Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Edita Aliwarga"'
Autor:
Ruth Jinfen Chai, Hendrikje Werner, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenneth Kian Boon Tan, Choong Tat Keng, Shi Ling Ng, Wei Leong Chew, Michael Ferenczi, Brian Burke, Roger Sik Yin Foo, Colin L. Stewart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are the second most common inherited cause of Dilated Cardiomyopathy, a major form of heart failure. Here the authors show that disruption of the nuclear protein SUN1 in cardiomyocytes, by AAV mediated transduction of a S
Externí odkaz:
https://doaj.org/article/c8e8b6f93e7b442686a2d1ede70d7399
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Objective Escherichia coli is a normal inhabitant of mammalian’s gut, but some strains acquired virulence factor and became pathogenic. Enterotoxigenic E. coli (ETEC), enterohemorrhagic E. coli (EHEC), enteropathogenic E. coli (EPEC), ente
Externí odkaz:
https://doaj.org/article/96a3bebe8a8b418d8b4980b697358be4
Autor:
Jennifer P. Newman, Grace Y. Wang, Kazuhiko Arima, Shou P. Guan, Michael R. Waters, Webster K. Cavenee, Edward Pan, Edita Aliwarga, Siao T. Chong, Catherine Y. L. Kok, Berwini B. Endaya, Amyn A. Habib, Tomohisa Horibe, Wai H. Ng, Ivy A. W. Ho, Kam M. Hui, Tomasz Kordula, Paula Y. P. Lam
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Interleukin-13 receptor alpha 2 is highly expressed in glioblastoma multiforme but its role in this malignancy is unclear. Here the authors show that this receptor interacts with mutant EGFR, stimulating its kinase activity, thus inducing proliferati
Externí odkaz:
https://doaj.org/article/86a25a0c882247c39b38bbcac00ca539
Autor:
Nirmala Arul Rayan, Vibhor Kumar, Jonathan Aow, Naghmeh Rastegar, Michelle Gek Liang Lim, Nicholas O’Toole, Edita Aliwarga, Danusa Mar Arcego, Hui Ting Grace Yeo, Jen Yi Wong, May Yin Lee, Florian Schmidt, Hajira Shreen Haja, Wai Leong Tam, Tie-Yuan Zhang, Josie Diorio, Christoph Anacker, Rene Hen, Carine Parent, Michael J Meaney, Shyam Prabhakar
Publikováno v:
Molecular Psychiatry. 27:4510-4525
Depression and anxiety are major global health burdens. Although SSRIs targeting the serotonergic system are prescribed over 200 million times annually, they have variable therapeutic efficacy and side effects, and mechanisms of action remain incompl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc06ddc305fbbd950921fb8126b2e3c
https://doi.org/10.1038/s41380-022-01725-1
https://doi.org/10.1038/s41380-022-01725-1
Autor:
Alexandre Chojnowski, Colin L. Stewart, Lois Yu En Sim, Yin Loon Lee, Choong Tat Keng, Matias Ilmari Autio, Tuan Danh Anh Luu, Ying Jie Loh, Khaing Thet Nyein, Roger Foo, Michael A. Ferenczi, Brian Burke, Shi Ling Ng, Kenneth Kian Boon Tan, Bhavya Sharma, Irina Solovei, Yu Haiyang, Jason Wen Long Cheong, Ruth Jinfen Chai, Peter Yiqing Li, Edita Aliwarga, Raju Navasankari, Martina Maric, Hendrikje Werner, Wei Leong Chew
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are a common cause of monogenic dilated cardiomyopathy. Here we show that mice with a cardiomyocyte-specific Lmna deletion develop cardiac failure and die within 3–4 weeks after inducing the mutation. When the same Lmna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afa6944b68830856ba3cb421879425b
http://europepmc.org/articles/PMC8342462
http://europepmc.org/articles/PMC8342462
Autor:
Ivy A.W. Ho, Berwini Endaya, Catherine Y. L. Kok, Siao T. Chong, Paula Y.P. Lam, Kazuhiko Arima, Jennifer P. Newman, Kam M. Hui, Michael R. Waters, Edita Aliwarga, Edward Pan, Webster K. Cavenee, Tomohisa Horibe, Amyn A. Habib, Tomasz Kordula, Shou P. Guan, Grace Y. Wang, Wai Hoe Ng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications
