Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Edmond Lam"'
Autor:
Bassel Akache, Tyler M. Renner, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Christian Gervais, Jennifer J. Hill, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Anne E. G. Lenferink, Yves Durocher, Michael J. McCluskie
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract Using our strongly immunogenic SmT1 SARS-CoV-2 spike antigen platform, we developed antigens based on the Beta & Delta variants of concern (VOC). These antigens elicited higher neutralizing antibody activity to the corresponding variant than
Externí odkaz:
https://doaj.org/article/d6403fda9ca74d4599cc113bbc9a49d9
Autor:
Bassel Akache, Tyler M. Renner, Anh Tran, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Diana Duque, Julie Haukenfrers, Martin A. Rossotti, Francis Gaudreault, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wangxue Chen, Christian Gervais, Matthew Stuible, Lakshmi Krishnan, Yves Durocher, Michael J. McCluskie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The huge worldwide demand for vaccines targeting SARS-CoV-2 has necessitated the continued development of novel improved formulations capable of reducing the burden of the COVID-19 pandemic. Herein, we evaluated novel protein subunit vaccine
Externí odkaz:
https://doaj.org/article/9618e29b6e8e4f74b75065bea762626c
Autor:
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1043 (2023)
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen. Rabbit hemorrhagic disease virus (RHDV)
Externí odkaz:
https://doaj.org/article/8033a136f9c84c7da76024c305c13447
Autor:
Danielle L. Peters, Carly M. Davis, Greg Harris, Hongyan Zhou, Philip N. Rather, Sabahudin Hrapovic, Edmond Lam, Jonathan J. Dennis, Wangxue Chen
Publikováno v:
Viruses, Vol 15, Iss 3, p 739 (2023)
The world is currently facing a global health crisis due to the rapid increase in antimicrobial-resistant bacterial infections. One of the most concerning pathogens is Acinetobacter baumannii, which is listed as a Priority 1 pathogen by the World Hea
Externí odkaz:
https://doaj.org/article/b6ec9a9c86f34c66b44647e9a245f9f8
Autor:
Eliskander Rabia, Beza Tuga, José de Ondarza, Saleen M. Ramos, Edmond Lam, Sabahudin Hrapovic, Yali Liu, Rajesh Sunasee
Publikováno v:
Polymers, Vol 15, Iss 4, p 865 (2023)
Cationic nanomaterials are promising candidates for the development of effective antibacterial agents by taking advantage of the nanoscale effects as well as other exceptional physicochemical properties of nanomaterials. In this study, carboxylated c
Externí odkaz:
https://doaj.org/article/e0a1cbb18445425da48c63c425a29019
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 2477-2483 (2020)
In this report, chitin and chitosan nanocrystals were used as biomass-based supports for Pd nanoparticles (NPs) used as a heterogeneous catalyst for the Heck coupling reaction. By using a one-pot fabrication method, a Pd salt precursor was directly r
Externí odkaz:
https://doaj.org/article/4e5020f48638405ab53fa89af5f0652a
Publikováno v:
Current Research in Green and Sustainable Chemistry, Vol 5, Iss , Pp 100330- (2022)
Every year, large amounts of marine biomass waste are generated around the globe. In the case of crustaceans, an opportunity is loss to convert these chemically rich streams into important and industrially relevant materials (e.g., chitin, chitosan,
Externí odkaz:
https://doaj.org/article/8dd3d0ff2e214a5fb5ef142d90539008
Autor:
Gerard Agbayani, Yimei Jia, Bassel Akache, Vandana Chandan, Umar Iqbal, Felicity C. Stark, Lise Deschatelets, Edmond Lam, Usha D. Hemraz, Sophie Régnier, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2183-2195 (2020)
Archaeosomes are liposomes formulated using total polar lipids (TPLs) or semi-synthetic glycolipids derived from archaea. Conventional archaeosomes with entrapped antigen exhibit robust adjuvant activity as demonstrated by increased antigen-specific
Externí odkaz:
https://doaj.org/article/3e7ef0b9480d48b5baae17d096234b45
Autor:
Edmond Lam, Usha D. Hemraz
Publikováno v:
Nanomaterials, Vol 11, Iss 7, p 1641 (2021)
In recent years, cellulose nanocrystals (CNCs) have emerged as a leading biomass-based nanomaterial owing to their unique functional properties and sustainable resourcing. Sulfated cellulose nanocrystals (sCNCs), produced by sulfuric acid-assisted hy
Externí odkaz:
https://doaj.org/article/3e9bcdd2b429403ba8d6c98668043145
Autor:
Yimei Jia, Bassel Akache, Gerard Agbayani, Vandana Chandan, Renu Dudani, Blair A. Harrison, Lise Deschatelets, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Felicity C. Stark, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 205 (2021)
Archaeosomes, composed of sulfated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. SLA archaeosomes are a promising adjuvant candidate due to th
Externí odkaz:
https://doaj.org/article/65ffc8ded7204b35b0730b4fdff4a621