Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Edith Gössnitzer"'
Autor:
Elisabeth Plhak, Christopher Pichler, Björn Dittmann-Schnabel, Edith Gößnitzer, Reingard M. Aigner, Susanne Stanzel, Herbert Kvaternik
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1138 (2023)
[68Ga]Ga-FAPI-46 is a radiolabelled fibroblast activation protein inhibitor that selectively binds to fibroblast activation protein (FAP), which is overexpressed by cancer-associated fibroblasts (CAFs) in the tumour microenvironment. In recent years,
Externí odkaz:
https://doaj.org/article/2e3619284f614597914cfc14a6869b6d
Publikováno v:
Molecules, Vol 28, Iss 2, p 577 (2023)
Many radioactive PSMA inhibitory substances have already been developed for PET diagnostics and therapy of prostate cancer. Because PET radionuclides and instrumentation may not be available, technetium-99 m labelled tracers can be considered as a di
Externí odkaz:
https://doaj.org/article/671e7cd51cb24f85aa1dffaac8f4d2d1
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 96 (2022)
Dopaminergic transporter (DAT) imaging with single photon emission computed tomography (SPECT) is used to diagnose Parkinson’s disease and to differentiate it from other neurodegenerative disorders without presynaptic dopaminergic dysfunction. The
Externí odkaz:
https://doaj.org/article/bdbaa1920262445d85dc3eb38c896264
Publikováno v:
Scientia Pharmaceutica
Volume 72
Issue 2
Pages 92-103
Scientia Pharmaceutica; Volume 72; Issue 2; Pages: 109-120
Pages 109-120
Volume 72
Issue 2
Pages 92-103
Scientia Pharmaceutica; Volume 72; Issue 2; Pages: 109-120
Pages 109-120
Erhitzen von Amiloridhydrochlorid (1 • Hcl) in Acetatpuffer pH 4.6 führte zu Amiloridacetat (1 • AcOH), dem Pyrazindiamin 6 und dem Acylureid 7. Das Pteridinon 3 wurde beim Erhitzen von 1 • Hcl in DMF unter Rückfluß erhalten.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf73fb12254684126ff9befc4e36956
https://doi.org/10.3797/scipharm.aut-04-10
https://doi.org/10.3797/scipharm.aut-04-10
Autor:
Asbjörn Punkenhofer, Edith Gößnitzer
Publikováno v:
Monatshefte f�r Chemie / Chemical Monthly. 134:1271-1282
The synthesis of 1,2,6,10b,11,12-hexahydro-5H-imidazo[1′,2′:1,2]pyrimido[4,3-a]isoquinolines representing new types of 8,13,15-triazasteroids is described. The tetracyclic title compounds were prepared from 4-(2-hydroxyalkylamino)tetrahydro-2H-py
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70954d4361872a0f0a3dcba460a3fc0f
https://doi.org/10.1007/s00706-003-0038-9
https://doi.org/10.1007/s00706-003-0038-9
Publikováno v:
Archiv der Pharmazie. 336:336-344
4-alkylamino-and 4-alkenylamino-9-hydroxy-1, 6, 7, 11b-tetrahydro-2H-pyrimido[4, 3-a]isoquinolines were designed as inhibitory tricyclic triaza-analogues of carbocationic high energy intermediates (HEI) of enzymes involved in fungal ergosterol biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad69c99e20f91011efb78a3d67a73bfa
https://doi.org/10.1002/ardp.200300774
https://doi.org/10.1002/ardp.200300774
Publikováno v:
European Journal of Pharmaceutical Sciences. 19:151-164
A series of N4-alkyl-1,6,7,11b-tetrahydro-2H-pyrimido[4,3-a]isoquinolinamine hydroiodides with triazasterol-related structures was designed and synthesized to mimic, as stable analogues, native high energy intermediates (HEI) of ergosterol biosynthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::322e7af5f119372a61b8631398a06cc3
https://doi.org/10.1016/s0928-0987(03)00086-1
https://doi.org/10.1016/s0928-0987(03)00086-1
Autor:
Edith Gößnitzer, Asbjörn Punkenhofer
Publikováno v:
Monatshefte f�r Chemie / Chemical Monthly. 134:909-927
Various routes for an effective synthesis of 1,6,7,11b-tetrahydro-2H-pyrimido[4,3-a]isoquinolin-4-amine and its 9-methoxy derivative, which were designed as tricyclic triaza-analogues with stable positive charge to mimic carbocationic high energy int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c7dc30f18eae0a85196c5de75fdcf50
https://doi.org/10.1007/s00706-002-0559-7
https://doi.org/10.1007/s00706-002-0559-7
Publikováno v:
Archiv der Pharmazie. 335:535-546
A series of N-alkyl-N'-(phenethyl- and cyclohexenylethyl) guanidines and N(2)- and N(2), 4-substituted imidazolin-2-amine hydrochlorides with triazasterol-related structures was designed and synthesized as stable analogues to mimic high energy interm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb3333aba9adc2e8099527fa66123e4
https://doi.org/10.1002/ardp.200290007
https://doi.org/10.1002/ardp.200290007
Publikováno v:
Monatshefte f?r Chemie / Chemical Monthly. 133:1177-1185
Novel N-(3-oxobutyl)-hydroxy- and acetoxypyrido[2,3-d]pyridazinones were synthesized and tested in vivo for their sedative and anticonvulsant activity. The Michael-type reaction of quinolinic acid hydrazide and methyl vinyl ketone afforded a mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1446cd374fedc9f4e8a82d23c99c521
https://doi.org/10.1007/s00706-002-0473-z
https://doi.org/10.1007/s00706-002-0473-z