Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edmund Gosselin"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Adjuvants have been used in vaccines for over a century, however, the search for safe and effective vaccine adjuvants continues. In recent decades toll-like-receptor (TLR) agonists have been investigated as potential vaccine adjuvants. In this regard
Externí odkaz:
https://doaj.org/article/05766233eb614cf4ad5db146b279ee37
Five-day-old mouse pups were fed either Prevnar 13 alone or peripheral blood mononuclear cells (PBMCs) isolated from adult donors and pulsed _ex vivo_ with Prevnar-13. Mice vaccinated with Prevnar-13 or with vaccine-pulsed PBMCs displayed a positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca892539267511c8b903e4d3d81d94c4
https://doi.org/10.32388/xtgwdk.2
https://doi.org/10.32388/xtgwdk.2
Publikováno v:
Immunological Investigations. 34:53-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73be38386531855a6fd15833165f69ea
https://doi.org/10.1081/imm-200047385
https://doi.org/10.1081/imm-200047385
Publikováno v:
The Journal of Immunology. 192:141.9-141.9
We have previously demonstrated that intranasal (i.n.) immunization with inactivated Francisella tularensis (Ft) live vaccine strain (LVS) targeted to Fcγ receptors (FcγR) can induce partial protection against a lethal mucosal challenge with Ft Sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dec650d7f61865f38ca0a540c7ba6d7
https://doi.org/10.4049/jimmunol.192.supp.141.9
https://doi.org/10.4049/jimmunol.192.supp.141.9
Autor:
Edmund Gosselin, Constantine Bitsaktsis, Bibiana Iglesias, Giang Pham, James Drake, Clifford Snapper, Brian Franz
Publikováno v:
The Journal of Immunology. 190:54.14-54.14
We previously demonstrated that immunization with inactivated Francisella tularensis, a Category A intracellular mucosal pathogen, combined with anti-F. tularensis mAb, enhances protection against F. tularensis challenge. We thus sought to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da7b99192b3e994b22ea1b39d5ba607c
https://doi.org/10.4049/jimmunol.190.supp.54.14
https://doi.org/10.4049/jimmunol.190.supp.54.14
Publikováno v:
The Journal of Immunology. 190:54.13-54.13
Numerous studies have demonstrated that targeting antigens to FcγR can increase their immunogenicity and generate protective immune responses in various infection models. Previously, we have shown that targeting fixed Francisella tularensis bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0525602d32e825787648ef3be1988594
https://doi.org/10.4049/jimmunol.190.supp.54.13
https://doi.org/10.4049/jimmunol.190.supp.54.13
Autor:
Brian Franz, Ying Li, Constantine Bitsaktsis, Bibiana Iglesias, Giang Pham, Sarah Rosa, Edmund Gosselin
Publikováno v:
The Journal of Immunology. 190:54.16-54.16
We have previously shown that intranasal immunization with inactivated Francisella tularensis LVS targeted to FcR induces partial protection against a mucosal challenge with F. tularensis SchuS4 and that this protection is Ab and IFN-γ dependent. Fc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54048da104ba8aa1ff10972e43b87305
https://doi.org/10.4049/jimmunol.190.supp.54.16
https://doi.org/10.4049/jimmunol.190.supp.54.16
Publikováno v:
The Journal of Immunology. 190:54.15-54.15
Dendritic cells play a critical role in the generation of an effective adaptive immune response. This is primarily due to their ability to capture, process, and present Ag to naïve T cells. Administration of Ag-pulsed DCs has proven to be an effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8039f4353c905354edc5d824b1332f6e
https://doi.org/10.4049/jimmunol.190.supp.54.15
https://doi.org/10.4049/jimmunol.190.supp.54.15