Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edmund G. -T. Wee"'
Autor:
Ashley C. Beavis, Edmund G. -T. Wee, Belkis M. Akis Yildirim, Nicola Borthwick, Biao He, Tomáš Hanke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe primary goal of this work is to broaden and enhance the options for induction of protective CD8+ T cells against HIV-1 and respiratory pathogens.MethodsWe explored the advantages of the parainfluenza virus 5 (PIV5) vector for delivery
Externí odkaz:
https://doaj.org/article/94e4c39ba6cf4941a1bc455488fe7801
Autor:
Joanna Roberts, Nicola Winstone, Helen McShane, Julian Sutton, Andrew J. McMichael, Yun-Hsiang Chen, Sandip Patel, Inese Cebere, Mary Brooks, Sarah Rowland-Jones, Tomáš Hanke, Matilu Mwau, Edmund G.-T. Wee, Job J. Bwayo, Lucy Dorrell, C. Schmidt, Priscilla Chikoti, Christopher P. Conlon, Tara S Beattie
The immunogenicities of candidate DNA- and modified vaccinia virus Ankara (MVA)-vectored human immunodeficiency virus (HIV) vaccines were evaluated on their own and in a prime–boost regimen in phase I clinical trials in healthy uninfected individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32743213fc71c5f8033454edfc0b63bf
https://doi.org/10.1099/vir.0.19701-0
https://doi.org/10.1099/vir.0.19701-0
Autor:
Masafumi Takiguchi, Bette T. Korber, Shinichi Oka, Genevieve Clutton, Hayato Murakoshi, Edmund G.-T. Wee, Tomáš Hanke, B Ondondo, Andrew J. McMichael, Sultan Abdul-Jawad, Hiroyuki Gatanaga
An effective human immunodeficiency virus type 1 (HIV-1) vaccine is the best solution for halting the acquired immune deficiency syndrome epidemic. Here, we describe the design and preclinical immunogenicity of T-cell vaccine expressing novel immunog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915fd6f1171f436c739013a3e075c849
Autor:
Anders Fomsgaard, Guang P. Gao, Lasse Vinner, Sylvie Corbet, Claus Nielsen, James M. Wilson, Tomáš Hanke, Hildegund C. J. Ertl, Sandip Patel, Edmund G.-T. Wee
Publikováno v:
Journal of General Virology. 84:203-213
Envelopes of primary R5-tropic human immunodeficiency virus type 1 (HIV-1) isolates may be particularly relevant for vaccine purposes and should be evaluated for immunogenicity in animals including macaques before carrying out human vaccine trials. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53391566dd7d6b2c40ab7ad0cb96656
https://doi.org/10.1099/vir.0.18589-0
https://doi.org/10.1099/vir.0.18589-0
Autor:
Tomáš Hanke, Christina Barnfield, Edmund G.-T. Wee, Rachel V. Samuel, Peter Liljeström, Lena Ågren, Natasha Larke
Publikováno v:
The Journal of general virology. 84(Pt 2)
A novel, experimental subunit human immunodeficiency virus (HIV) vaccine, SFV.HIVA, was constructed. This consists of Semliki Forest virus (SFV), which is a suitable vaccine vector for use in humans, and a passenger gene encoding HIVA, which is an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab3e72f0fea7e4553de237b3a9dcfc0
https://pubmed.ncbi.nlm.nih.gov/12560568
https://pubmed.ncbi.nlm.nih.gov/12560568
Autor:
Tomáš Hanke, Rachel V. Samuel, Maxine Tomlinson, Inese Ceberej, Julian Sutton, Sandip Patel, Andrew J. McMichael, Edmund G.-T. Wee, Matilu Mwau
Publikováno v:
Vaccine. 20(15)
Without going into the details of the devastation that human immunodeficiency virus (HIV) infection causes especially in the developing world, the best hope for changing the course of this epidemic is development of a safe, effective, accessible prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f460a05d906c743a6f945bedf6bfabe
https://pubmed.ncbi.nlm.nih.gov/11983261
https://pubmed.ncbi.nlm.nih.gov/11983261
Publikováno v:
The Journal of general virology. 83(Pt 1)
The minimum requirement for candidate human immunodeficiency virus (HIV) vaccines to enter clinical evaluation in humans should be their demonstrable immunogenicity in non-human primates: induction of antibodies neutralizing primary HIV isolates or e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed955eb4b0da34b6980a5a0625e6d0c9
https://pubmed.ncbi.nlm.nih.gov/11752703
https://pubmed.ncbi.nlm.nih.gov/11752703
Autor:
Edmund G.-T. Wee, Sarah Kempster, Deborah Ferguson, Joanna Hall, Claire Ham, Susan Morris, Alison Crook, Sarah C. Gilbert, Bette Korber, Neil Almond, Tomáš Hanke
Publikováno v:
Vaccines, Vol 12, Iss 9, p 965 (2024)
During the COVID-19 pandemic, antibody-based vaccines targeting the SARS-CoV-2 spike glycoprotein were the focus for development because neutralizing antibodies were associated with protection against the SARS-CoV-2 infection pre-clinically and in hu
Externí odkaz:
https://doaj.org/article/930f60a8a56f41d685369c49147e4604