Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Edmund Tischer"'
Autor:
Edmund Tischer, Barbara Cordell
Publikováno v:
Journal of Biological Chemistry. 271:21914-21919
The formation of β-amyloid by processing of its precursor protein is a characteristic of Alzheimer's disease. Two proteolytic cleavages produce the amino and carboxyl termini of β-amyloid, with the latter cleavage site located within the transmembr
Autor:
Edmund Tischer, Axel Ullrich, Howard M. Goodman, Chirgwin John Mitchell, John Shine, William J. Rutter, Raymond Pictet
Publikováno v:
Science. 196:1313-1319
Recombinant bacterial plasmids have been constructed that contain complementary DNA prepared from rat islets of Langerhans messenger RNA. Three plasmids contain cloned sequences representing the complete coding region of rat proinsulin I, part of the
Autor:
Tracey Crisp, Kenneth K. Lau, John C. Fiddes, Maria Elena Silva, James W. Schilling, Denis Gospodarowicz, Richard Mitchell, Judith A. Abraham, Edmund Tischer
Publikováno v:
Biochemical and Biophysical Research Communications. 165:1198-1206
Using applications of the polymerase chain reaction (PCR) technique, cDNA clones have been isolated encoding bovine vascular endothelial growth factor (VEGF), a mitogen with specificity for vascular endothelial cells. Analysis of the clones indicates
Publikováno v:
Molecular and General Genetics MGG. 203:221-229
One of the members of the small gene family encoding glutamine synthetase in alfalfa (Medicago sativa L.) has been cloned and its nucleotide sequence determined. Approximately full length cDNAs corresponding to the gene have also been cloned and thei
Autor:
Edmund Tischer, Axel Ullrich, William J. Rutter, Barbara Cordell, Howard M. Goodman, Frances M. Denoto, Raymond Pictet, Graeme I. Bell
Publikováno v:
Cell. 18:533-543
The two nonallelic genes, insulin I and II of the rat, are separated by at least 7 kb of DNA. There is no obvious similarity in the sequence organization surrounding each gene, although the coding regions of the genes themselves share extensive homol
Publikováno v:
Science. 232:1242-1244
A glutamine synthetase gene from alfalfa (Medicago sativa) has been expressed in Escherichia coli after fusion of bacterial transcription and translation signals to a complete alfalfa glutamine synthetase coding sequence. Synthesis of the alfalfa glu
Autor:
Edmund Tischer, John C. Fiddes, Annette Tumolo, Judy Miller, Denis Gospodarowicz, Judith A. Abraham, David Graves, Ayalew Mergia, Gary D. Shipley
Publikováno v:
Biochemical and biophysical research communications. 164(3)
Genomic clones derived from the gene for human acidic fibroblast growth factor (aFGF) have been isolated. Nucleotide sequence analysis of these clones revealed that the coding region of the human aFGF gene is interrupted by two introns, located at pr
Autor:
Edmund Tischer, Raymond Pictet, Howard M. Goodman, Barbara Cordell, Graeme I. Bell, William J. Rutter
Publikováno v:
Nature. 284(5751)
The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5'-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region. A comparison of the human with the rat insulin genes
Autor:
Howard M. Goodman, A P Czernilofsky, J M Bishop, W. J. DeLorbe, Ronald Swanstrom, Edmund Tischer, Harold E. Varmus
The genomes of numerous avian retroviruses contain at their 3′ termini a conserved domain denoted "c". The precise boundaries and function of "c" have been enigmas. In an effort to resolve these issues, we determined the sequerce of over 900 nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b68630e5fc0ddb8f9770c3a8443a6b6
https://europepmc.org/articles/PMC324138/
https://europepmc.org/articles/PMC324138/