Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Edmund V Capparelli"'
Autor:
Xiaomei I. Liu, André Dallmann, Kristina Brooks, Brookie M. Best, Diana F. Clarke, Mark Mirochnick, John N. van denAnker, Edmund V. Capparelli, Jeremiah D. Momper
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 2, Pp 148-153 (2023)
Abstract Pregnant individuals are at high risk for severe illness from COVID‐19, and there is an urgent need to identify safe and effective therapeutics for this population. Remdesivir (RDV) is a SARS‐CoV‐2 nucleotide analog RNA polymerase inhi
Externí odkaz:
https://doaj.org/article/d52f04c0444447639aa5582982613a39
Autor:
María L. Cafferata, María A. Toscani, Fernando Althabe, Jose M. Belizán, Eduardo Bergel, Mabel Berrueta, Edmund V. Capparelli, Álvaro Ciganda, Emmaria Danesi, Eric Dumonteil, Luz Gibbons, Pablo E. Gulayin, Claudia Herrera, Jeremiah D. Momper, Steven Rossi, Jeffrey G. Shaffer, Alejandro G. Schijman, Sergio Sosa-Estani, Candela B. Stella, Karen Klein, Pierre Buekens
Publikováno v:
Reproductive Health, Vol 17, Iss 1, Pp 1-23 (2020)
Resumen (Spanish) Antecedentes Estudios observacionales retrospectivos sugieren que la transmisión del Trypanosoma cruzi no ocurre en mujeres tratadas cuando quedan embarazadas más adelante. La carga parasitaria en la sangre es un factor de riesgo
Externí odkaz:
https://doaj.org/article/683cfa5293dc4f14bd873f0d1058feaf
Autor:
Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, Macpherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, Karl B. Seydel
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression. We undertook studies of enteral levetiracetam (eLVT) to evaluate pharmacokinetics (PK), safety and effi
Externí odkaz:
https://doaj.org/article/6600377b119e4395bbbb1702f9b8751d
Autor:
Sherry Zhao, Mary Gockenbach, Manuela Grimstein, Hari Cheryl Sachs, Mark Mirochnick, Kimberly Struble, Yodit Belew, Jian Wang, Edmund V. Capparelli, Brookie M. Best, Tamara Johnson, Jeremiah D. Momper, Anil R. Maharaj
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Alterations in plasma protein concentrations in pregnant and postpartum individuals can influence antiretroviral (ARV) pharmacokinetics. Physiologically-based pharmacokinetic (PBPK) models can serve to inform drug dosing decisions in unde
Externí odkaz:
https://doaj.org/article/255de7edd5bf4599bab6e29d0798c310
Autor:
Kensuke Shoji, Jumpei Saito, Hidenori Nakagawa, Takanori Funaki, Akinari Fukuda, Seisuke Sakamoto, Mureo Kasahara, Jeremiah D. Momper, Edmund V. Capparelli, Isao Miyairi
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Methicillin-resistant Staphylococcus aureus infections are a significant cause of morbidity and mortality in pediatric liver transplant (LT) recipients. Physiological changes following LT may affect vancomycin pharmacokinetics; however, appr
Externí odkaz:
https://doaj.org/article/87a74edb86db42bca17204276cec3163
Autor:
Kirsten E Lyke, Andrea A Berry, Kaitlin Mason, Azza H Idris, Mark O'Callahan, Myra Happe, Larisa Strom, Nina M Berkowitz, Mercy Guech, Zonghui Hu, Mike Castro, Manjula Basappa, Lu Wang, Kwang Low, LaSonji A Holman, Floreliz Mendoza, Ingelise J Gordon, Sarah H Plummer, Olga Trofymenko, Kathleen S Strauss, Sudhaunshu Joshi, Biraj Shrestha, Matthew Adams, Andrezza Campos Chagas, Jittawadee R Murphy, Judy Stein, Somia Hickman, Andrew McDougal, Bob Lin, Sandeep R Narpala, Sandra Vazquez, Leonid Serebryannyy, Adrian McDermott, Martin R Gaudinski, Edmund V Capparelli, Emily E Coates, Richard L Wu, Julie E Ledgerwood, Lesia K Dropulic, Robert A Seder, Cheryl Young, Colleen Boyce, Jennifer Winkler, Susan Holian, Nancy Greenberg, Shirley George, Alyson Kwon, Brenda Dorsey, Ana Raquel Da Costa, William Witt, Daryl Grays, Arren Gapasin, Paula Bernal, Jeffrey Floyd, Eric Goldstein, Leslie Howe, Myounghee Lee, Jennifer Marron, Kelly Brooks, Lisa Turek, Patricia Farley, Shantel Frels, Delores Booth, Jason Gall, Kevin Carlton, Gabriela Albright, Nadia Amharref, Kandace Atallah, Sashikanth Banappagari, Niutish Bastani, Daniel Blackstock, Bobby Boonyaratanakornkit, Elizabeth Carey, Adam Charlton, Rajoshi Chaudhuri, Alegria M. Caringal, Mingzhong Chen, Peifeng Chen, Wei Cheng, Daniel Gowetski, Krishana Gulla, Erica Hastings, Joe Horwitz, Vera Ivleva, Dan Kordella, Lisa A. Kueltzo, Sara Lagler, Matt Le, James Lee, Paula Lei, Yile Li, Attila Nagy, Aakash Patel, Peyi Runsewe, Will Shadrick, Shamitha Shetty, Hairong Wang, Calvin Webber, Farah Vejzagic, Yoo-Jung Yang
Publikováno v:
The Lancet Infectious Diseases. 23:578-588
Autor:
Gbolahan Ajibola, Kenneth Maswabi, Michael D. Hughes, Kara Bennett, Molly Pretorius-Holme, Edmund V. Capparelli, Patrick Jean-Philippe, Sikhulile Moyo, Terence Mohammed, Oganne Batlang, Maureen Sakoi, Lucia Ricci, Shahin Lockman, Joseph Makhema, Daniel R. Kuritzkes, Mathias Lichterfeld, Roger L. Shapiro
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 92:393-398
Autor:
Sharana Mahomed, Nigel Garrett, Edmund V Capparelli, Farzana Osman, Nonhlanhla N Mkhize, Ishana Harkoo, Tanuja N Gengiah, Leila E Mansoor, Cheryl Baxter, Derseree Archary, Nonhlanhla Yende-Zuma, Natasha Samsunder, Kevin Carlton, Sandeep Narpala, Adrian B McDermott, Nicole A Doria-Rose, Penny L Moore, Lynn Morris, Quarraisha Abdool Karim, John R Mascola, Salim S Abdool Karim
Publikováno v:
The Lancet HIV. 10:e230-e243
Autor:
Xiaomei I. Liu, André Dallmann, Kristina Brooks, Brookie M. Best, Diana F. Clarke, Mark Mirochnick, John N. van den Anker, Edmund V. Capparelli, Jeremiah D. Momper
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:148-153
Autor:
Steven Dunne, Andrew R. Willmer, Rosemary Swanson, Deepak Almeida, Nicole C. Ammerman, Kathleen A. Stringer, Edmund V. Capparelli, Gus R. Rosania
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 15 (2021)
Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19. CFZ exhibits complex, context-dependent ph
Externí odkaz:
https://doaj.org/article/04a8bb12f7d24456b7b5804dc83f18c1