Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edikarlos Brasil"'
Publikováno v:
Marine Drugs, Vol 18, Iss 4, p 203 (2020)
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives o
Externí odkaz:
https://doaj.org/article/da1c150da84245ef959e1d162ca5c07f
Autor:
Sikabwe Noki, Edikarlos Brasil, Haixiang Zhang, Thomas Bruckdorfer, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Peptides of importance to both academia and industry are mostly synthesized in the solid-phase mode using a two-dimensional scheme. The so-called Fmoc/tBu strategy, where the groups are removed by piperidine and TFA, respectively, is currently the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914f641519456fe76c039550715a6241
https://doi.org/10.1021/acs.joc.2c01056
https://doi.org/10.1021/acs.joc.2c01056
Autor:
Paul V. Bernhardt, Rosivaldo S. Borges, José Rogério A. Silva, Jerônimo Lameira, Thiago de Melo e Silva, Craig M. Williams, Edikarlos Brasil, Luciana Morais Canavieira, Cláudio Nahum Alves
Publikováno v:
Molecular Simulation. 47:762-770
Tyrosinase (TYR) is a key enzyme that catalyzes the synthesis of melanin in plants, microorganisms and mammalian cells. Kojic acid (KA) is a well-known TYR inhibitor widely used as a popular cosmetic skin-lightening ingredient. However, KA is reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fdbf0218a9182669e4845034bf8ef02
https://doi.org/10.1080/08927022.2021.1926455
https://doi.org/10.1080/08927022.2021.1926455
Autor:
Praveen K. Chinthakindi, Kamal K. Rajbongshi, Thavendran Govender, Maya M. Makatini, Ekemini D. Akpan, Mzilikazi F. Khumalo, Hendrik G. Kruger, Edikarlos Brasil, Per I. Arvidsson, Tricia Naicker
Publikováno v:
RSC Advances. 8:37503-37507
Herein, we report the preparation of 1,2,4-thiadiazinane 1,1-dioxides from reaction of β-aminoethane sulfonamides with dichloromethane, dibromomethane and formaldehyde as methylene donors. The β-aminoethane sulfonamides were obtained through sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2254533c3722ab3bfc610a5b5b0b84b5
https://doi.org/10.1039/c8ra07627h
https://doi.org/10.1039/c8ra07627h
Publikováno v:
Zeitschrift für Kristallographie - New Crystal Structures. 234:169-171
C23.5H23FN2O2S, Mr = 416.50, monoclinic, C2/c (no. 15), a = 27.2594(19) Å, b = 5.7351(4) Å, c = 26.1139(18) Å, β = 102.009(2)°, V = 3993.2(5) Å3, Z = 8, R gt(F) = 0.0358, wR ref(F 2) = 0.0958 T = 100(2) K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e6190e5bb1cac3cedbe1251827e4eb
https://doi.org/10.1515/ncrs-2018-0253
https://doi.org/10.1515/ncrs-2018-0253
Publikováno v:
Zeitschrift für Kristallographie-New Crystal Structures, Vol 234, Iss 3, Pp 441-442 (2019)
C9H6FNO2S, triclinic, P1̄ (no. 2), a = 7.2786(2) Å, b = 8.1014(3) Å, c = 16.1084(5) Å, α = 76.320(1)°, β = 87.918(1)°, γ = 80.784(1)°, V = 911.00(5) Å3, Z = 4, R gt(F) = 0.0298, wR ref(F 2) = 0.0857, T = 100(2) K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8453c3dc694b51a5f94cd794c78543
https://doi.org/10.1515/ncrs-2018-0449
https://doi.org/10.1515/ncrs-2018-0449
Autor:
Edikarlos Brasil, José Rogério A. Silva, José Luiz Martins do Nascimento, Cláudio Nahum Alves, Barbarella de Matos Macchi, Paul V. Bernhardt, Erica de Tássia Carvalho Cardoso, Craig M. Williams, Luciana Morais Canavieira, Vera Lucia Eifler-Lima, Edilene O. Silva, Dharmarajan Sriram, Jerônimo Lameira
Publikováno v:
Chemical biologydrug design. 90(5)
Inhibition of mushroom tyrosinase was observed with synthetic dihydropyrano[3,2-b]chromenediones. Among them, DHPC04 displayed the most potent tyrosinase inhibitory activity with a Ki value of 4μM, comparable to the reference standard inhibitor koji
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc99ef6cb776f991bef68a1a8aeca79a
https://pubmed.ncbi.nlm.nih.gov/28390091
https://pubmed.ncbi.nlm.nih.gov/28390091