StreptInCor: a candidate vaccine epitope against S. pyogenes infections induces protection in outbred mice.

Autor: Edilberto Postol, Raquel Alencar, Fabio T Higa, Samar Freschi de Barros, Lea M F Demarchi, Jorge Kalil, Luiza Guilherme

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60969 (2013)

Infection with Streptococcus pyogenes (S. pyogenes) can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence factor, and certain regions of its N-terminus can trigger autoimmune sequelae such as rheumatic

Externí odkaz: https://doaj.org/article/0235416479ea4224bc8102df7085ffaf

Group A streptococcus adsorbed vaccine: repeated intramuscular dose toxicity test in minipigs

Autor: Luiz Carlos de Sá-Rocha, Jorge Kalil, Luiza Guilherme, Léa Maria Macruz Ferreira Demarchi, Roney Orismar Sampaio, R. Alencar, Maria Cristina Donadio Abduch, Edilberto Postol

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

Streptococcus pyogenes infection continues to be a worldwide public health problem causing various diseases in humans and plays an important role in the pathogenesis of rheumatic fever and rheumatic heart disease. We developed a vaccine candidate to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a817b91cce7c3b92eb44432cdecd6158

Analysis of the coverage capacity of the StreptInCor candidate vaccine against Streptococcus pyogenes

Autor: Jorge Kalil, Edilberto Postol, R. Alencar, Luiza Guilherme, Samar Freschi de Barros, Karine De Amicis, Helen Andrade Arcuri, Cibelly Goulart, Carlo de Oliveira Martins

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Streptococcus pyogenes is responsible for infections as pharyngitis, sepsis, necrotizing fasciitis and streptococcal toxic shock syndrome. The M protein is the major bacterial antigen and consists of both polymorphic N-terminal portion and a conserve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ebedaa0169dc25a95e403f9306491c
https://doi.org/10.1016/j.vaccine.2013.08.043

A Vaccine against Streptococcus pyogenes

Autor: Jorge Kalil, Karen Francine Köhler, Frederico Moraes Ferreira, Luiza Guilherme, Edilberto Postol

Publikováno v: American Journal of Cardiovascular Drugs. 13:1-4

Streptococcus pyogenes causes severe, invasive infections such as the sequelae associated with acute rheumatic fever, rheumatic heart disease, acute glomerulonephritis, uncomplicated pharyngitis, and pyoderma. Efforts to produce a vaccine against S.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf83df5f1f43785fa7db75053f7f33e
https://doi.org/10.1007/s40256-013-0005-8

A vaccine against S. pyogenes: Design and experimental immune response

Autor: Oliver Pérez, S. Freschi de Barros, Caridad Zayas, William Ribeiro da Silva, Jorge Kalil, R. Alencar, Edilberto Postol, C. R. Puschel, Miriam Lastre, Luiza Guilherme, F. Higa, Vanessa de Moura Sá-Rocha, Luiz Carlos de Sá-Rocha

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Streptococcus pyogenes causes severe invasive infections: the post-streptococcal sequelae of acute rheumatic fever (RF) and rheumatic heart disease (RHD), acute glomerulonephritis, and uncomplicated pharyngitis and pyoderma. Efforts to produce a vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f49f6f14022e4480d74cee4ad5a230
https://doi.org/10.1016/j.ymeth.2009.03.024