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Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 30:528-530
Chlorpropamide, given intravenously (4 mg/kg) to 7 water-loaded patients with vasopressin-responsive diabetes insipidus, significantly reduced the urinary flow, free-water clearance and osmolal clearance; the creatinine clearance, urinary sodium excr
Publikováno v:
The American journal of the medical sciences. 273(2)
The antidiuretic action of chlorpropamide was studied in 10 diabetes insipidus patients sensitive to vasopressin and 15 normal subjects. After an oral load of water followed by sustained hydration through water ingestion in a volume equivalent to the