Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Edison H Osorio"'
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0215793 (2019)
Cyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule t
Externí odkaz:
https://doaj.org/article/a386f1c5b36647d59c30a274387fd500
Autor:
Luciana R. Tallini, Karen Acosta León, Raúl Chamorro, Edison H. Osorio, Jaume Bastida, Lou Jost, Nora H. Oleas
Publikováno v:
Life, Vol 14, Iss 8, p 924 (2024)
Ecuador is an important center of biodiversity for the plant subfamily Amaryllidoideae, known for its important bioactive molecules. This study aimed to assess the chemical and biological potential of four different Amaryllidoideae species collected
Externí odkaz:
https://doaj.org/article/aebc0124e4b64301baaf4fa573603e28
Autor:
Luis F. Salas-Nuñez, Alvaro Barrera-Ocampo, Paola A. Caicedo, Natalie Cortes, Edison H. Osorio, Maria F. Villegas-Torres, Andres F. González Barrios
Publikováno v:
Metabolites, Vol 14, Iss 3, p 154 (2024)
Enzyme–substrate interactions play a fundamental role in elucidating synthesis pathways and synthetic biology, as they allow for the understanding of important aspects of a reaction. Establishing the interaction experimentally is a slow and costly
Externí odkaz:
https://doaj.org/article/9d91e700c17642a79708279f54bfd68c
Autor:
Lina Trujillo, Janeth Bedoya, Natalie Cortés, Edison H. Osorio, Juan-Carlos Gallego, Hawer Leiva, Dagoberto Castro, Edison Osorio
Publikováno v:
Molecules; Volume 28; Issue 6; Pages: 2601
Cancer is a major cause of death and an impediment to increasing life expectancy worldwide. With the aim of finding new molecules for chemotherapeutic treatment of epidemiological relevance, ten alkaloid fractions from Amaryllidaceae species were tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f55ec8bce45d57fba736e81ea2be7bf
Autor:
Luciana R. Tallini, Edison H. Osorio, Strahil Berkov, Laura Torras-Claveria, María L. Rodríguez-Escobar, Francesc Viladomat, Alan W. Meerow, Jaume Bastida
Publikováno v:
Plants; Volume 11; Issue 24; Pages: 3549
Plant biodiversity is an important source of compounds with medicinal properties. The alkaloid galanthamine, first isolated from Galanthus woronowii (Amaryllidaceae), is approved by the FDA for the palliative treatment of mild to moderate Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f11a8be84f585d849a910982cb61de
Autor:
Raúl Moreno, Luciana R. Tallini, Cristina Salazar, Edison H. Osorio, Evelin Montero, Jaume Bastida, Nora H. Oleas, Karen Acosta León
Publikováno v:
Molecules, Vol 25, Iss 9, p 2092 (2020)
It is estimated that 50 million people in the world live with dementia, 60–70% of whom suffer from Alzheimer’s disease (AD). Different factors are involved in the development of AD, including a reduction in the cholinergic neurotransmission level
Externí odkaz:
https://doaj.org/article/fd05e83a2e644a238e09718d18efc83c
Autor:
Luciana R. Tallini, Jaume Bastida, Natalie Cortes, Edison H. Osorio, Cristina Theoduloz, Guillermo Schmeda-Hirschmann
Publikováno v:
Molecules, Vol 23, Iss 7, p 1532 (2018)
Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for the clinical treatment of Alzheimer’s disease. The chemistry and bioactivity of Chilean representatives of Rhodophiala genus from the family of Amaryllidaceae
Externí odkaz:
https://doaj.org/article/1ba81242e24a43fe8616df880d390db6
Autor:
Luciana R. Tallini, Edison H. Osorio, Vanessa Dias dos Santos, Warley de Souza Borges, Marcel Kaiser, Francesc Viladomat, José Angelo S. Zuanazzi, Jaume Bastida
Publikováno v:
Molecules, Vol 22, Iss 12, p 2191 (2017)
The Amaryllidaceae family has proven to be a rich source of active compounds, which are characterized by unique skeleton arrangements and a broad spectrum of biological activities. The aim of this work was to perform the first detailed study of the a
Externí odkaz:
https://doaj.org/article/4edfad03decc4f169f2f354fd780530b
Autor:
Karina Sierra, Jean Paulo de Andrade, Luciana R. Tallini, Edison H. Osorio, Osvaldo Yañéz, Manuel Isaías Osorio, Nora H. Oleas, Olimpo García-Beltrán, Warley de S. Borges, Jaume Bastida, Edison Osorio, Natalie Cortes
Publikováno v:
Biomedicine & Pharmacotherapy. 150:113016
Zephyranthes carinata Herb., a specie of the Amaryllidoideae subfamily, has been reported to have inhibitory activity against acetylcholinesterase. However, scientific evidence related to their bioactive alkaloids has been lacking. Thus, this study d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2585257166644afebf42c8776ef5bd9
https://doi.org/10.1016/j.biopha.2022.113016
https://doi.org/10.1016/j.biopha.2022.113016
Publikováno v:
Phytochemical analysis : PCA. 29(2)
Enzymatic inhibition of acetylcholinesterase (AChE) is an essential therapeutic target for the treatment of Alzheimer's disease (AD) and AChE inhibitors are the first-line drugs for it treatment. However, butyrylcholinesterase (BChE), contributes cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::977a88d6bcd97c6691023e08570796c2
https://pubmed.ncbi.nlm.nih.gov/29044771
https://pubmed.ncbi.nlm.nih.gov/29044771