Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Edith M Gardiner"'
Autor:
Claire J Watson, W Joyce Tang, Maria F Rojas, Imke A K Fiedler, Ernesto Morfin Montes de Oca, Andrea R Cronrath, Lulu K Callies, Avery Angell Swearer, Ali R Ahmed, Visali Sethuraman, Sumaya Addish, Gist H Farr, Arianna Ericka Gómez, Jyoti Rai, Adrian T Monstad-Rios, Edith M Gardiner, David Karasik, Lisa Maves, Bjorn Busse, Yi-Hsiang Hsu, Ronald Young Kwon
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010496 (2022)
Bone and muscle are coupled through developmental, mechanical, paracrine, and autocrine signals. Genetic variants at the CPED1-WNT16 locus are dually associated with bone- and muscle-related traits. While Wnt16 is necessary for bone mass and strength
Externí odkaz:
https://doaj.org/article/5c1e0f2009e24bea8e2128b9e43705bc
Autor:
Sundar Srinivasan, Danica Balsiger, Phillipe Huber, Brandon J Ausk, Steven D Bain, Edith M Gardiner, Ted S Gross
Publikováno v:
JBMR Plus, Vol 3, Iss 5, Pp n/a-n/a (2019)
Abstract Nearly all exogenous loading models of bone adaptation apply dynamic loading superimposed upon a time invariant static preload (SPL) in order to ensure stable, reproducible loading of bone. Given that SPL may alter aspects of bone mechanotra
Externí odkaz:
https://doaj.org/article/19809fc1f19446d38dac9cf82290ac51
Autor:
Leah E Worton, Edith M Gardiner, Ronald Y Kwon, Leah M Downey, Brandon J Ausk, Steven D Bain, Ted S Gross
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
At sufficient dose, intramuscular injection of Botulinum toxin A causes muscle wasting that is physiologically consistent with surgical denervation and other types of neuromuscular dysfunction. The aim of this study was to clarify early molecular and
Externí odkaz:
https://doaj.org/article/ee7fafa5d5b9490b868f4939f5190ce7
Autor:
Sundar Srinivasan, Dewayne Threet, Leah E Worton, Brandon J Ausk, Steven D Bain, Edith M Gardiner, Ronald Y Kwon, Ted S Gross
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84868 (2014)
Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation wi
Externí odkaz:
https://doaj.org/article/d26bbf6752e7440a8222defa29f2697d
Autor:
Leah E Worton, Brandon J Ausk, Leah M Downey, Steven D Bain, Edith M Gardiner, Sundar Srinivasan, Ted S Gross, Ronald Y Kwon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74205 (2013)
Bone has long been established to be a highly mechanosensitive tissue. When subjected to mechanical loading, bone exhibits profoundly different anabolic responses depending on the temporal pattern in which the stimulus is applied. This phenomenon has
Externí odkaz:
https://doaj.org/article/9c0c15401563429c86f952ae64e9efca
Autor:
Leah E. Worton, Sundar Srinivasan, DeWayne Threet, Brandon J. Ausk, Phillipe Huber, Ronald Y. Kwon, Steven D. Bain, Ted S. Gross, Edith M. Gardiner
Publikováno v:
JBMR Plus, Vol 7, Iss 2, Pp n/a-n/a (2023)
Abstract The anabolic response of aged bone to skeletal loading is typically poor. Efforts to improve mechanotransduction in aged bone have met with limited success. This study investigated whether the bone response to direct skeletal loading is impr
Externí odkaz:
https://doaj.org/article/58641746352440d382434d6b4439819d
Autor:
Leah E. Worton, Sundar Srinivasan, DeWayne Threet, Brandon J. Ausk, Phillipe Huber, Ronald Y. Kwon, Steven D. Bain, Ted S. Gross, Edith M. Gardiner
Publikováno v:
JBMR Plus. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf85e25206e952ec61b0d8ac6f265bdc
https://doi.org/10.1002/jbm4.10712
https://doi.org/10.1002/jbm4.10712
Autor:
Claire J. Watson, W. Joyce Tang, Maria F. Rojas, Imke A.K. Fiedler, Ernesto Morfin Montes de Oca, Andrea R. Cronrath, Lulu K. Callies, Avery Angell Swearer, Ali R. Ahmed, Visali Sethuraman, Sumaya Addish, Gist H. Farr, Arianna E. Gomez, Jyoti Rai, Adrian T. Monstad-Rios, Edith M. Gardiner, David Karasik, Lisa Maves, Bjorn Busse, Yi-Hsiang Hsu, Ronald Young Kwon
Bone and muscle interact through developmental, mechanical, paracrine, and autocrine signals. Genetic variants at the CPED1-WNT16 locus are dually associated with bone- and muscle-related traits. While Wnt16 is necessary for bone mass and strength, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cef41a6044d6d8325b1fc36c87fad2
https://doi.org/10.1101/2021.08.12.456120
https://doi.org/10.1101/2021.08.12.456120
Autor:
Thomas J. Gonda, Elisabeth J Smith, Simon C. Barry, Leah E. Worton, Yan-Chuan Shi, Edith M. Gardiner, Jonathan P. Whitehead
Publikováno v:
Journal of Cellular Biochemistry. 118:2141-2150
The importance of Wnt pathway signaling in development of bone has been well established. Here we investigated the role of a known Wnt target, ENC1 (ectodermal-neural cortex 1; NRP/B), in osteoblast differentiation. Enc1 expression was detected in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fbfb0d1e42b33952cd15d31fc877858
https://doi.org/10.1002/jcb.25851
https://doi.org/10.1002/jcb.25851
Autor:
Brandon J. Ausk, Ted S. Gross, Edith M. Gardiner, Leah E. Worton, Steven D. Bain, Ronald Y. Kwon, Leah M. Downey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
At sufficient dose, intramuscular injection of Botulinum toxin A causes muscle wasting that is physiologically consistent with surgical denervation and other types of neuromuscular dysfunction. The aim of this study was to clarify early molecular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098c8a7cf8402569cd96a846efa842ab
http://europepmc.org/articles/PMC6235354
http://europepmc.org/articles/PMC6235354