Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Edgardo Alvira"'
Autor:
Dean Messing, Brian S. Hickory, Alan G. Benson, Matthew J. Saabye, Jeff Hitchcock, Heather M. Madsen, Devadas Balekudru, Shaun R. Selness, Richard C. Durley, Laura D. Marrufo, Gary D. Anderson, Li Xing, Kevin D. Jerome, Michael Hepperle, Christie Lance Christopher, Rajesh V. Devraj, Elizabeth G. Webb, Thomas Owen, Ravi G. Kurumbail, Edgardo Alvira, Jeffrey L. Hirsch, Joseph B. Monahan, Paul V. Rucker, Boehm Terri L, Blevis-Bal Radhika M, Huey S. Shieh, John K. Walker, John F. Schindler, Michele A. Promo, Win Naing, Sheri L. Bonar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4059-4065
A series of N-aryl pyridinone inhibitors of p38 mitogen activated protein (MAP) kinase were designed and prepared based on the screening hit SC-25028 (1) and structural comparisons to VX-745 (5). The focus of the investigation targeted the dependence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57328f6e5ea96fc972d684f2e92281c
https://doi.org/10.1016/j.bmcl.2011.04.120
https://doi.org/10.1016/j.bmcl.2011.04.120
Autor:
Kirk R. Gustafson, Lewis K. Pannell, Mark A. Lipton, Sonja Hess, Edgardo Alvira, Dennis J. Milanowski
Publikováno v:
Journal of Chromatography A. 1035:211-219
Unusual amino acids such as beta-methoxytyrosine (beta-MeOTyr), allo-threonine (allo-Thr) and allo-isoleucine (allo-Ile) were derivatized with N-alpha-(2,4-dinitro-5-fluorophenyl)-L-alaninamide (FDAA), 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9da48977c64beed905c311197cdde49
https://doi.org/10.1016/j.chroma.2004.02.068
https://doi.org/10.1016/j.chroma.2004.02.068
Autor:
Susimar González Martínez, Amaris Ferrer, Gabriel Barletta, Edgardo Alvira, Liz Vergara Cordero, Ileana Montañés‐Clemente
Publikováno v:
Biotechnology Progress. 18:1462-1466
Colyophilization with methyl-beta-cyclodextrin activates subtilisin Carlsberg by more than 200-fold in organic solvents, though this is a short-lived effect. About 93% of the enzyme's high initial activity observed in THF (at 45 degrees C) decreases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e47d6ef9ec819f394e2344f124723ae
https://doi.org/10.1021/bp025650g
https://doi.org/10.1021/bp025650g
Autor:
Minedys Macias, Edgardo Alvira, Maricely Fonceca, Ileana Montañez-Clemente, Jessica Rodriguez, Anicele Gonzalez, Amaris Ferrer, Gabriel Barletta
Publikováno v:
Biotechnology and Bioengineering. 78:53-59
In this study we explored the efficiency of the additive methyl-beta-cyclodextrin (M beta CD) to enhance the activity and enantioselectivity of the serine protease subtilisin Carlsberg in organic solvents. These two parameters, measured for different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efafe304b5614f98bd61b80afc918918
https://doi.org/10.1002/bit.10182
https://doi.org/10.1002/bit.10182
Autor:
Ileana, Montañez-Clemente, Edgardo, Alvira, Minedys, Macias, Amaris, Ferrer, Maricely, Fonceca, Jessica, Rodriguez, Anicele, Gonzalez, Gabriel, Barletta
Publikováno v:
Biotechnology and bioengineering. 78(1)
In this study we explored the efficiency of the additive methyl-beta-cyclodextrin (M beta CD) to enhance the activity and enantioselectivity of the serine protease subtilisin Carlsberg in organic solvents. These two parameters, measured for different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::360b8e30452d3fc65521bf3587030cc0
https://pubmed.ncbi.nlm.nih.gov/11857281
https://pubmed.ncbi.nlm.nih.gov/11857281