Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness.

Autor: Ke R; T-6, Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM, USA., Martinez PP; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Statistics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Smith RL; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Gibson LL; Division of Infectious Diseases and Immunology, Departments of Medicine and Pediatrics, University of Massachusetts Medical School, Worcester, MA, USA., Mirza A; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Conte M; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Gallagher N; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Luo CH; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Jarrett J; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zhou R; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Conte A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Liu T; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Farjo M; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Walden KKO; High-Performance Biological Computing at the Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Rendon G; High-Performance Biological Computing at the Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Fields CJ; High-Performance Biological Computing at the Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Wang L; Veterinary Diagnostic Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Fredrickson R; Veterinary Diagnostic Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Edmonson DC; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Baughman ME; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Chiu KK; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Choi H; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Scardina KR; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Bradley S; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Gloss SL; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Reinhart C; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Yedetore J; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Quicksall J; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Owens AN; Center for Clinical and Translational Research, University of Massachusetts Medical School, Worcester, MA, USA., Broach J; UMass Memorial Medical Center, Worcester, MA, USA.; Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA, USA., Barton B; Division of Biostatistics and Health Services Research, University of Massachusetts Medical School, Worcester, MA, USA.; Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA., Lazar P; Division of Biostatistics and Health Services Research, University of Massachusetts Medical School, Worcester, MA, USA., Heetderks WJ; National Institute for Biomedical Imaging and Bioengineering, Bethesda, MD, USA., Robinson ML; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Mostafa HH; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Manabe YC; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Pekosz A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., McManus DD; Division of Cardiology, University of Massachusetts Medical School, Worcester, MA, USA., Brooke CB; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. cbrooke@illinois.edu.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. cbrooke@illinois.edu.

Publikováno v: Nature microbiology [Nat Microbiol] 2022 May; Vol. 7 (5), pp. 640-652. Date of Electronic Publication: 2022 Apr 28.

Daily sampling of early SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness.

Autor: Ke R, Martinez PP, Smith RL, Gibson LL, Mirza A, Conte M, Gallagher N, Luo CH, Jarrett J, Conte A, Liu T, Farjo M, Walden KKO, Rendon G, Fields CJ, Wang L, Fredrickson R, Edmonson DC, Baughman ME, Chiu KK, Choi H, Scardina KR, Bradley S, Gloss SL, Reinhart C, Yedetore J, Quicksall J, Owens AN, Broach J, Barton B, Lazar P, Heetderks WJ, Robinson ML, Mostafa HH, Manabe YC, Pekosz A, McManus DD, Brooke CB

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Jul 12. Date of Electronic Publication: 2021 Jul 12.