Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Edit Schnitzer"'
Publikováno v:
European Biophysics Journal. 36:499-515
Free radicals, formed via different mechanisms, induce peroxidation of membrane lipids. This process is of great importance because it modifies the physical properties of the membranes, including its permeability to different solutes and the packing
Publikováno v:
Chemistry and Physics of Lipids. 135:69-82
Most of the studies on the solubilization of model membranes by Triton X-100 (TR) involve one lipid. The aim of the present study was to evaluate the effect of the addition of cholesterol on the solubilization of bilayers made of palmitoyloleoylphosp
Publikováno v:
Chemistry and Physics of Lipids. 126:55-76
Most of the studies on the solubilization of model membranes conducted thus far involved model membranes made of liquid-crystalline phospholipids. Relatively little is known on the influence of temperature and of the phase of the lipid bilayers on th
Publikováno v:
Free Radical Biology and Medicine. 29:131-146
Comparison of the kinetic profiles of copper-induced peroxidation of HDL and LDL at different copper concentrations reveals that under all the studied experimental conditions HDL is more susceptible to oxidation than LDL. The mechanism responsible fo
Autor:
Miron Krimsky, Edit Schnitzer, Hadassa Shinar, Arie Dagan, Ilya Pinchuk, Saul Yedgar, Dov Lichtenberg
Publikováno v:
Chemistry and Physics of Lipids. 104:149-160
The amphiphilic polysaccharide hyaluronic acid-linked phosphatidylethanolamine (HyPE), synthesized by covalently binding dipalmitoyl-phosphatidylethanolamine (DPPE) to short chain hyaluronic acid (mol. wt. approximately = 30 000), interacts with low-
Publikováno v:
Free Radical Research. 23:137-149
Copper-induced LDL oxidation is characterized by an 'induction phase' (lag phase) during which the endogenous antioxidants are consumed, followed by a 'propagation phase' in which the LDL-associated polyunsaturated fatty acids are oxidized. Oxidation
Publikováno v:
Chemistry and physics of lipids. 164(1)
Evaluation of the activity of antioxidants is commonly based on measurements of the effect of a specific antioxidant on redox reactions conducted in a solution. Given the difference between reactions that occur in homogeneous solutions and those that
Publikováno v:
Chemistry and physics of lipids. 146(1)
Lipid peroxidation is believed to play an important role in the pathogenesis of many diseases. Much research has therefore been devoted to peroxidation of different lipids in biomembranes and in model systems (liposomes) of different compositions. Ye
Publikováno v:
Free radical research. 38(11)
Oxidative modifications of LDL are involved in atherogenesis. Previously we have developed a simple assay to evaluate the susceptibility of lipids to copper-induced peroxidation in the relatively natural milieu of unfractionated serum in the presence
Publikováno v:
Biochimica et biophysica acta. 1488(1-2)
The hydrolysis of cell membrane phospholipids by phospholipase A(2) (PLA(2)) leads to the production of numerous lipid mediators of diverse pathological conditions, mainly inflammatory diseases. These include lysophospholipids and their derivatives,