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pro vyhledávání: '"Edith Rolser"'
Autor:
Mahindra Makhija, Heike Goebel, Edith Rolser, Torsten Dunkern, Waltraud Burckhard-Boer, Prashant S. Kharkar, Arati Prabhu, Premkumar Arumugam
Publikováno v:
Journal of Computer-Aided Molecular Design. 26:1277-1292
IMPDH (Inosine 5'-monophosphate dehydrogenase) catalyzes a rate-limiting step in the de novo biosynthesis of guanine nucleotides. IMPDH inhibition in sensitive cell types (e.g., lymphocytes) blocks proliferation (by blocking RNA and DNA synthesis as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffa8a5b62455d534b0438dac58a531c
https://doi.org/10.1007/s10822-012-9615-5
https://doi.org/10.1007/s10822-012-9615-5
