Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ediz S Calay"'
Autor:
Christopher F Bell, Daniel C Gibbons, Myriam Drysdale, Helen J Birch, Emily J Lloyd, Vishal Patel, Corinne Carpenter, Katherine Carlson, Ediz S Calay, Arjun Puranik, Tyler E Wagner, John C O'Horo, Raymund R Razonable
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304822 (2024)
BackgroundTo describe outcomes of high-risk patients with coronavirus disease 2019 (COVID-19) treated with sotrovimab, other monoclonal antibodies (mAbs), or antivirals, and patients who did not receive early COVID-19 treatment. We also evaluate the
Externí odkaz:
https://doaj.org/article/40b9c0a553614aab870c96814abcc136
Autor:
Kyeryoung Lee, David Cohn, Zongzhi Liu, Lei Ai, Hunki Paek, Lan Jin, Kalpana Raja, Minghao Li, Xingmin Zhang, Tomi Jun, Mitchell Higashi, William Oh, Ediz S. Calay, Radoslav Savic, Krish Ghosh, Andrew Kasarskis, Tommy Mullaney, Qi Pan, Eric Schadt, Xiaoyan Wang
Publikováno v:
Journal of Clinical Oncology. 40:e13563-e13563
e13563 Background: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease with multiple phenotypes and endotypes and associated with lung cancer development. In this study, we analyzed the clinical features of COPD including various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef55ce684dc03ea192f258437d6535f
https://doi.org/10.1200/jco.2022.40.16_suppl.e13563
https://doi.org/10.1200/jco.2022.40.16_suppl.e13563
Autor:
Kacey J. Prentice, Jani Saksi, Lauren T. Robertson, Grace Y. Lee, Karen E. Inouye, Kosei Eguchi, Alexandra Lee, Ozgur Cakici, Emily Otterbeck, Paulina Cedillo, Peter Achenbach, Anette-Gabriele Ziegler, Ediz S. Calay, Feyza Engin, Gökhan S. Hotamisligil
Publikováno v:
Nature 600, 720–726 (2021)
Nature
Nature
Liberation of energy stores from adipocytes is critical to support survival in times of energy deficit, however, uncontrolled or chronic lipolysis associated with insulin resistance and/or insulin insufficiency, disrupts metabolic homeostasis(1,2). C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e313fef524fb7893a173411f1689acc5
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63799
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63799
Autor:
Idit Ron, Ediz S. Calay, Amir Tirosh, Rinat Livne, Amit Tirosh, Sophie Ron, Moran Rathaus, Abdullah Yalcin, Yankun G. Lee, Gurol Tuncman, Gökhan S. Hotamisligil, Ana Paula Arruda, Neri Minsky
Publikováno v:
Cell Metab
Endoplasmic reticulum stress (ERS) has a pathophysiological role in obesity-associated insulin resistance. Yet, the coordinated tissue response to ERS remains unclear. Increased connexin 43 (Cx43)-mediated intercellular communication has been implica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9ed2125c6831fd7dd6fee22672242d
https://doi.org/10.1016/j.cmet.2021.07.005
https://doi.org/10.1016/j.cmet.2021.07.005
Autor:
Ediz S. Calay, Amir Tirosh, Idit Ron, Iris Shai, Rajesh Garg, Lu Qi, Karen Inouye, Kathryn Claiborn, Michael A.D. Alcala, Gurol Tuncman, Gökhan S. Hotamisligil, Kosei Eguchi, Rinat Livne, Yoriko Heianza, Kenneth Hollander, Moran Rathaus
Publikováno v:
Science Translational Medicine. 11
The short-chain fatty acid propionate is a potent inhibitor of molds that is widely used as a food preservative and endogenously produced by gut microbiota. Although generally recognized as safe by the U.S. Food and Drug Administration, the metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71081d5f65d685fd3d673e4502ea9b2
https://doi.org/10.1126/scitranslmed.aav0120
https://doi.org/10.1126/scitranslmed.aav0120
Autor:
Henrik ten Freyhaus, Zerrin Z. Calay, Ediz S. Calay, Gökhan S. Hotamisligil, Ling Yang, Fahri Saatcioglu, Sara N. Vallerie, Abdullah Yalcin
Publikováno v:
Cell Metabolism. 16:81-89
The six-transmembrane protein Stamp2 plays an important role in metabolically-triggered inflammation and insulin action. However, how and in which target cells Stamp2 regulates inflammatory responses and the physiological consequences remain unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0cc663bfec5809d7ce082cccb936cf
https://doi.org/10.1016/j.cmet.2012.05.009
https://doi.org/10.1016/j.cmet.2012.05.009
Autor:
Kosei Eguchi, Hanna Hailu, Helen Neale, Geofrey Odede, Alexandra Lee, Amir Tirosh, Ediz S. Calay, Gabriel Birrane, Louise Howells, Carl Brendan Doyle, Shauna West, Adrian Moore, Ariel White, Karen Inouye, Gökhan S. Hotamisligil, Daniel John Lightwood, Rachel Garlish, Gurol Tuncman, Motohiro Sekiya, M. Furkan Burak
Publikováno v:
Science Translational Medicine. 7
The lipid chaperone aP2/FABP4 has been implicated in the pathology of many immunometabolic diseases, including diabetes in humans, but aP2 has not yet been targeted for therapeutic applications. aP2 is not only an intracellular protein but also an ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2aa3c865643cc9ad4076c128a1871f
https://doi.org/10.1126/scitranslmed.aac6336
https://doi.org/10.1126/scitranslmed.aac6336
Publikováno v:
Sensors and Actuators B: Chemical. 125:581-588
A previous termsandwich-type antibodynext term microarray was developed for the detection and quantitation of cardiovascular risk markers including C-reactive protein, TNF-α, serum amyloid-A, fatty acid binding protein. In this assay, previous terma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8077f676c2b22afc6c41bb25adf13918
https://doi.org/10.1016/j.snb.2007.03.005
https://doi.org/10.1016/j.snb.2007.03.005
Autor:
Steven P. Gygi, Ryan C. Kunz, Gökhan S. Hotamisligil, Alessandro Arduini, Ediz S. Calay, Suneng Fu, Jason Fan, Ling Yang, Abdullah Yalcin
S-nitrosylation links obesity and cell stress Obesity and other diseases are somehow linked to malfunction of the protein-protecting functions of the endoplasmic reticulum (ER). Yang et al. propose a mechanism by which obesity and associated chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a231c65063daf294b452df379ff64e3
https://europepmc.org/articles/PMC4573582/
https://europepmc.org/articles/PMC4573582/
Autor:
Manoj T. Duraisingh, Christopher Hine, James R. Mitchell, Samantha Lang, Eylul Harputlugil, Dyann F. Wirth, Rick A. Rogers, Pedro Mejia, J. Humberto Treviño-Villarreal, Ediz S. Calay
Publikováno v:
Nature communications
Host nutrition can affect the outcome of parasitic diseases through metabolic effects on host immunity and/or the parasite. Here we show that modulation of mouse immunometabolism through brief restriction of food intake (dietary restriction, DR) prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1a3be70414f30713d035113de68a42
https://doi.org/10.1038/ncomms7050
https://doi.org/10.1038/ncomms7050