Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Edison T. Liu"'
Autor:
Eric C. Anderson, John DiPalazzo, F. Lee Lucas, Michael J. Hall, Andrey Antov, Petra Helbig, Jennifer Bourne, Leah Graham, Lory Gaitor, Christine Lu-Emerson, Leslie S. Bradford, Roger Inhorn, Sarah J. Sinclair, Philip L. Brooks, Christian A. Thomas, Karen Rasmussen, Paul K. J. Han, Edison T. Liu, Jens Rueter
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Genomic tumor testing (GTT) is an emerging technology aimed at identifying variants in tumors that can be targeted with genomically matched drugs. Due to limited resources, rural patients receiving care in community oncology settings may be
Externí odkaz:
https://doaj.org/article/dcdaf957786f4e43911da55a8d4b389f
Autor:
Patience Mukashyaka, Pooja Kumar, David J. Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T. Courtois, Olga Anczukow, Edison T. Liu, Jeffrey H. Chuang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Three-dimensional (3D) organoid cultures are flexible systems to interrogate cellular growth, morphology, multicellular spatial architecture, and cellular interactions in response to treatment. However, computational methods for analysis of
Externí odkaz:
https://doaj.org/article/2cd01544c4564c99a84c08267edfbe10
Autor:
Francesca Menghi, Edison T. Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Cancer functional genomics is the study of how genetic, epigenetic, and transcriptional alterations affect cancer phenotypes, such as growth and therapeutic response. Here, we comment on how, taking advantage of next generation sequencing, functional
Externí odkaz:
https://doaj.org/article/8d4a521f864144f8ab586f13a9c1c017
Autor:
Karen L. Svenson, Stephen D. Krasinski, Michael Ellis, Nadia Rosenthal, Edison T. Liu, Kenneth H. Fasman
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 10 (2022)
Externí odkaz:
https://doaj.org/article/af83b92c2a734ff886296c5d4cdc230d
Autor:
Ping Wang, Zhonghui Tang, Byoungkoo Lee, Jacqueline Jufen Zhu, Liuyang Cai, Przemyslaw Szalaj, Simon Zhongyuan Tian, Meizhen Zheng, Dariusz Plewczynski, Xiaoan Ruan, Edison T. Liu, Chia-Lin Wei, Yijun Ruan
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Acute promyeloid leukemia (APL) is characterized by the oncogenic fusion protein PML-RARα, a major etiological agent in APL. However, the molecular mechanisms underlying the role of PML-RARα in leukemogenesis remain largely unkn
Externí odkaz:
https://doaj.org/article/ca1f2e55568d425387ee866b9625748d
Autor:
Kunal Sanghavi, W. Gregory Feero, Debra J. H. Mathews, Anya E. R. Prince, Lori Lyn Price, Edison T. Liu, Kyle B. Brothers, J. Scott Roberts, Charles Lee
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Employers have begun to offer voluntary workplace genomic testing (wGT) as part of employee wellness benefit programs, but few empirical studies have examined the ethical, legal, and social implications (ELSI) of wGT. To better understand employee pe
Externí odkaz:
https://doaj.org/article/8d3e69c122b04843b243be4ae40273f1
Autor:
Yi Fang Lee, Lance David Miller, Xiu Bin Chan, Michael A. Black, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Edison T. Liu, Kartiki V. Desai
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/abf0700fcb054e95b107c5635b33a943
Autor:
Nagarajan Kannan, Jian Kang, Xiangjun Kong, Jianzhong Tang, Jo K. Perry, Kumarasamypet M. Mohankumar, Lance D. Miller, Edison T. Liu, Hichem C. Mertani, Tao Zhu, Prudence M. Grandison, Dong-Xu Liu, Peter E. Lobie
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 12, Pp 1041-1053 (2010)
We report herein that trefoil factor 3 (TFF3) is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma. Forced expression of TFF3 in mammary carcinoma cells increased cell proliferation and survival, enhanced anchorage-independen
Externí odkaz:
https://doaj.org/article/5f410d894ad849ababfc5ad98bc8d650
Publikováno v:
BioTechniques, Vol 34, Iss 6, Pp 1264-1270 (2003)
DNA microarrays are valuable but expensive tools for expression profiling of cells, tissues, and organs. The design of custom microarrays leads to cost reduction without necessarily compromising their biological value. Here we present a strategy for
Externí odkaz:
https://doaj.org/article/7fc63eaa24444c078ed386bb0d90f34f
Autor:
Xing Yi Woo, Anuj Srivastava, Philip C. Mack, Joel H. Graber, Brian J. Sanderson, Michael W. Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A. Tsai, James Keck, Mingshan Cheng, Margaret Bundy, Emily L. Jocoy, Jonathan W. Riess, William Holland, Stephen C. Grubb, James G. Peterson, Grace A. Stafford, Carolyn Paisie, Steven B. Neuhauser, R. Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G. Tepper, Neal Goodwin, Susan D. Airhart, Primo N. Lara, Thomas H. Openshaw, Edison T. Liu, David R. Gandara, Carol J. Bult
Publikováno v:
Cancer Res
Cancer research, vol 82, iss 22
Cancer research, vol 82, iss 22
Patient-derived xenograft (PDX) models are an effective preclinical in vivo platform for testing the efficacy of novel drugs and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung