Oxidized thioredoxin-1 restrains the NLRP1 inflammasome.

Autor: Ball DP; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Tsamouri LP; Pharmacology Program of the Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Wang AE; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Huang HC; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Warren CD; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Wang Q; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Edmondson IH; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Griswold AR; Pharmacology Program of the Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY 10065, USA., Rao SD; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Johnson DC; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Bachovchin DA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Pharmacology Program of the Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Publikováno v: Science immunology [Sci Immunol] 2022 Nov 11; Vol. 7 (77), pp. eabm7200. Date of Electronic Publication: 2022 Nov 04.