Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Edmarcia Elisa De Souza"'
Autor:
Yasmin Silva-Santos, Roberta Liberato Pagni, Thais Helena Martins Gamon, Marcela Santiago Pacheco de Azevedo, Mônica Bielavsky, Maria Laura Goussain Darido, Danielle Bruna Leal de Oliveira, Edmarcia Elisa de Souza, Carsten Wrenger, Edson Luiz Durigon, Maria Cecília Rui Luvizotto, Hans Christian Ackerman, Claudio Romero Farias Marinho, Sabrina Epiphanio, Leonardo José Moura Carvalho
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
COVID-19 causes more severe and frequently fatal disease in patients with pre-existing comorbidities such as hypertension and heart disease. SARS-CoV-2 virus enters host cells through the angiotensin-converting enzyme 2 (ACE2), which is fundamental i
Externí odkaz:
https://doaj.org/article/0a80208c429c4258b038df8565cf4881
Autor:
Patrick Y. A. Reinke, Edmarcia Elisa de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karničar, Aleksandra Usenik, Nataša Lindič, Andreja Sekirnik, Viviane Fongaro Botosso, Gláucia Maria Machado Santelli, Josana Kapronezai, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Lizdany Flórez-Álvarez, Danielle Bruna Leal de Oliveira, Edison Luiz Durigon, Paula Roberta Giaretta, Marcos Bryan Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck, Russell Cox, Henry N. Chapman, Christian Betzel, Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa L. Latham, Ana Marcia de Sá Guimarães, Dusan Turk, Carsten Wrenger, Alke Meents
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Several drug screening campaigns identified Calpeptin as a drug candidate against SARS-CoV-2. Initially reported to target the viral main protease (Mpro), its moderate activity in Mpro inhibition assays hints at a second target. Indeed, we s
Externí odkaz:
https://doaj.org/article/959ee7d783844cc0965882267049dc4f
Autor:
Mariângela de Oliveira Silva, Maria Fernanda Castro-Amarante, Alexia Adrianne Venceslau-Carvalho, Bianca da Silva Almeida, Isabela Pazotti Daher, Guilherme Antonio de Souza-Silva, Marcio Massao Yamamoto, Gabriela Koike, Edmarcia Elisa de Souza, Carsten Wrenger, Luís Carlos de Souza Ferreira, Silvia Beatriz Boscardin
Publikováno v:
Vaccines, Vol 12, Iss 4, p 356 (2024)
The unprecedented global impact caused by SARS-CoV-2 imposed huge health and economic challenges, highlighting the urgent need for safe and effective vaccines. The receptor-binding domain (RBD) of SARS-CoV-2 is the major target for neutralizing antib
Externí odkaz:
https://doaj.org/article/b18e25fb932b4d27913f21f4859b0530
Autor:
Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves Franca, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt, Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Stephan Niebling, Angelica Struve Garcia, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Aida Rahmani Mashhour, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Maria Garcia Alai, Dusan Turk, Arwen R. Pearson, Henry N. Chapman, Winfried Hinrichs, Carsten Wrenger, Alke Meents, Christian Betzel
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Three natural phenolic compounds are found to bind to an allosteric site in SARS-CoV-2 papain-like protease and exhibit antiviral activity in vitro, showing potential as starting scaffolds for drug design.
Externí odkaz:
https://doaj.org/article/94a6b8437953446b80663a578e6c235a
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/ecba0c56e3c9453aa98ea4488b0b4e33
Autor:
Lizdany Flórez-Álvarez, Edmarcia Elisa de Souza, Viviane Fongaro Botosso, Danielle Bruna Leal de Oliveira, Paulo Lee Ho, Carlos Pelleschi Taborda, Giuseppe Palmisano, Margareth Lara Capurro, João Renato Rebello Pinho, Helena Lage Ferreira, Paola Minoprio, Eurico Arruda, Luís Carlos de Souza Ferreira, Carsten Wrenger, Edison Luiz Durigon
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Hemorrhagic fever viruses (HFVs) pose a threat to global public health owing to the emergence and re-emergence of highly fatal diseases. Viral hemorrhagic fevers (VHFs) caused by these viruses are mostly characterized by an acute febrile syndrome wit
Externí odkaz:
https://doaj.org/article/22e4f97efec644c296da8bf0aae66662
Autor:
Yasmin da Silva Santos, Thais Helena Martins Gamon, Marcela Santiago Pacheco de Azevedo, Bruna Larotonda Telezynski, Edmarcia Elisa de Souza, Danielle Bruna Leal de Oliveira, Jamille Gregório Dombrowski, Livia Rosa-Fernandes, Giuseppe Palmisano, Leonardo José de Moura Carvalho, Maria Cecília Rui Luvizotto, Carsten Wrenger, Dimas Tadeu Covas, Rui Curi, Claudio Romero Farias Marinho, Edison Luiz Durigon, Sabrina Epiphanio
Publikováno v:
Viruses, Vol 15, Iss 4, p 999 (2023)
Since December 2019, the world has been experiencing the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we now face the emergence of several variants. We aimed to assess the differences between the w
Externí odkaz:
https://doaj.org/article/bbc319626d05447cb74c3e55ce7c473a
Autor:
Andressa Peres de Oliveira, Fernanda Luisa Basei, Priscila Ferreira Slepicka, Camila de Castro Ferezin, Talita D. Melo-Hanchuk, Edmarcia Elisa de Souza, Tanes I. Lima, Valquiria Tiago dos Santos, Davi Mendes, Leonardo Reis Silveira, Carlos Frederico Martins Menck, Jörg Kobarg
Publikováno v:
Proteome Science, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Members of the family of NEK protein kinases (NIMA-related kinases) were described to have crucial roles in regulating different aspects of the cell cycle. NEK10 was reported to take part in the maintenance of the G2/M checkpoint
Externí odkaz:
https://doaj.org/article/bc72c31ac5ed492f96992c9263dba10d
Autor:
Janaina Macedo-da-Silva, Livia Rosa-Fernandes, Vinicius de Morais Gomes, Veronica Feijoli Santiago, Deivid Martins Santos, Catarina Maria Stanischesk Molnar, Bruno Rafael Barboza, Edmarcia Elisa de Souza, Rodolfo Ferreira Marques, Silvia Beatriz Boscardin, Edison Luiz Durigon, Claudio Romero Farias Marinho, Carsten Wrenger, Suely Kazue Nagahashi Marie, Giuseppe Palmisano
Publikováno v:
Viruses, Vol 15, Iss 2, p 290 (2023)
Background: In 2019, the world witnessed the onset of an unprecedented pandemic. By February 2022, the infection by SARS-CoV-2 has already been responsible for the death of more than 5 million people worldwide. Recently, we and other groups discovere
Externí odkaz:
https://doaj.org/article/89b26c93d14346d88e2b24952de8c411
Autor:
Daffiny Sumam de Oliveira, Thales Kronenberger, Giuseppe Palmisano, Carsten Wrenger, Edmarcia Elisa de Souza
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Malaria is a parasitic disease that represents a public health problem worldwide. Protozoans of the Plasmodium genus are responsible for causing malaria in humans. Plasmodium species have a complex life cycle that requires post-translational modifica
Externí odkaz:
https://doaj.org/article/c3931677d7d54f219df38f066ee5471b