Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Edgardo S. Fortuno"'
Publikováno v:
Annals of Palliative Medicine. 12:600-606
Autor:
Patricia Cho, Bing Cai, Evelyn J. Maan, Monika Esser, Casey P. Shannon, Kinga K. Smolen, Hélène C. F. Côté, Nelly Amenyogbe, William W. Mohn, Tessa Goetghebuer, Candice E. Ruck, Tobias R. Kollmann, Scott Sj Tebbutt, Amy L. Slogrove, Edgardo S. Fortuno, Arnaud Marchant, Pedro A. Dimitriu, Ariane Alimenti
Publikováno v:
J Immunol
The Journal of immunology, 205 (10
The Journal of immunology, 205 (10
In both high-and low-income countries, HIV-negative children born to HIV-positive mothers (HIVexposed, uninfected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) children, with altered innate immunity hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdc95c03ec92a417b5db8d4bfb1e76d
https://europepmc.org/articles/PMC7653510/
https://europepmc.org/articles/PMC7653510/
Autor:
Adeline M Hajjar, Robert K Ernst, Edgardo S Fortuno, Alicia S Brasfield, Cathy S Yam, Lindsay A Newlon, Tobias R Kollmann, Samuel I Miller, Christopher B Wilson
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002963 (2012)
Although lipopolysaccharide (LPS) stimulation through the Toll-like receptor (TLR)-4/MD-2 receptor complex activates host defense against Gram-negative bacterial pathogens, how species-specific differences in LPS recognition impact host defense remai
Externí odkaz:
https://doaj.org/article/2ed58c4147da46e883f07ede1e6adae8
Autor:
Brian A Reikie, Rozanne C M Adams, Candice E Ruck, Kevin Ho, Aleksandra Leligdowicz, Santoshan Pillay, Shalena Naidoo, Edgardo S Fortuno, Corena de Beer, Wolfgang Preiser, Mark F Cotton, David P Speert, Monika Esser, Tobias R Kollmann
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44763 (2012)
The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased risk for infection as well a
Externí odkaz:
https://doaj.org/article/1663c057c8e44cf18262958cdbfa26ae
Autor:
Nathan P Corbett, Darren Blimkie, Kevin C Ho, Bing Cai, Darren P Sutherland, Arlene Kallos, Juliet Crabtree, Annie Rein-Weston, Pascal M Lavoie, Stuart E Turvey, Natalie R Hawkins, Steven G Self, Christopher B Wilson, Adeline M Hajjar, Edgardo S Fortuno, Tobias R Kollmann
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15041 (2010)
Newborns and young infants suffer increased infectious morbidity and mortality as compared to older children and adults. Morbidity and mortality due to infection are highest during the first weeks of life, decreasing over several years. Furthermore,
Externí odkaz:
https://doaj.org/article/f7561129a616468794da1ddc3981c4ab
Autor:
Julie A. Bettinger, Gaston De Serres, Joanne M. Langley, Tobias R. Kollmann, Edgardo S. Fortuno, Patricia Cho, David W. Scheifele, Yan Li, Keswadee Lapphra, Scott A. Halperin, Mona Al-Dabbagh
Publikováno v:
Clinical and Vaccine Immunology. 20:1108-1114
Oculorespiratory syndrome (ORS) is an infrequent adverse event following influenza vaccination. Its clinical presentation suggests that ORS is an immune-mediated phenomenon, but studies of symptomatic individuals have been few. This study measured cy
Autor:
Tobias R. Kollmann, Robert E. W. Hancock, Nathan Corbett, Thierry Lacaze-Masmonteil, Maia Kaplan, Pascal M. Lavoie, Moira Chan-Yeung, Denise Daley, Edgardo S. Fortuno, Nico Marr, Farzian Aminuddin, Andrew J. Sandford, Julia Schneiderman, Salman Ali, Jin Yan, Richard G. Hegele, Loubna Akhabir, Stuart E. Turvey, Shirley Wang, Matthew L. Mayer, Allan B. Becker, Aaron F. Hirschfeld, Christopher D. Fjell
Publikováno v:
The Journal of Immunology. 190:3949-3958
Respiratory diseases are the most frequent chronic illnesses in babies and children. Although a vigorous innate immune system is critical for maintaining lung health, a balanced response is essential to minimize damaging inflammation. We investigated
Autor:
Tobias R. Kollmann, Edgardo S. Fortuno, Allison McDonald, William A. Gahl, Murat Sincan, Rosemarie Rupps, Darren Sutherland, Chidi Ahaghotu, Michelle Demos, Cristina Dias, David P. Speert, Cornelius F. Boerkoel, Ramona Salvarinova, Jan M. Friedman, Rui Santos, Kamal Menghrajani, Thomas C. Markello
Publikováno v:
European Journal of Human Genetics. 21:1232-1239
Inflammation is an important contributor to pediatric and adult neurodegeneration. Understanding the genetic determinants of neuroinflammation provides valuable insight into disease mechanism. We characterize a disorder of recurrent immune-mediated n
Autor:
Kinga K. Smolen, Edgardo S. Fortuno, Tobias R. Kollmann, Laura Gelinas, Lisa Franzen, Mel Krajden, Meena Dawar, Simon Dobson, Gina Ogilvie
Publikováno v:
Vaccine. 30:3572-3579
Vaccination is one of the most effective medical interventions. However, optimization of existing as well as design of new vaccines is still mostly conducted empirically; a rational approach to vaccine design is largely prohibited by the lack of insi
Autor:
Edgardo S. Fortuno, Daniela I.M. Loeffler, Kinga K. Smolen, Darren Blimkie, Tobias R. Kollmann, Brian A. Reikie, Bing Cai
Publikováno v:
Vaccine. 29:83-90
Most existing vaccines do not induce protective immunity immediately following birth, nor do they retain protective efficacy in the latter years of life without booster doses. Using a mouse model, we present evidence that a live-replicating vaccine a