Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Edmund H. Sonnenblick"'
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 18(3)
The effects of angiotensin II on circulatory dynamics and coronary blood flow were studied in the cat. With equal single doses of angiotensin II and norepinephrine a greater blood pressure response occurred with angiotensin. With continuous administr
Publikováno v:
Cardiovascular drugs and therapy. 2(Suppl 1)
Congestive heart failure (CHF) evolves either from an excessive workload or in response to loss of myocardium, both of which cause cardiac hypertrophy, increased cardiac pressure, and loss of functional reserve. Nearly 60% of patients in heart failur
Autor:
Ricardo Bello, Robert J. Ostfeld, Edmund H. Sonnenblick, M.P.H. Hillel W. Cohen Ph.D., Reza Nazari, Liran Blum, Daniel M. Spevack, Sanjay Doddamani, Divya Malhotra
Publikováno v:
Echocardiography. 25:366-373
BACKGROUND Classification of diastolic heart function is best defined by the degree of leftward and upward shift of the diastolic pressure-volume relationship (DPVR). Direct measurement of DPVR, however, requires invasive techniques. Increased left a
Publikováno v:
Journal of Molecular and Cellular Cardiology. 40:425-437
In the last decade, apoptosis has gained recognition as an important event determining the structure and function of the myocardium. The purpose of this review is to provide insights into the mechanisms controlling programmed cell death of myocytes.
Autor:
Toru Hosoda, Roberto Bolli, Annarosa Leri, Marcello Rota, Jan Kajstura, Edmund H. Sonnenblick, Piero Anversa, Konrad Urbanek
Publikováno v:
Basic Research in Cardiology. 100:482-493
This review questions the old paradigm that describes the heart as a post-mitotic organ and introduces the notion of the heart as a self-renewing organ regulated by a compartment of multipotent cardiac stem cells (CSCs) capable of regenerating myocyt
Autor:
Peter J. Schwartz, A. John Camm, Jose Brum, Hussein R. Al-Khalidi, Edmund H. Sonnenblick, Roger Karam, Michael J. Holroyde, Craig M. Pratt, Maria J. Spyt
Publikováno v:
Circulation. 109:990-996
Background— Depressed left ventricular function (LVF) and low heart rate variability (HRV) identify patients at risk of increased mortality after myocardial infarction (MI). Azimilide, a novel class III antiarrhythmic drug, was investigated for its
Autor:
Edmund H. Sonnenblick
Publikováno v:
The American Journal of Cardiology. 88:19-27
Congestive heart failure (CHF) is the most common and lethal consequence of atherosclerotic cardiovascular disease, with a prevalence estimated between 1% and 10%, and very high associated mortality. Preventing the continued progression of establishe
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 1 (2000)
JRAAS 2000;1:147-50 Introduction Decreasing activation of the renin-angiotensinaldosterone system (RAAS) is an essential target of the pharmacological treatment of patients with congestive heart failure (CHF). Several large, randomised, placebo-contr
Autor:
Baosheng Li, Jan Kajstura, Fabio Fiordaliso, Roberto Latini, Annarosa Leri, Edmund H Sonnenblick, Piero Anversa
Publikováno v:
Laboratory Investigation. 80:513-527
To determine whether myocyte death and angiotensin II (AT II) formation are implicated in the development of diabetic cardiomyopathy, rats were injected with streptozotocin, and apoptosis and necrosis were measured at 3, 10, and 28 days. Expression o
Autor:
O. H. Frazier, Edmund H. Sonnenblick, Michael R. Bristow, Leslie A. Leinwand, A. J. Moss, Jay N. Cohn, Leslie Reinlib, B. H. Lorell, Richard A. Walsh, Stephen C. Mockrin, Wilson S. Colucci, Kenneth R. Chien
Publikováno v:
Circulation. 95:766-770
The SEP identified priorities to support in future basic and clinical research and pointed out directions likely to result in advances against heart failure. The list is not intended to be all-encompassing and does not address, for example, exciting