Irreducible posterior hip dislocation in the setting of a multifocal displaced pelvic ring injury: A case report

Autor: Mark F. Megerian, Edmond F. O'Donnell, Augustine M. Saiz, Ellen P. Fitzpatrick, Mark A. Lee, Gillian L.S. Soles, Sean T. Campbell

Publikováno v: Trauma Case Reports, Vol 45, Iss , Pp 100836- (2023)

Case report: Traumatic hip dislocations require prompt diagnosis and reduction to preserve the native joint. The classic irreducible posterior hip fracture-dislocation has been described as an immobile, slightly flexed, and internally rotated hip on

Externí odkaz: https://doaj.org/article/09cc9dfb5daf48cda0a93aa8b548d763

Impact of local treatment modality on overall‐ and disease‐specific survival for nonmetastatic pelvic and sacral Ewing sarcoma

Autor: Muhammad Umar Jawad, Brad H. Pollock, Lauren N. Zeitlinger, Edmond F. O'Donnell, Sophia A. Traven, Janai R. Carr‐Ascher, Elysia Alvarez, Marcio H. Malogolowkin, Steven W. Thorpe, R. Lor Randall

Publikováno v: Journal of Surgical Oncology. 126:577-587

The ideal local treatment modality for pelvic and sacral Ewing sarcoma (EWS) is controversial.We present the data from the American College of Surgeon's National Cancer Database (NCDB) and the National Cancer Institute's Surveillance, Epidemiology an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630d7b886aed2e9513656b1febca0385
https://doi.org/10.1002/jso.26922

Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Autor: Hyo Sang Jang, Nancy I. Kerkvliet, Edmond F. O’Donnell, Siva Kumar Kolluri, Daniel F Liefwalker

Publikováno v: Apoptosis. 26:307-322

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic Helix-Loop-Helix/Per-Arnt-Sim) family of proteins. The AhR was cloned and characterized for its role in mediating the toxicity of dioxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7949250a5ad9998a099c3c5880293c62
https://doi.org/10.1007/s10495-021-01666-0

Abstract A022: Targeting of soft tissue sarcoma cancer stem cells improves doxorubicin-sensitivity in vitro

Autor: Edmond F. O'Donnell, Maria Muñoz, Lor Randall, Janai R. Carr-Ascher

Publikováno v: Clinical Cancer Research. 28:A022-A022

Soft tissue sarcomas (STS) are rare tumors encompassing over 70 distinct histopathological subtypes that share a common treatment strategy comprising surgical resection, radiation, and chemotherapy in certain situations. Disease progression and failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69fcc6423afacef3d4ca47e0386dd22e
https://doi.org/10.1158/1557-3265.sarcomas22-a022

Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas

Autor: Steve W Thorpe, William J. Murphy, Ian R. Sturgill, Kevin Stoffel, Alicia A. Gingrich, Sean J. Judge, Logan V Vick, Robert J. Canter, Yue Lyu, May Cho, Robert B. Rebhun, Edmond F O'Donnell, Cordelia Dunai, Alyssa Bellini, Arta M. Monjazeb, Shuai Chen, Morgan A. Darrow

Publikováno v: Journal for immunotherapy of cancer, vol 8, iss 2
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer

PurposeGiven the unmet need for novel immunotherapy in soft tissue sarcoma (STS), we sought to characterize the phenotype and function of intratumoral natural killer (NK) and T cells to identify novel strategies to augment tumor-infiltrating lymphocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbb80badea9765fcd14c1db9a8b34fb
https://escholarship.org/uc/item/3k92s282