Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Edith, Slot"'
1
Akademický článek
Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes
Autor: Paula Martinez-Sanz, Adrien R. G. Laurent, Edith Slot, Mark Hoogenboezem, Nikolina Bąbała, Robin van Bruggen, Anthony Rongvaux, Richard A. Flavell, Godelieve A. M. Tytgat, Katka Franke, Hanke L. Matlung, Taco W. Kuijpers, Derk Amsen, Julien J. Karrich
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionMISTRG mice have been genetically modified to allow development of a human myeloid compartment from engrafted human CD34+ haemopoietic stem cells, making them particularly suited to study the human innate immune system in vivo. Here, we c
Externí odkaz: https://doaj.org/article/6f2a3ef6081c4018ae68e848da1ea48c
Zobrazit plný text záznamu
2
Akademický článek
Bone Marrow Harbors a Unique Population of Dendritic Cells with the Potential to Boost Neutrophil Formation upon Exposure to Fungal Antigen
Autor: Marieke Goedhart, Edith Slot, Maria F. Pascutti, Sulima Geerman, Timo Rademakers, Benjamin Nota, Stephan Huveneers, Jaap D. van Buul, Katherine C. MacNamara, Carlijn Voermans, Martijn A. Nolte
Publikováno v: Cells, Vol 11, Iss 1, p 55 (2021)
Apart from controlling hematopoiesis, the bone marrow (BM) also serves as a secondary lymphoid organ, as it can induce naïve T cell priming by resident dendritic cells (DC). When analyzing DCs in murine BM, we uncovered that they are localized aroun
Externí odkaz: https://doaj.org/article/30d8e79930cc4f6ba9574ea522c5a93a
Zobrazit plný text záznamu
3
Bone Marrow Harbors a Unique Population of Dendritic Cells with the Potential to Boost Neutrophil Formation upon Exposure to Fungal Antigen
Autor: Marieke Goedhart, Edith Slot, Maria F. Pascutti, Sulima Geerman, Timo Rademakers, Benjamin Nota, Stephan Huveneers, Jaap D. van Buul, Katherine C. MacNamara, Carlijn Voermans, Martijn A. Nolte
Publikováno v: Cells, Vol 11, Iss 55, p 55 (2022)
Cells
Cells, 11(1):55. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(1):55. MDPI Multidisciplinary Digital Publishing Institute
Cells; Volume 11; Issue 1; Pages: 55
Apart from controlling hematopoiesis, the bone marrow (BM) also serves as a secondary lymphoid organ, as it can induce naïve T cell priming by resident dendritic cells (DC). When analyzing DCs in murine BM, we uncovered that they are localized aroun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29acab0c0f66ca5ee70b6a04a9be6b7a
https://www.mdpi.com/2073-4409/11/1/55
Zobrazit plný text záznamu
4
Akademický článek
Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.
Autor: Maria Fernanda Pascutti, Sulima Geerman, Edith Slot, Klaas P J M van Gisbergen, Louis Boon, Ramon Arens, Rene A W van Lier, Monika C Wolkers, Martijn A Nolte
Publikováno v: PLoS Pathogens, Vol 11, Iss 3, p e1004675 (2015)
Chronic infections are characterized by the inability to eliminate the persisting pathogen and often associated with functional impairment of virus-specific T-cell responses. Costimulation through Glucocorticoid-induced TNFR-related protein (GITR) ca
Externí odkaz: https://doaj.org/article/979b21c3da294cbd905e53cf808fffb5
Zobrazit plný text záznamu
5
Peripheral and systemic antigens elicit an expandable pool of resident memory CD8 + T cells in the bone marrow
Autor: Nicholas Collins, Benjamin Nota, Edith Slot, Felix M. Behr, Laura K. Mackay, Monika C. Wolkers, Anna E. Oja, Mirjam H.M. Heemskerk, Sulima Geerman, Julia E. Prier, Pleun Hombrink, Regina Stark, Ramon Arens, Martijn A. Nolte, Klaas P. J. M. van Gisbergen, Maria Fernanda Pascutti, Eleni Panagioti, Giso Brasser, Sarah Hickson
Publikováno v: European Journal of Immunology, 49(6), 853-872. WILEY
European journal of immunology, 49(6), 853-872. Wiley-VCH Verlag
BM has been put forward as a major reservoir for memory CD8(+) T cells. In order to fulfill that function, BM should "store" memory CD8(+) T cells, which in biological terms would require these "stored" memory cells to be in disequilibrium with the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519da7d26fe970e543ef5173b819dd99
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063768380&origin=inward
Zobrazit plný text záznamu
6
GITR shapes humoral immunity by controlling the balance between follicular T helper cells and regulatory T follicular cells
Autor: Edith Slot, Giso Brasser, Martijn A. Nolte, Maria Fernanda Pascutti, René A. W. van Lier, Anna E. Oja
Publikováno v: Immunology letters, 222, 73-79. Elsevier
Follicular helper CD4+ T-cells (Tfh) control humoral immunity by driving affinity maturation and isotype-switching of activated B-cells. Tfh localize within B-cell follicles and, upon encounter with cognate antigen, drive B-cell selection in germinal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de19ca6304d42575d92f18751bf2db6d
https://pure.amc.nl/en/publications/gitr-shapes-humoral-immunity-by-controlling-the-balance-between-follicular-t-helper-cells-and-regulatory-t-follicular-cells(ad1a31d3-6ec2-4235-907c-69db8b769d6b).html
Zobrazit plný text záznamu
9
CXCR4, but not CXCR3, drives CD8(+) T-cell entry into and migration through the murine bone marrow
Autor: Graham Anderson, Mark Hoogenboezem, Edith Slot, Martijn A. Nolte, Marieke Goedhart, Stephanie Gessel, Carlijn Voermans, Jaap D. van Buul, Ellis Gielen, Sulima Geerman, Beth Lucas, Stephan Huveneers, Robbert van der Voort, Timo Rademakers, Harry Dolstra
Publikováno v: European Journal of Immunology, 49, 576-589
European Journal of Immunology, 49(4), 576-589. Wiley
European Journal of Immunology, 49, 4, pp. 576-589
European journal of immunology, 49(4), 576-589. Wiley-VCH Verlag
The BM serves as a blood-forming organ, but also supports the maintenance and immune surveillance function of many T cells. Yet, in contrast to other organs, little is known about the molecular mechanisms that drive T-cell migration to and localizati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c6c2ad0556ccb1bf9f7414c24b7fbf
http://hdl.handle.net/2066/202774
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje