Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Edith M. Sampson"'
Autor:
Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M. Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S. Ticsa, Aaron S. Gomez, Isabela Caicedo, Upal Bose, Paul J. Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C. Foster, Richard Salvi, Shinichi Someya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
A common complication of cisplatin-based chemotherapy is hearing loss. Here, Park et al. show that glutathione transferase α4 (GSTA4) contributes to reducing cisplatin toxicity in the inner ear of female mice by removing 4-hydroxynonenal (4-HNE).
Externí odkaz:
https://doaj.org/article/a4b9d8b940ff4c42bbb2c14bdd319a1a
Autor:
Aaron S. Gomez, Yong Hwan Kim, Thomas C. Foster, Mi-Jung Kim, Christina Rothenberger, Upal Bose, Richard Salvi, Isabela Caicedo, Karessa White, Senthilvelan Manohar, Hyo-Jin Park, Dalian Ding, Masaru Tanokura, Edith M. Sampson, Maria S. Ticsa, Paul J. Linser, Ashok V. Kumar, Shinichi Someya, Takuya Miyakawa, Chul Han, Kevin Boyd
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Cisplatin is one of the most widely used chemotherapeutic drugs for the treatment of cancer. Unfortunately, one of its major side effects is permanent hearing loss. Here, we show that glutathione transferase α4 (GSTA4), a member of the Phase II deto
Autor:
David I. Shapiro-Ilan, Hilal Erdoğan, Fatma Kaplan, Edwin E. Lewis, Edith M. Sampson, Glen Stevens, Karl Cameron Schiller, Julie Giurintano, Cedric Torres, Jiayi Sun, Amaleah Mirti, Abigail Perret-Gentil
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Ascaroside pheromones stimulate dispersal, a key nematode behavior to find a new food source. Ascarosides produced by entomopathogenic nematodes (EPNs) drive infective juvenile (IJ) emergence from consumed cadavers and dispersal in soil. Without asca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f2f5111c25f33e3a9b84276d5c08cd
http://hdl.handle.net/11452/30083
http://hdl.handle.net/11452/30083
Autor:
Joan A. Whitlock, Ann Progulske-Fox, Edith M. Sampson, Evan A. Murrell, Leticia Reyes, Priscilla L. Phillips
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207295 (2018)
PLoS ONE
PLoS ONE
The oral obligate anaerobe Porphyromonas gingivalis possesses a small conserved transcript PG_RS02100 of unknown function we previously identified using small RNA-seq analysis as expressed during logarithmic growth. In this study, we sought to determ
Autor:
Priscilla L. Phillips, John I. Azeke, Edith M. Sampson, Stephen C. Davis, Qingping Yang, Gregory S. Schultz, Afifa Hamad
Publikováno v:
International Wound Journal
An ex vivo porcine skin explant biofilm model that preserves key properties of biofilm attached to skin at different levels of maturity (0–3 days) was used to assess the efficacy of commercially available antimicrobial dressings and topical treatme
Autor:
Ann Progulske-Fox, Shouguang Jin, Patrick J. Antonelli, Gregory S. Schultz, Edith M. Sampson, Qingping Yang, Priscilla L. Phillips
Publikováno v:
Wound Repair and Regeneration. 21:704-714
Bacterial biofilms have been proposed to be a major factor contributing to the failure of chronic wounds to heal because of their increased tolerance to antimicrobial agents and the prolonged inflammation they cause. Phenotypic characteristics of bac
Publikováno v:
Otolaryngology–Head and Neck Surgery. 142:405-408
Carbomethylcellulose (CMC) foam has been widely adopted to promote hemostasis and healing in sinus surgery. There has been interest in the use of CMC in middle ear surgery. The purpose of this study was to evaluate the safety and efficacy of CMC foam
Publikováno v:
American Journal of Otolaryngology. 30:367-370
Purpose Ossicular chain reconstruction may be complicated by prosthesis extrusion. As prostheses are commonly placed in middle ears contaminated with biofilm-forming bacteria, such as Pseudomonas aeruginosa (PA), extrusion may be caused by developmen
Publikováno v:
The Laryngoscope. 120:178-182
Objectives/Hypothesis: Iatrogenic semicircular canal (SC) transection during mastoidectomy for chronic otitis media often leads to profound hearing loss. AM-111, an apoptosis inhibitor, has been shown to mitigate hearing loss resulting from a variety
Publikováno v:
Int Wound J
Excessive levels of matrix metalloproteinases (MMPs) are present in chronic wounds preventing wound closure. Reducing detrimental components may be key in healing chronic wounds. Elta Protease-containing wound dressings have been observed clinically