Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Edmond CARLIER"'
Autor:
Laure Fronzaroli-Molinieres, Andrzej Bialowas, Norbert Ankri, Célia Gasselin, Philippe Gastrein, Edmond Carlier, Robert H. Cudmore, Emilie Campanac, Dominique Debanne
Publikováno v:
The Journal of Physiology. 589:3753-3773
Non-technical summary We determined here the role of the hyperpolarization-activated cationic (h) current on the temporal organization of hippocampal activity in vitro. In CA1 pyramidal neurons the h-current has three main actions. In addition to set
Autor:
Dominique Debanne, Gisèle Alcaraz, Edmond Carlier, Fahamoe Youssouf, Christelle Gaudioso, Jeffrey J. Clare
Publikováno v:
Biochemical and Biophysical Research Communications. 411:329-334
Mutations in the neuronal Nav1.1 voltage-gated sodium channel are responsible for mild to severe epileptic syndromes. The ubiquitous calcium sensor calmodulin (CaM) bound to rat brain Nav1.1 and to the human Nav1.1 channel expressed by a stably trans
Autor:
Dominique Debanne, Laure Fronzaroli-Molinieres, Maria Jose Perez-Alvarez, Pierre Giraud, Ana del Puerto, Juan José Garrido, Francisco Wandosell, Edmond Carlier
Publikováno v:
Cerebral Cortex
Cerebral Cortex, Oxford University Press (OUP), 2015, 25 (8), pp.2282-2294. ⟨10.1093/cercor/bhu035⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cerebral Cortex, 2015, 25 (8), pp.2282-2294. ⟨10.1093/cercor/bhu035⟩
Cerebral Cortex, Oxford University Press (OUP), 2015, 25 (8), pp.2282-2294. ⟨10.1093/cercor/bhu035⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cerebral Cortex, 2015, 25 (8), pp.2282-2294. ⟨10.1093/cercor/bhu035⟩
© 2014 The Author. All rights reserved. Axon properties, including action potential initiation and modulation, depend on both AIS integrity and the regulation of ion channel expression in the AIS. Alteration of the axon initial segment (AIS) has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59d634b974f3b88100869b44d27c203
https://hal-amu.archives-ouvertes.fr/hal-01766835
https://hal-amu.archives-ouvertes.fr/hal-01766835
Autor:
Edmond Carlier, Dominique Debanne, Laure Fronzaroli-Molinieres, Patrice Déglise, Sami Boudkkazi, Valérie Sourdet, Norbert Ankri
Publikováno v:
The Journal of Physiology. 577:141-154
Brain sodium channels (NaChs) are regulated by various neurotransmitters such as acetylcholine, serotonin and dopamine. However, it is not known whether NaCh activity is regulated by glutamate, the principal brain neurotransmitter. We show here that
Autor:
Michael Seagar, Houcemeddine Othman, Saoussen Mlayah-Bellalouna, Marion Tarbe, Martial A Dufour, Hafedh Mejdoub, Kamel Mabrouk, Jean-Marc Goaillard, Didier Gigmes, Edmond Carlier, Dominique Debanne, Mohamed El Ayeb, Maya Belghazi, Najet Srairi-Abid
Publikováno v:
Toxicon
Toxicon, Elsevier, 2014, 92, pp.14-23. ⟨10.1016/j.toxicon.2014.09.005⟩
Toxicon, 2014, 92, pp.14-23. ⟨10.1016/j.toxicon.2014.09.005⟩
Toxicon, Elsevier, 2014, 92, pp.14-23. ⟨10.1016/j.toxicon.2014.09.005⟩
Toxicon, 2014, 92, pp.14-23. ⟨10.1016/j.toxicon.2014.09.005⟩
International audience; We have purified the AaTX1 peptide from the Androctonus australis (Aa) scorpion venom, previously cloned and sequenced by Legros and collaborators in a venom gland cDNA library from Aa scorpion. AaTX1 belongs to the alpha-Ktx1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c12ae1b7270007c03707250e80d481
https://hal-riip.archives-ouvertes.fr/pasteur-01375056
https://hal-riip.archives-ouvertes.fr/pasteur-01375056
Autor:
Eric DI LUCCIO, Alessandra MATAVEL, Sandrine OPI, Imed REGAYA, Guillaume SANDOZ, Sarrah M'BAREK, Edmond CARLIER, Eric ESTÈVE, Louis CARREGA, Ziad FAJLOUN, Hervé ROCHAT, Erwann LORET, Michel DE WAARD, Jean-Marc SABATIER
Publikováno v:
Biochemical Journal. 361:409-416
Maurotoxin (MTX) is a 34-mer scorpion toxin cross-linked by four disulphide bridges that acts on various K+ channels, including the voltage-gated Shaker B subtype. In the present study, we have investigated over 80h: (1) the time-course of folding of
Autor:
Sylvain Rama, Vincenzo Marra, Andrzej Bialowas, Dominique Debanne, Norbert Ankri, Mickaël Zbili, Laure Fronzaroli-Molinieres, Edmond Carlier
Publikováno v:
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2015, 41 (3), pp.293-304. ⟨10.1111/ejn.12787⟩
European Journal of Neuroscience, 2015, 41 (3), pp.293-304. ⟨10.1111/ejn.12787⟩
European Journal of Neuroscience, Wiley, 2015, 41 (3), pp.293-304. ⟨10.1111/ejn.12787⟩
European Journal of Neuroscience, 2015, 41 (3), pp.293-304. ⟨10.1111/ejn.12787⟩
International audience; Synaptic transmission usually depends on action potentials (APs) in an all-or-none (digital) fashion. Recent studies indicate, however , that subthreshold presynaptic depolarization may facilitate spike-evoked transmission, th
Autor:
Hervé Rochat, Amor Mosbah, Christiane Devaux, Hervé Darbon, Guillaume Sandoz, Sandrine Geib, Pascal Mansuelle, R. Oughideni, Mohamed Fathallah, M. De Waard, Jean-Marc Sabatier, Edmond Carlier, I. Regaya, E. Di Luccio, Ziad Fajloun, Jacques Brocard
Publikováno v:
FEBS Letters. 489:202-207
Maurotoxin (MTX) is a 34-residue toxin that has been isolated from the venom of the chactidae scorpion Scorpio maurus palmatus, and characterized. Together with Pi1 and HsTx1, MTX belongs to a family of short-chain four-disulfide- bridged scorpion to
Autor:
Christiane Devaux, Hervé Darbon, Eric di Luccio, Hervé Rochat, Mohamed Fathallah, Guillaume Sandoz, Michel De Waard, Amor Mosbah, Pascal Mansuelle, Ziad Fajloun, Edmond Carlier, Jean-Marc Sabatier
Publikováno v:
Journal of Biological Chemistry. 275:39394-39402
Maurotoxin (MTX) is a scorpion toxin acting on several K+ channel subtypes. It is a 34-residue peptide cross-linked by four disulfide bridges that are in an “uncommon” arrangement of the type C1-C5, C2-C6, C3-C4, and C7-C8 (versus C1-C5, C2-C6, C
Publikováno v:
Biochemical and Biophysical Research Communications. 274:394-399
The effects of specific CaM kinase II inhibitors were investigated on Na(+) channels from rat cerebellar granule cells. A maximal effect of KN-62 was observed at 20 microM and consisted of an 80% reduction of the peak Na(+) current after only a 10-mi