Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Edmund C. Jenkins"'
Autor:
Paraic A. Kenny, Maryia Barnett, Evelyn Aranda, Hui Liu, Natasha Chandiramani, Kristopher A. Lofgren, Edmund C. Jenkins, Esther A. Peterson
Additional representative examples of Amphiregulin immunostaining in breast cancer specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134e982a6eacb661815f442dbd875e71
https://doi.org/10.1158/0008-5472.22411058.v1
https://doi.org/10.1158/0008-5472.22411058.v1
Autor:
Paraic A. Kenny, Maryia Barnett, Evelyn Aranda, Hui Liu, Natasha Chandiramani, Kristopher A. Lofgren, Edmund C. Jenkins, Esther A. Peterson
Estrogen stimulation promotes epithelial cell proliferation in estrogen receptor (ERα)-positive breast cancer. Many ERα target genes have been enumerated, but the identities of the key effectors mediating the estrogen signal remain obscure. During
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5733b2c648d7903df14893d0e943c957
https://doi.org/10.1158/0008-5472.c.6508142
https://doi.org/10.1158/0008-5472.c.6508142
Autor:
Leilei Wang, Qian Meng, Xinxin Tang, Ting Yin, Jinglu Zhang, Shuting Yang, Xuyun Wang, Haiqian Wu, Qingxi Shi, Edmund C. Jenkins, Nanbert Zhong, Ying Gu
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 54, Iss 5, Pp 527-531 (2015)
Objective: To investigate the clinical efficiency of noninvasive prenatal test (NIPT) identifying fetal chromosomal aneuploidies. Materials and methods: In the present study, 917 women with high-risk pregnancies were invited to participate in an NIPT
Externí odkaz:
https://doaj.org/article/e1744dd6f9a847f08dad663edb542ecc
Publikováno v:
Aging Cancer
Aging and Cancer, Vol 2, Iss 3, Pp 75-81 (2021)
Aging and Cancer, Vol 2, Iss 3, Pp 75-81 (2021)
Aging is a major risk factor of developing breast cancer. Despite the fact that post-menopausal women have lower levels of estrogen, older women have a higher rate of estrogen receptor alpha (ERα) positive breast cancer. Conversely, young women who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33106681a9be84dc8e301f5afaeb099d
https://doi.org/10.1002/aac2.12035
https://doi.org/10.1002/aac2.12035
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Several studies reported that mitochondrial stress induces cytosolic proteostasis. How mitochondrial stress activates proteostasis in the cytosol remains unclear. However, the cross-talk between the mitochondria and cytosolic proteostasis has far rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ce8b3d5377e111ea48ce95ef32ea02
http://europepmc.org/articles/PMC8495152
http://europepmc.org/articles/PMC8495152
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Several studies reported that mitochondrial stress induces cytosolic proteostasis in yeast and C. elegans. Notably, inhibition of mitochondrial translation with doxcycyline decreases the toxicity of β-amyloid aggregates, in a C. elegans. However, ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86686fa197b24c1df022830748bd6597
http://europepmc.org/articles/PMC8379233
http://europepmc.org/articles/PMC8379233
Publikováno v:
Molecular Cancer Therapeutics. 20:P184-P184
The Epidermal Growth Factor Receptor ligand, Amphiregulin, is a key proliferative effector of estrogen receptor signaling in breast cancer and also plays a role in other malignancies. Amphiregulin is a single-pass transmembrane protein proteolyticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dfb3574873e53a096065f95647420c7
https://doi.org/10.1158/1535-7163.targ-21-p184
https://doi.org/10.1158/1535-7163.targ-21-p184
Publikováno v:
Oncogene
We previously reported that the dismutase SOD1 is overexpressed in breast cancer. However, whether SOD1 plays an active role in tumor formation in vivo has never been demonstrated. Further, as luminal cells of normal breast epithelial cells are enric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4b5f291fa517d8f5056f38c822c59
http://europepmc.org/articles/PMC6639133
http://europepmc.org/articles/PMC6639133
Autor:
Xiucui Luo, Qingxi Shi, Yang Gu, Jing Pan, Maofang Hua, Meilin Liu, Ziqing Dong, Meijiao Zhang, Leilei Wang, Ying Gu, Julia Zhong, Xinliang Zhao, Edmund C Jenkins, W Ted Brown, Nanbert Zhong
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79897 (2013)
Preterm birth (PTB) is a live birth delivered before 37 weeks of gestation (GW). About one-third of PTBs result from the preterm premature rupture of membranes (PPROM). Up to the present, the pathogenic mechanisms underlying PPROM are not clearly und
Externí odkaz:
https://doaj.org/article/5495c8e90ba54e4b9d7c9d7e14aa53d4
Autor:
Edmund C. Jenkins, Timothy C. Kenny, Gabriella Casalena, Dazhi Zhao, Giovanni Manfredi, Doris Germain, Maria Gomez, Nagma Shah
Publikováno v:
Endocrinology
Several neurodegenerative disorders are characterized by proteasome dysfunctions leading to protein aggregations and pathogenesis. Since we showed that estrogen receptor alpha (ERα) activates the proteasome, drugs able to stimulate ERα in the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e3ff05330f256ea6bc56ac94ed85eb
https://pubmed.ncbi.nlm.nih.gov/33269387
https://pubmed.ncbi.nlm.nih.gov/33269387