Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Edith Magnenat"'
Autor:
Francis Vilbois, Alena Hochmann, Jean-Claude Martinou, Bruno Antonsson, Solange Desagher, Sylvie Montessuit, Astrid Osen-Sand, Laurent Journot, Edith Magnenat
Publikováno v:
Molecular Cell. 8(3):601-611
Bid plays an essential role in Fas-mediated apoptosis of the so-called type II cells. In these cells, following cleavage by caspase 8, the C-terminal fragment of Bid translocates to mitochondria and triggers the release of apoptogenic factors, thereb
Autor:
Martin Glauner, Beate E. Kehrel, Kenneth J. Clemetson, Timothy N. C. Wells, Edith Magnenat, Jeannine M. Clemetson, Alexei Navdaev, János Polgár
Publikováno v:
Journal of Biological Chemistry. 276:20882-20889
Aggretin, a potent platelet activator, was isolated from Calloselasma rhodostoma venom, and 30-amino acid N-terminal sequences of both subunits were determined. Aggretin belongs to the heterodimeric snake C-type lectin family and is thought to activa
Autor:
Kenneth J. Clemetson, Jeannine M. Clemetson, Edith Magnenat, Timothy N. C. Wells, János Polgár
Publikováno v:
Journal of Biological Chemistry. 274:29019-29024
We have cloned the platelet collagen receptor glycoprotein (GP) VI from a human bone marrow cDNA library using rapid amplification of cDNA ends with platelet mRNA to complete the 5' end sequence. GPVI was isolated from platelets using affinity chroma
Publikováno v:
Current Genetics. 36:21-28
Two pro-apoptotic proteases, caspase-1 and caspase-3, have been expressed as full-length proteins in the fission yeast Schizosaccharomyces pombe. Both proteins autoprocess to generate the corresponding active enzyme and both are lethal to the yeast c
Publikováno v:
Protein Expression and Purification. 15:202-206
Bax is a proapoptotic ion channel forming protein of the Bcl-2 family. In cells the protein is found in the cytosol and in the mitochondria membrane where it presumably is involved during apoptosis in disruption of the mitochondrial membrane potentia
Autor:
Amanda E. I. Proudfoot, Timothy N. C. Wells, Edith Magnenat, Theodore E. Maione, Terry M. Haley
Publikováno v:
European Journal of Biochemistry. 228:658-664
We have purified platelet factor 4 from porcine platelets and shown that it is glycosylated. The purified protein migrated as a broad band at approximately 14,000 Da, characteristic of glycoproteins. Electrospray mass spectroscopy of the intact prote
Autor:
Timothy N. C. Wells, Kevin B. Bacon, Christine A. Power, Amanda E. I. Proudfoot, Edith Magnenat
Publikováno v:
European Journal of Biochemistry. 221:713-719
In our search for novel chemoattractant factors, we have purified a heparin-binding protein from porcine platelets which is a potent chemoattractant for human neutrophils. The protein has 80 amino acids and a molecular mass of 8597.5Da as measured by
Autor:
Edith Magnenat, Bruno Antonsson, Francis Vilbois, Ioannis Xenarios, Ursula Boschert, Pascale Sattonnet-Roche, Linda Favre-Kontula, Amanda E. I. Proudfoot
Publikováno v:
Proteomics. 8(2)
In order to fully understand biological processes it is essential to identify interactions in protein complexes. There are several techniques available to study this type of interactions, such as yeast two-hybrid screens, affinity chromatography, and
Publikováno v:
Thrombosis and haemostasis. 87(4)
Alboluxin, a potent platelet activator, was purified from Trimeresurus albolabris venom with a mass of 120 kDa non-reduced and, after reduction, subunits of 17 and 24 kDa. Alboluxin induced a tyrosine phosphorylation profile in platelets that resembl
Autor:
Edith Magnenat, Corine Gillieron, Christian Chabert, Marco Muda, Montserrat Camps, Ursula Boschert, Kinsey Maundrell, Steve Arkinstall, Jean-Claude Martinou, Elizabeth Vial-Knecht, Bruno Antonsson
Publikováno v:
The Journal of biological chemistry. 272(40)
We have studied the phosphorylation of the Bcl-2 family of proteins by different mitogen-activated protein (MAP) kinases. Purified Bcl-2 was found to be phosphorylated by the c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) p54-SAPK