The interleukin-13 receptor alpha2 (IL-13Rα2) is a cancer-associated receptor overexpressed in human glioblastoma multiforme (GBM). This receptor is undetectable in normal brain which makes it a highly suitable target for diagnostic and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f22e40e95136394f76a30a46c06eb
https://doaj.org/article/86a25a0c882247c39b38bbcac00ca539
https://doaj.org/article/86a25a0c882247c39b38bbcac00ca539
Autor:
Edita Aliwarga, Yiqing Peter Li, Shi Ling Ng, Tingsen Benson Lim, Tuan Danh Anh Luu, Matthew Ackers-Johnson, Stephanie Sian, Lavenniah Annadoray, Roger Foo
Publikováno v:
Cardiovascular research. 115(14)
AimsWe and others have previously described the expression landscape of circular RNA (circRNA) in mouse and human hearts. However, the functional relevance of many of these abundantly expressed cardiomyocyte circRNA remains to be fully explored. Amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ea14a6b02342f9fabde28d78752736
https://pubmed.ncbi.nlm.nih.gov/31147691
https://pubmed.ncbi.nlm.nih.gov/31147691
Autor:
Degang Wu, Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, Nicolas Bertin, Clarabelle Bitong Lin, Chiea Chuen Khor, Michael DeGiorgio, Shanshan Cheng, Li Bao, Neerja Karnani, William Ying Khee Hwang, Sonia Davila, Patrick Tan, Asim Shabbir, Angela Moh, Eng-King Tan, Jia Nee Foo, Liuh Ling Goh, Khai Pang Leong, Roger S.Y. Foo, Carolyn Su Ping Lam, Arthur Mark Richards, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Huck Hui Ng, Jianjun Liu, Chaolong Wang, Matthew Andrew Ackers-Johnson, Edita Aliwarga, Kenneth Hon Kim Ban, Denis Bertrand, John C. Chambers, Dana Leng Hui Chan, Cheryl Xue Li Chan, Miao Li Chee, Miao Ling Chee, Pauline Chen, Yunxin Chen, Elaine Guo Yan Chew, Wen Jie Chew, Lynn Hui Yun Chiam, Jenny Pek Ching Chong, Ivan Chua, Stuart A. Cook, Wei Dai, Rajkumar Dorajoo, Chuan-Sheng Foo, Rick Siow Mong Goh, Axel M. Hillmer, Ishak D. Irwan, Fazlur Jaufeerally, Asif Javed, Justin Jeyakani, John Tat Hung Koh, Jia Yu Koh, Pavitra Krishnaswamy, Jyn Ling Kuan, Neelam Kumari, Ai Shan Lee, Seow Eng Lee, Sheldon Lee, Yen Ling Lee, See Ting Leong, Zheng Li, Peter Yiqing Li, Jun Xian Liew, Oi Wah Liew, Su Chi Lim, Weng Khong Lim, Chia Wei Lim, Tingsen Benson Lim, Choon Kiat Lim, Seet Yoong Loh, Au Wing Lok, Calvin W.L. Chin, Shivani Majithia, Sebastian Maurer-Stroh, Wee Yang Meah, Shi Qi Mok, Niranjan Nargarajan, Pauline Ng, Sarah B. Ng, Zhenyuan Ng, Jessica Yan Xia Ng, Ebonne Ng, Shi Ling Ng, Simon Nusinovici, Chin Thing Ong, Bangfen Pan, Vincent Pedergnana, Stanley Poh, Shyam Prabhakar, Kumar M. Prakash, Ivy Quek, Charumathi Sabanayagam, Wei Qiang See, Yee Yen Sia, Xueling Sim, Wey Cheng Sim, Jimmy So, Dinna K.N. Soon, E. Shyong Tai, Nicholas Y. Tan, Louis C.S. Tan, Hong Chang Tan, Wilson Lek Wen Tan, Moses Tandiono, Amanda Tay, Sahil Thakur, Yih Chung Tham, Zenia Tiang, Grace Li-Xian Toh, Pi Kuang Tsai, Lavanya Veeravalli, Chandra S. Verma, Ling Wang, Min Rui Wang, Wing-Cheong Wong, Zhicheng Xie, Khung Keong Yeo, Liang Zhang, Weiwei Zhai, Yi Zhao
Publikováno v:
Cell, 179(3), 736-749.e15. CELL PRESS
Underrepresentation of Asian genomes has hindered population and medical genetics research on Asians, leading to population disparities in precision medicine. By whole-genome sequencing of 4,810 Singapore Chinese, Malays, and Indians, we found 98.3 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fc6f1f77725c9278d94850e16244b8
https://hdl.handle.net/11370/91129d3f-e884-4e42-a172-38209156be75
https://hdl.handle.net/11370/91129d3f-e884-4e42-a172-38209156be75