Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Edmund A. Griffin"'
Publikováno v:
Biological psychiatry. 84(3)
BACKGROUND: Methamphetamine (Meth) seeking progressively increases after withdrawal (incubation of Meth craving). We previously demonstrated an association between histone deacetylase 5 (HDAC5) gene expression in rat dorsal striatum and incubation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4238fdb1bd98b0a329167a33ce3ddeb
https://pubmed.ncbi.nlm.nih.gov/29397902
https://pubmed.ncbi.nlm.nih.gov/29397902
Autor:
Yang Li, Denise B. Kandel, Kimberly A. Kempadoo, Luca Colnaghi, Eric R. Kandel, Philippe A. Melas, Royce Zhou, Edmund A. Griffin, Mei-Chen Hu, Peter Mercado, Stacy Stephenson, Kathleen M. Taylor
Publikováno v:
Science Advances
Prior alcohol use increases vulnerability to cocaine addiction by promoting degradation of HDAC4 and HDAC5.
Addiction to cocaine is commonly preceded by experiences with legal or decriminalized drugs, such as alcohol, nicotine, and marijuana. Th
Addiction to cocaine is commonly preceded by experiences with legal or decriminalized drugs, such as alcohol, nicotine, and marijuana. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1dc1d713b08090138a9744e1eb1ddd
https://doi.org/10.1126/sciadv.1701682
https://doi.org/10.1126/sciadv.1701682
Publikováno v:
Science. 286:768-771
Cryptochrome (CRY), a photoreceptor for the circadian clock in Drosophila , binds to the clock component TIM in a light-dependent fashion and blocks its function. In mammals, genetic evidence suggests a role for CRYs within the clock, distinct from h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadca1a097aed0dc77777826e28c8687
https://doi.org/10.1126/science.286.5440.768
https://doi.org/10.1126/science.286.5440.768
Autor:
Christine Schaffran, Yan-You Huang, Eric R. Kandel, Shiqin Xu, Deqi Yin, Amir Levine, Denise B. Kandel, Daniela D. Pollak, Edmund A. Griffin, Bettina Drisaldi
Publikováno v:
Science Translational Medicine. 3
In human populations, cigarettes and alcohol generally serve as gateway drugs, which people use first before progressing to marijuana, cocaine or other illicit substances. To understand the biological basis of the gateway sequence of drug use, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7729ba3f467ad6eb0079ed92195c1443
https://doi.org/10.1126/scitranslmed.3003062
https://doi.org/10.1126/scitranslmed.3003062