Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Edmond M. Linossi"'
Autor:
Edmond M. Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J. Calleja, Narelle Keating, Rebecca Feltham, Andrew J. Brooks, Shawn S. Li, Sachdev S. Sidhu, Jeffrey J. Babon, Nadia J. Kershaw, Sandra E. Nicholson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/3771a83e093b48e7a5c69cac8e14f288
Autor:
Edmond M. Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J. Calleja, Narelle Keating, Rebecca Feltham, Andrew J. Brooks, Shawn S. Li, Sachdev S. Sidhu, Jeffrey J. Babon, Nadia J. Kershaw, Sandra E. Nicholson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Suppressor of cytokine signaling (SOCS)2 protein is a key negative regulator of the growth hormone (GH) and Janus kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) signaling cascade. The central SOCS2-Src homology 2 (SH2
Externí odkaz:
https://doaj.org/article/c6fcc1c1f3344e70a63c5dfee1ef2786
Autor:
Jessica Knox, Nicolas Joly, Edmond M. Linossi, José A. Carmona-Negrón, Natalia Jura, Lionel Pintard, William Zuercher, Peter J. Roy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Over one billion people are currently infected with a parasitic nematode. Symptoms can include anemia, malnutrition, developmental delay, and in severe cases, death. Resistance is emerging to the anthelmintics currently used to treat nematod
Externí odkaz:
https://doaj.org/article/d0e282a9e8e24d77b3d9aefd33a45006
Publikováno v:
Structure. 30:1465-1467
TRIB2, a member of the human Tribbles pseudokinase family, functions as a molecular scaffold in diverse signaling pathways. In this issue of Structure, Jamieson et al. report the first high-resolution structure of TRIB2 bound to a nanobody that offer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa016e7c95a01442d0cfab4c9db7623
https://doi.org/10.1016/j.str.2022.10.006
https://doi.org/10.1016/j.str.2022.10.006
Autor:
Lukasz Kedzierski, Michelle D Tate, Alan C Hsu, Tatiana B Kolesnik, Edmond M Linossi, Laura Dagley, Zhaoguang Dong, Sarah Freeman, Giuseppe Infusini, Malcolm R Starkey, Nicola L Bird, Simon M Chatfield, Jeffrey J Babon, Nicholas Huntington, Gabrielle Belz, Andrew Webb, Peter AB Wark, Nicos A Nicola, Jianqing Xu, Katherine Kedzierska, Philip M Hansbro, Sandra E Nicholson
Publikováno v:
eLife, Vol 6 (2017)
Influenza virus infections have a significant impact on global human health. Individuals with suppressed immunity, or suffering from chronic inflammatory conditions such as COPD, are particularly susceptible to influenza. Here we show that suppressor
Externí odkaz:
https://doaj.org/article/1e6a3080baa04d2a86774d6d71b6e598
Autor:
Natalia Jura, Edmond M. Linossi, Eric A. Collisson, Gabriella O Estevam, Masaya Oshima, James S. Fraser
Publikováno v:
Biochemical Society transactions, vol 49, iss 2
Biochem Soc Trans
Biochem Soc Trans
The MET receptor tyrosine kinase (RTK) and its cognate ligand hepatocyte growth factor (HGF) comprise a signaling axis essential for development, wound healing and tissue homeostasis. Aberrant HGF/MET signaling is a driver of many cancers and contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943aaa5cc25c162497c1c6a6a5ed1ebf
https://doi.org/10.1042/bst20200394
https://doi.org/10.1042/bst20200394
Autor:
Sandra E. Nicholson, Rebecca Feltham, Andrew J. Brooks, Nadia J. Kershaw, Colin Hockings, Cyrus Tan, Sachdev S. Sidhu, Kunlun Li, Shawn S.-C. Li, Dale J. Calleja, Farhad Dehkhoda, Narelle Keating, Edmond M. Linossi, Gianluca Veggiani, Jeffrey J. Babon
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Paediatrics Publications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Paediatrics Publications
Suppressor of cytokine signaling (SOCS)2 protein is a key negative regulator of the growth hormone (GH) and Janus kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) signaling cascade. The central SOCS2-Src homology 2 (SH2) domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10a396b70214501e8d9a6216a76721a
https://doi.org/10.1038/s41467-021-26983-5
https://doi.org/10.1038/s41467-021-26983-5
Autor:
Nicolas Joly, Jessica Knox, William J. Zuercher, Natalia Jura, Peter J. Roy, José A. Carmona-Negrón, Lionel Pintard, Edmond M. Linossi
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-88150-6⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-88150-6⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Over one billion people are currently infected with a parasitic nematode. Symptoms can include anemia, malnutrition, developmental delay, and in severe cases, death. Resistance is emerging to the anthelmintics currently used to treat nematode infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a53987534c0611bab53b10006c6f09
https://doi.org/10.1038/s41598-021-88150-6
https://doi.org/10.1038/s41598-021-88150-6
Autor:
Edmond M Linossi, Indu R Chandrashekaran, Tatiana B Kolesnik, James M Murphy, Andrew I Webb, Tracy A Willson, Lukasz Kedzierski, Alex N Bullock, Jeffrey J Babon, Raymond S Norton, Nicos A Nicola, Sandra E Nicholson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70536 (2013)
Suppressor of Cytokine Signaling (SOCS)5 is thought to act as a tumour suppressor through negative regulation of JAK/STAT and epidermal growth factor (EGF) signaling. However, the mechanism/s by which SOCS5 acts on these two distinct pathways is uncl
Externí odkaz:
https://doaj.org/article/1bd4c33ee3a949f28850bca64c3e1c57
Publikováno v:
Growth Factors. 36:104-117
The development and activity of our immune system are largely controlled by the action of pleiotropic cytokines and growth factors, small secreted proteins, which bind to receptors on the surface of immune cells to initiate an appropriate physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6388f1fc4c60274fb538b7109e41c1c7
https://doi.org/10.1080/08977194.2018.1518324
https://doi.org/10.1080/08977194.2018.1518324