Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Edmund P. Harrigan"'
Autor:
J.J. Miceli, Karen R. Reeves, Watsky Eric Jacob, Neal R. Cutler, T. John Sramek, Michelle Middle, R.J. Anziano, Edmund P. Harrigan, Thomas Shiovitz
Publikováno v:
Journal of Clinical Psychopharmacology. 24:62-69
Many drugs have been associated with QTc prolongation and, in some cases, this is augmented by concomitant administration with metabolic inhibitors. The effects of 6 antipsychotics on the QTc interval at and around the time of estimated peak plasma/s
Publikováno v:
Progress in Cardiovascular Diseases. 43:1-45
The effects of disease states and therapeutic drugs on the QT interval have been extensively studied in an attempt to understand the relationship between QT and the risk of torsade de pointes and sudden cardiac death. Differences in heart rate correc
Publikováno v:
Psychopharmacology. 155:128-134
Rationale: Intramuscular (IM) conventional antipsychotics and/or benzodiazepines are effective in the short-term treatment of acutely agitated psychotic patients but may be associated with adverse effects. A short-acting IM formulation of the novel a
Publikováno v:
Journal of Clinical Psychopharmacology. 21:27-35
This study assessed the efficacy of ziprasidone for the treatment of schizoaffective disorder. Data were taken from subsets of patients with schizoaffective disorder, derived from two separate double-blind, placebo-controlled, parallel-group, multice
Autor:
David G. Daniel, Steven G. Potkin, Mani Lakshminarayanan, Karen R. Reeves, Edmund P. Harrigan, Dan L. Zimbroff
Publikováno v:
Neuropsychopharmacology. 20:491-505
In this double-blind study, patients with an acute exacerbation of schizophrenia or schizoaffective disorder were randomized to receive either ziprasidone 80 mg/day (n = 106) or 160 mg/day (n = 104) or placebo (n = 92), for 6 weeks. Both doses of zip
Autor:
Feighner Jp, Marilyn R. Morrissey, Alan Buffenstein, Edmund P. Harrigan, James Ferguson, William Jaffe, Paul E. Keck
Publikováno v:
Psychopharmacology. 140:173-184
A double-blind, placebo-controlled, multicenter study, was performed to evaluate the efficacy and safety of ziprasidone in 139 patients with an acute exacerbation of schizophrenia or schizoaffective disorder. Patients were randomized to receive zipra
Publikováno v:
International clinical psychopharmacology. 19(1)
The intramuscular (i.m.) formulation of ziprasidone offers promise as an alternative to conventional i.m. agents for the short-term management of agitated patients with psychosis. This 7-day, randomized, open-label study evaluated the tolerability of
Publikováno v:
The American journal of cardiology. 89(11)
Autor:
Kevin R. Fontaine, Edmund P. Harrigan, Charles L. Shear, David B. Allison, Mani Lakshminarayanan, Daniel E. Casey, Moonseong Heo
Publikováno v:
Psychiatry research. 101(3)
Many anti-psychotic medications produce marked weight gain. In this study, we estimate the expected impact of degrees of antipsychotic-induced weight gain on selected mortality rate and incidence rates of impaired glucose tolerance (IGT) and hyperten
Publikováno v:
The Journal of clinical psychiatry. 62(1)
Background: There is a clear need for effective, well-tolerated intramuscular (i.m.) agents for the acute control of agitated psychotic patients. Currently used agents, including conventional antipsychotics and/or benzodiazepines, may be associated w