Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Edith N. G. Houben"'
Autor:
Merel P. M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberc
Externí odkaz:
https://doaj.org/article/6d89b33110a1441294f5c9186621cb08
Autor:
Vincent J. C. van Winden, Roy Ummels, Sander R. Piersma, Connie R. Jiménez, Konstantin V. Korotkov, Wilbert Bitter, Edith N. G. Houben
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
ABSTRACT Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5. One of the conserved T7S components is the serine protease mycosin (MycP). Strikingly, whereas MycP is essential for secretion, the protease activit
Externí odkaz:
https://doaj.org/article/bf7cb1e658b14d3a818312f43e42cc8a
Autor:
Trang H Phan, Lisanne M van Leeuwen, Coen Kuijl, Roy Ummels, Gunny van Stempvoort, Alba Rubio-Canalejas, Sander R Piersma, Connie R Jiménez, Astrid M van der Sar, Edith N G Houben, Wilbert Bitter
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007247 (2018)
The pathogen Mycobacterium tuberculosis employs a range of ESX-1 substrates to manipulate the host and build a successful infection. Although the importance of ESX-1 secretion in virulence is well established, the characterization of its individual c
Externí odkaz:
https://doaj.org/article/168aa6b95d0e4e7c9b73b8e47bd923a8
The ESX-1 substrate PPE68 has a key function in the ESX-1 mediated secretion inMycobacterium marinum
Autor:
Merel P.M. Damen, Aniek S. Meijers, Esther M. Keizer, Sander R. Piersma, Connie R. Jiménez, Coenraad P. Kuijl, Wilbert Bitter, Edith N. G. Houben
Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such asMycobacterium tuberculosisand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b6ebcf8f61cc643734f6697251d67
https://doi.org/10.1101/2022.06.21.497121
https://doi.org/10.1101/2022.06.21.497121
Autor:
Natalia, Korotkova, Diana, Freire, Trang H, Phan, Roy, Ummels, Christopher C, Creekmore, Timothy J, Evans, Matthias, Wilmanns, Wilbert, Bitter, Annabel H A, Parret, Edith N G, Houben, Konstantin V, Korotkov
Publikováno v:
Molecular microbiology. 94(2)
The growth or virulence of Mycobacterium tuberculosis bacilli depends on homologous type VII secretion systems, ESX-1, ESX-3 and ESX-5, which export a number of protein effectors across membranes to the bacterial surface and environment. PE and PPE p
Publikováno v:
The Journal of Cell Biology
An unbiased photo–cross-linking approach was used to probe the “molecular path” of a growing nascent Escherichia coli inner membrane protein (IMP) from the peptidyl transferase center to the surface of the ribosome. The nascent chain was initia
Autor:
Louis S Ates, Roy Ummels, Susanna Commandeur, Robert van de Weerd, Marion Sparrius, Eveline Weerdenburg, Marina Alber, Rainer Kalscheuer, Sander R Piersma, Abdallah M Abdallah, Moataz Abd El Ghany, Alyaa M Abdel-Haleem, Arnab Pain, Connie R Jiménez, Wilbert Bitter, Edith N G Houben
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005190 (2015)
Mycobacteria possess different type VII secretion (T7S) systems to secrete proteins across their unusual cell envelope. One of these systems, ESX-5, is only present in slow-growing mycobacteria and responsible for the secretion of multiple substrates
Externí odkaz:
https://doaj.org/article/7739a32df2784bf0b05872b1c6e4a5db
Autor:
Musa Sani, Edith N G Houben, Jeroen Geurtsen, Jason Pierson, Karin de Punder, Maaike van Zon, Brigitte Wever, Sander R Piersma, Connie R Jiménez, Mamadou Daffé, Ben J Appelmelk, Wilbert Bitter, Nicole van der Wel, Peter J Peters
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000794 (2010)
The cell envelope of mycobacteria, a group of Gram positive bacteria, is composed of a plasma membrane and a Gram-negative-like outer membrane containing mycolic acids. In addition, the surface of the mycobacteria is coated with an ill-characterized
Externí odkaz:
https://doaj.org/article/a12f7988b59b4c7baf3a0c7c5df3d5ce
Autor:
Wilbert Bitter, Edith N G Houben, Daria Bottai, Priscille Brodin, Eric J Brown, Jeffery S Cox, Keith Derbyshire, Sarah M Fortune, Lian-Yong Gao, Jun Liu, Nicolaas C Gey van Pittius, Alexander S Pym, Eric J Rubin, David R Sherman, Stewart T Cole, Roland Brosch
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000507 (2009)
Externí odkaz:
https://doaj.org/article/1efeb760ec434933a447d9ab9dd83d1d