Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Edi Simoni"'
Autor:
Elisa Callegari, Paola Guerriero, Cristian Bassi, Lucilla D’Abundo, Antonio Frassoldati, Edi Simoni, Laura Astolfi, Enrico Maria Silini, Silvia Sabbioni, Massimo Negrini
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 538-549 (2022)
Palbociclib is in early-stage clinical testing in advanced hepatocellular carcinoma (HCC). Here, we investigated whether the anti-tumor activity of palbociclib, which prevents the CDK4/6-mediated phosphorylation of RB1 but simultaneously activates AK
Externí odkaz:
https://doaj.org/article/701879adeaa542da8665c540f3d200b5
Autor:
Emanuele Bernardinelli, Sebastian Roesch, Edi Simoni, Angela Marino, Gerd Rasp, Laura Astolfi, Antonio Sarikas, Silvia Dossena
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Hearing loss (HL) is the most common sensory defect and affects 450 million people worldwide in a disabling form. Pathogenic sequence alterations in the POU3F4 gene, which encodes a transcription factor, are causative of the most common type of X-lin
Externí odkaz:
https://doaj.org/article/b0ce63a6409749afb9a0d8221bd06859
Autor:
Diego Cazzador, Laura Astolfi, Antonio Daloiso, Giulia Tealdo, Edi Simoni, Antonio Mazzoni, Elisabetta Zanoletti, Gino Marioni
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6522 (2023)
Although diagnosis and treatment of vestibular schwannomas (VSs) improved in recent years, no factors have yet been identified as being capable of predicting tumor growth. Molecular rearrangements occur in neoplasms before any macroscopic morphologic
Externí odkaz:
https://doaj.org/article/2e82839e129a4b57900c5cc52f891236
Autor:
Giovanna Albertin, Laura Astolfi, Caterina Fede, Edi Simoni, Martina Contran, Lucia Petrelli, Cesare Tiengo, Diego Guidolin, Raffaele De Caro, Carla Stecco
Publikováno v:
Life, Vol 13, Iss 3, p 836 (2023)
Recently, the superficial fascia has been recognized as a specific anatomical structure between the two adipose layers—the superficial adipose tissue (SAT) and the deep adipose tissue (DAT). The evaluation of specific characteristics of cells, fibe
Externí odkaz:
https://doaj.org/article/cd0b02a1b3434294b6b8a58deb566a3c
Autor:
Filippo Valente, Edi Simoni, Erica Gentilin, Alessandro Martini, Elisabetta Zanoletti, Gino Marioni, Piero Nicolai, Laura Astolfi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14881 (2022)
The conjugation of drugs with nanoparticles represents an innovative approach for controlled and targeted administration of therapeutic agents. Nanoparticle-based systems have been tested for the inner ear therapy, increasing the drug diffusion and b
Externí odkaz:
https://doaj.org/article/c0442592ba074154886aa89b51e15920
Autor:
Mariarita Candito, Edi Simoni, Erica Gentilin, Alessandro Martini, Gino Marioni, Serena Danti, Laura Astolfi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1761 (2022)
The biocompatibility and the antioxidant activity of barium titanate (BaTiO3) and lithium niobate (LiNbO3) were investigated on a neuronal cell line, the PC12, to explore the possibility of using piezoelectric nanoparticles in the treatment of inner
Externí odkaz:
https://doaj.org/article/03a20a40872d441a86970dc3c25fad4e
Autor:
Edi Simoni, Erica Gentilin, Mariarita Candito, Giulia Borile, Filippo Romanato, Milvia Chicca, Sara Nordio, Marta Aspidistria, Alessandro Martini, Diego Cazzador, Laura Astolfi
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
A cochlear implant (CI) is an electronic device that enables hearing recovery in patients with severe to profound hearing loss. Although CIs are a successful treatment for profound hearing impairment, their effectivity may be improved by reducing dam
Externí odkaz:
https://doaj.org/article/dbcaebaa45b24c839fb8352b291a99fb
Autor:
Laura Astolfi, Edi Simoni, Filippo Valente, Sara Ghiselli, Stavros Hatzopoulos, Milvia Chicca, Alessandro Martini
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185525 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0162106.].
Externí odkaz:
https://doaj.org/article/fd8bedb4aecb4053b0767eb5fc5aecb2
Autor:
Laura Astolfi, Edi Simoni, Filippo Valente, Sara Ghiselli, Stavros Hatzopoulos, Milvia Chicca, Alessandro Martini
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162106 (2016)
Cisplatin (Cpt) is known to induce a high level of oxidative stress, resulting in an increase of reactive oxygen species damaging the inner ear and causing hearing loss at high frequencies. Studies on animal models show that antioxidants may lower Cp
Externí odkaz:
https://doaj.org/article/2c9d2ed370ed41c594eaff3e4025fa50
Autor:
Roberto P. Revoltella M.D., Ph.D., Sandra Papini, Alfredo Rosellini, Monica Michelini, Valeria Franceschini, Andrea Ciorba, Lucia Bertolaso, Sara Magosso, Stavros Hatzopoulos, Guiscardo Lorito, Pietro Giordano, Edi Simoni, Emanuela Ognio, Michele Cilli, Riccardo Saccardi, Serena Urbani, Rosemary Jeffery, Richard Poulsom, Alessandro Martini
Publikováno v:
Cell Transplantation, Vol 17 (2008)
We investigated the fate of human cord blood CD133+ hematopoietic stem cells (HSC) transplanted intravenously (IV) into irradiated nodscid mice previously made deaf by ototoxic treatment with kanamycin and/or intense noise, to verify whether HSC engr
Externí odkaz:
https://doaj.org/article/bf7bfcdca6cd4ae787771ddaebb36b53