Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Edith Lord"'
Autor:
Scott Gerber, Taylor Uccello, Maggie Lesch, Sarah Kintzel, Lauren Gradzewicz, Lillia Lamrous, Shawn Murphy, Fergal Fleming, Bradley Mills, Joseph Murphy, Angela Hughson, Jesse Garrett-Larsen, Haoming Qiu, Michael Drage, Jian Ye, Nicholas Gavras, David Keeley, Tanzy Love, Elizabeth Repasky, Edith Lord, David Linehan
Rectal cancer ranks as the second leading cause of cancer-related deaths. Neoadjuvant therapy for rectal cancer patients often results in individuals that respond well to therapy and those that respond poorly, requiring life-altering excision surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a31e9b1c60ad54cf10c4dc0bf040f48
https://doi.org/10.21203/rs.3.rs-2767780/v1
https://doi.org/10.21203/rs.3.rs-2767780/v1
Autor:
John, Puskas, Denise, Skrombolas, Abigail, Sedlacek, Edith, Lord, Mark, Sullivan, John, Frelinger
Publikováno v:
Immunology. 133(2)
The ability to alter the cytokine microenvironment has the potential to shape immune responses in many physiological settings, including the immunotherapy of tumours. We set out to develop a general approach in which cytokines could be functionally a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15aca4b3379f23dd90a9763de8784ee4
https://pubmed.ncbi.nlm.nih.gov/21426339
https://pubmed.ncbi.nlm.nih.gov/21426339
Autor:
Selene Meza-Perez, Aaron Silva-Sanchez, Maria de la Luz Garcia-Hernandez, Uma Mudunuru, Javier Rangel-Moreno, Scott Simpler, Stacey Sinclair, Casey Weaver, Trenton Schoeb, Edith Lord, Troy Randall
Publikováno v:
The Journal of Immunology. 194:210.6-210.6
The omentum is an adipose tissue that contains milky spots (MS). The MS are similar to secondary lymphoid organs and can generate B and T cell immune responses to peritoneal antigens. Additionally, omentum CD4+CD25+FoxP3+ T regulatory cells (Tregs) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be06ce114bee2cde6e80c9a8561a85fd
https://doi.org/10.4049/jimmunol.194.supp.210.6
https://doi.org/10.4049/jimmunol.194.supp.210.6
Publikováno v:
The Journal of Immunology. 190:171.15-171.15
Pro-inflammatory cytokines required for immunity against non-self, such as interferons (IFNs), are expressed at the maternal-fetal interface during normal pregnancy. However, neither the placental cell targets nor the functions of these cytokines hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8738efc9009ecbb467ccc4f9b91eb14
https://doi.org/10.4049/jimmunol.190.supp.171.15
https://doi.org/10.4049/jimmunol.190.supp.171.15
Publikováno v:
The Journal of Immunology. 190:130.29-130.29
The United States continues to be a prime target for attack by terrorist organizations in which nuclear detonation or dispersal of radiological material are legitimate threats. These types of attacks could result in devastating consequences to a mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de5db71977b6784cea7a1393104bd6dd
https://doi.org/10.4049/jimmunol.190.supp.130.29
https://doi.org/10.4049/jimmunol.190.supp.130.29
Autor:
Denise Skrombolas, John Puskas, Abigail Sedlacek, Wade Narrow, Michael Mastrangelo, William Bowers, Edith Lord, John Frelinger
Publikováno v:
The Journal of Immunology. 188:46.17-46.17
Cytokines are being used for tumor immunotherapy, but when delivered systemically, negative side effects limit their utility. To mitigate these side effects but maintain their anti-tumor effects, we have constructed a panel of fusion proteins (FPs) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c525d8d6954d602910ad9fd32af0592
https://doi.org/10.4049/jimmunol.188.supp.46.17
https://doi.org/10.4049/jimmunol.188.supp.46.17
Publikováno v:
The Journal of Immunology. 188:162.22-162.22
Tumor cell metastasis to the peritoneal cavity (PC) is a serious concern for many cancers, including ovarian and colon tumors. Upon introduction to the PC, tumor cells bind to the omentum, a tissue comprised of adipose embedded with organized immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840696dc7bfd4db40572702f5d1ac89d
https://doi.org/10.4049/jimmunol.188.supp.162.22
https://doi.org/10.4049/jimmunol.188.supp.162.22
Publikováno v:
The Journal of Immunology. 188:46.3-46.3
A new paradigm has emerged demonstrating that the immune system mediates many of the anti-tumor effects of radiation therapy (RT). RT continues to be a cornerstone in the treatment for many cancers, unfortunately not all individuals respond effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a2d1989eadc86e9b8dd18328007b91
https://doi.org/10.4049/jimmunol.188.supp.46.3
https://doi.org/10.4049/jimmunol.188.supp.46.3
Publikováno v:
The Journal of Immunology. 188:162.33-162.33
Interferon alpha (IFNα) has been FDA-approved for treatment of high-risk melanoma since 1995. Besides having direct antitumor effects, IFNα and IFNβ, the other major type I IFN (IFN-I), have been found to act through enhancing multiple pathways wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2409dd749913130585850aeae6e1a532
https://doi.org/10.4049/jimmunol.188.supp.162.33
https://doi.org/10.4049/jimmunol.188.supp.162.33
Publikováno v:
The Journal of Immunology. 186:165.31-165.31
Tumor metastasis to the peritoneal cavity is often observed in patients with primary ovarian cancer as well as resected colon cancers. Metastatic cells frequently attach to the omentum, a peritoneal adipose tissue that contains many immune aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df5fb368833b897eb3dfc9fd308e04d9
https://doi.org/10.4049/jimmunol.186.supp.165.31
https://doi.org/10.4049/jimmunol.186.supp.165.31