Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Edina Csaszar"'
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34511 (2012)
Avastin® (bevacizumab) is a protein drug widely used for cancer treatment although its further use is questionable due to serious side effects reported. As no systematic proteomic study on posttranslational modifications (PTMs) was reported so far,
Externí odkaz:
https://doaj.org/article/9856473a8af342a69c4c0b6cc2f6c8f6
Publikováno v:
Behavioural Brain Research. 264:126-134
Protein phosphorylation is a well-known and well-documented mechanism in memory processes. Although a large series of protein kinases involved in memory processes have been reported, information on phosphoproteins is limited. It was therefore the aim
Autor:
Bernhard Wurzinger, Markus Teige, Edina Csaszar, Barbara Pfister, Roman G. Bayer, Daniela Hofmann-Rodrigues, Norbert Mehlmer, Simon Stael
Publikováno v:
The Plant Journal. 63:484-498
Plants use different signalling pathways to respond to external stimuli. Intracellular signalling via calcium-dependent protein kinases (CDPKs) or mitogen-activated protein kinases (MAPKs) present two major pathways that are widely used to react to a
Autor:
Edina Csaszar, Verena Jantsch, Pawel Pasierbek, Alexandra Penkner, Alexander Woglar, Alexandra Fridkin, Thomas Machacek, Yosef Gruenbaum, Gustav Ammerer, Antoine Baudrimont, Jiradet Gloggnitzer
Publikováno v:
Cell. 139:920-933
Summary Genome haploidization during meiosis depends on recognition and association of parental homologous chromosomes. The C. elegans SUN/KASH domain proteins Matefin/SUN-1 and ZYG-12 have a conserved role in this process. They bridge the nuclear en
Autor:
Ramsay J. McFarlane, Edina Csaszar, Josef Loidl, Felicity Z. Watts, Mário Špírek, Anna Estreicher, Jennifer L. Wells
Publikováno v:
Chromosoma. 119:59-72
In the fission yeast, Schizosaccharomyces pombe, synaptonemal complexes (SCs) are not formed during meiotic prophase. However, structures resembling the axial elements of SCs, the so-called linear elements (LinEs) appear. By in situ immunostaining, w
Autor:
Marion Pavlic, Harald Köfeler, Edina Csaszar, Rainer Schuhmacher, Kathrin Libiseller, Birthe Schubert, Herbert Oberacher, Michael Sulyok
Publikováno v:
Journal of Mass Spectrometry. 44:485-493
The inter-instrument and inter-laboratory transferability of a tandem mass spectral reference library originally built on a quadrupole-quadrupole-time-of-flight instrument was examined. The library consisted of 3759 MS/MS spectra collected from 402 r
Autor:
Harald Köfeler, Edina Csaszar, Kathrin Libiseller, Michael Sulyok, Marion Pavlic, Birthe Schubert, Rainer Schuhmacher, Herbert Oberacher
Publikováno v:
Journal of Mass Spectrometry. 44:494-502
A sophisticated matching algorithm developed for highly efficient identity search within tandem mass spectral libraries is presented. For the optimization of the search procedure a collection of 410 tandem mass spectra corresponding to 22 compounds w
Autor:
Andreas Verhounig, Edina Csaszar, Celine Forzani, David Lecourieux, Sergio de la Fuente van Bentem, Andrea Barta, Jos Joore, Zdravko J. Lorković, Heribert Hirt, Ilse Dohnal, Elisabeth Roitinger, Dorothea Anrather, Joshua Buijnink, Claudia Jonak, Alessandro Carreri
Publikováno v:
Journal of Proteome Research. 7:2458-2470
An estimated one-third of all proteins in higher eukaryotes are regulated by phosphorylation by protein kinases (PKs). Although plant genomes encode more than 1000 PKs, the substrates of only a small fraction of these kinases are known. By mass spect
Publikováno v:
PROTEOMICS. 6:775-784
Recombinant human growth hormone (rhGH) is used for the treatment of several disorders. Structural integrity of rhGH is of critical importance for its clinical use and modifications thereof may act as markers in situations such as rhGH doping, as ill
Autor:
Dorothea Anrather, Elisabeth Roitinger, Edina Csaszar, Heribert Hirt, Sergio de la Fuente van Bentem
Publikováno v:
Physiologia Plantarum. 126:110-119
Reversible phosphorylation of proteins plays a key role in many regulatory processes that lie at the basis of life. With plants, much research has focused on protein kinases that are involved in the adaptation to different stress conditions, such as