, Lucia de Noronha

Publikováno v: Jornal Brasileiro de Patologia e Medicina Laboratorial v.55 n.1 2019
Jornal Brasileiro de Patologia e Medicina Laboratorial
Sociedade Brasileira de Patologia (SBP)
instacron:SBP
Jornal Brasileiro de Patologia e Medicina Laboratorial, Volume: 55, Issue: 1, Pages: 69-86, Published: 09 MAY 2019

Introduction: Breast cancer is the second leading cause of cancer death among women worldwide, and epidemiological studies may help understanding its mechanisms. Objective: To carry out a survey of the number of breast cancer cases diagnosed in a per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c9f03e13e1c731966abf9650337d6d
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100069

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MMP9 gene expression regulation by intragenic epigenetic modifications in breast cancer

Autor: Graciele C. M. Manica, Mariana Busato Toledo, Giseli Klassen, Emanuel Maltempi de Souza, Valter Antonio de Baura, Andressa Chequin, Fábio O. Pedrosa, Liliane M. B. Klassen, Isis V. Biembengut, Edneia A.S. Ramos, Fabricio F. Costa

Publikováno v: Gene. 642

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among women worldwide. Metastasis remains a major challenge for the clinical management and prognosis of patients with cancer. The metalloprotease MMP-9 plays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c25176d5a8bf12232e4bcf77172911f
https://pubmed.ncbi.nlm.nih.gov/29162512

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Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population

Autor: Dayane Alberton, Bruna Rodrigues Martins, Mauren Isfer Anghebem-Oliveira, Geraldo Picheth, Fabiane Gomes de Moraes Rego, Edneia A.S. Ramos

Publikováno v: Archives of Endocrinology and Metabolism v.61 n.3 2017
Arquivos de Endocrinologia e Metabolismo
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Archives of Endocrinology and Metabolism, Vol 61, Iss 3, Pp 238-248 (2017)
Archives of Endocrinology and Metabolism, Volume: 61, Issue: 3, Pages: 238-248, Published: 27 MAR 2017

Objective Gestational diabetes mellitus (GDM) is a metabolic disorder that shares pathophysiologic features with type 2 diabetes mellitus. The aim of this study was to investigate the association of the polymorphisms fat mass and obesity-associated (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e4fe9a45d4b5b56b91707e26e045cd
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972017000300238

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