Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edith Janssen"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24102 (2011)
As single agents, ABT-263 and ABT-737 (ABT), molecular antagonists of the Bcl-2 family, bind tightly to Bcl-2, Bcl-xL and Bcl-w, but not to Mcl-1, and induce apoptosis only in limited cell types. The compound 2-deoxyglucose (2DG), in contrast, partia
Externí odkaz:
https://doaj.org/article/30e63c6b75be4ad58bcb8cb3ced104f4
Autor:
Hannah Newton, Vaibhavkumar S Gawali, Ameet A Chimote, Maria Lehn, Sarah Palackdharry, David Hildeman, Edith Janssen, Trisha Wise-Draper, Laura Conforti
Publikováno v:
The Journal of Immunology. 204:165.41-165.41
Head and neck cancer (HNC) is the sixth most common cancer worldwide with a five-year survival of 50%. Immunotherapy is emerging as a promising treatment modality in HNC. Pembrolizumab, an anti-PD-1 antibody, is an immunotherapy currently approved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d86e68f58d424e115212288248d18bb7
https://doi.org/10.4049/jimmunol.204.supp.165.41
https://doi.org/10.4049/jimmunol.204.supp.165.41
Autor:
J André Grotenhuis, Willemijn F. M. van Nuenen, Joost de Vries, Gert P. Westert, Edith Janssen, Mariana P. Duarte Conde, Hieronymus D. Boogaarts, Rogier Donders, Ronald H. M. A. Bartels
Publikováno v:
Acta Neurochirurgica, 156, 9, pp. 1663-7
Acta Neurochirurgica, 156, 1663-7
Acta Neurochirurgica, 156, 1663-7
Contains fulltext : 137088.pdf (Publisher’s version ) (Closed access) BACKGROUND: Several studies have included different co-morbid conditions in prediction models for stroke patients. For subarachnoid haemorrhage (SAH), it is not known whether the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28110462843f61b3664b8f5ff0b7ef61
https://doi.org/10.1007/s00701-014-2160-3
https://doi.org/10.1007/s00701-014-2160-3
Autor:
Vaibhavkumar Shantaram Gawali, Ameet A Chimote, Martina Chirra, Edith Janssen, Trisha Wise-Draper, Laura Conforti
Publikováno v:
The Journal of Immunology. 202:195.34-195.34
Immunotherapy offers promising results in head and neck cancer (HNC) albeit it faces the problem of high resistance. PD1 (programmed death receptor-1) and its ligand (PD-L1/PD-L2) interaction reduces T cell receptor (TCR)-stimulated Ca2+ fluxes. Ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7a54e0c16ba85704a47f6d77cfcb478
https://doi.org/10.4049/jimmunol.202.supp.195.34
https://doi.org/10.4049/jimmunol.202.supp.195.34
Autor:
Anna Sliz, Kathryn C.S. Locker, Kristin Lampe, Alzbeta Godarova, David R Plas, Edith Janssen, Helen Jones, Andrew B Herr, Kasper Hoebe
Publikováno v:
The Journal of Immunology. 202:181.26-181.26
The Grb2-associated binding protein 3 (Gab3) is a scaffolding protein that belongs to the Grb2-assocated binding family of proteins along with Gab1 and Gab2. Gab3 is expressed exclusively in immune cells including NK cells, CD8+T cells, mast cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf65e87bf8d98fb98b863dc78d91770d
https://doi.org/10.4049/jimmunol.202.supp.181.26
https://doi.org/10.4049/jimmunol.202.supp.181.26
Autor:
Edith Janssen, Robert Thacker, Hesham M Shehata, Celine Silva Lages, Cassandra Hennies, Maria Lehn, Claire Chougnet
Publikováno v:
The Journal of Immunology. 196:116.13-116.13
Impaired functionality of dendritic cells (DCs) significantly contributes to decreased adaptive immune responses in aged hosts. The expression of MHC-peptide on the DC surface is the critical first step in T cell priming, but few studies have address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a462d35d551b55e9af3907f7e94dca
https://doi.org/10.4049/jimmunol.196.supp.116.13
https://doi.org/10.4049/jimmunol.196.supp.116.13
Autor:
Koichi Tabeta, Mann Navjiwan, Edith Janssen, Bruce Beutler, Xin Du, Timothy D. Bigby, Karine Crozat
Publikováno v:
Blood. 104:313-313
Pinkie is a recessive ENU-induced mutation, homozygotes develop premature graying and subsequently, progressive alopecia. Histologically, the skin is characterized by the destruction of hair follicle architecture, formation of dermal cysts and appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48540b6eb9f86fe9d17b60ab7449aecd
https://doi.org/10.1182/blood.v104.11.313.313
https://doi.org/10.1182/blood.v104.11.313.313