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Akademický článek

The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics

Autor: Mariame S. Kane, Gloria A. Benavides, Edie Osuma, Michelle S. Johnson, Helen E. Collins, Yecheng He, David Westbrook, Silvio H. Litovsky, Kasturi Mitra, John C. Chatham, Victor Darley-Usmar, Martin E. Young, Jianhua Zhang

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)

Abstract Mitochondria morphology and function, and their quality control by mitophagy, are essential for heart function. We investigated whether these are influenced by time of the day (TOD), sex, and fed or fasting status, using transmission electro

Externí odkaz: https://doaj.org/article/404d2c5db08241938901383fabf3f138

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Akademický článek

Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration

Autor: Van N. Huynh, Gloria A. Benavides, Michelle S. Johnson, Xiaosen Ouyang, Balu K. Chacko, Edie Osuma, Toni Mueller, John Chatham, Victor M. Darley-Usmar, Jianhua Zhang

Publikováno v: Molecular Brain, Vol 15, Iss 1, Pp 1-16 (2022)

Abstract The accumulation of neurotoxic proteins characteristic of age-related neurodegenerative pathologies such as Alzheimer’s and Parkinson’s diseases is associated with the perturbation of metabolism, bioenergetics, and mitochondrial quality

Externí odkaz: https://doaj.org/article/68b3c3eb510e4385addb8c4b50678f84

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