Zobrazeno 1 - 10
of 2 887
pro vyhledávání: '"Edgar T"'
Autor:
Ashley N. Connelly, Richard P. H. Huijbregts, Harish C. Pal, Valeriya Kuznetsova, Marcus D. Davis, Krystle L. Ong, Christian X. Fay, Morgan E. Greene, Edgar T. Overton, Zdenek Hel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Neutrophils are the most abundant circulating leukocyte population with critical roles in immune defense, regulation of innate and adaptive immune systems, and disease pathogenesis. Our progress in understanding precise mechanisms of neutrop
Externí odkaz:
https://doaj.org/article/6b8d06a67b1c44c3b330ffebdad63b65
Autor:
Emily R. Bowman, Manjusha Kulkarni, Janelle Gabriel, Xiaokui Mo, Brett Klamer, Martha Belury, Jordan E. Lake, David Zidar, Scott F. Sieg, Nehal N. Mehta, Martin P. Playford, Daniel R. Kuritzkes, Adriana Andrade, Elizabeth Koss Schmidt, Christopher Taylor, Edgar T. Overton, Amanda L. Willig, Michael M. Lederman, Nicholas T. Funderburg, the AIDS Clinical Trials Group A5248/A5249s Team
Publikováno v:
Translational Medicine Communications, Vol 5, Iss 1, Pp 1-8 (2020)
Abstract Background Dyslipidemia often accompanies human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART). Lipid abnormalities likely contribute to increased cardiometabolic disease among people with HIV (PWH). Here, we expand
Externí odkaz:
https://doaj.org/article/250d654600bf42a1bafd27e470eeffc5
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 275-290 (2020)
Background: Direct-acting antiviral (DAA) therapy among hepatitis C virus (HCV)-infected kidney transplant recipients is associated with short-term improvement in protein/creatinine (P/C) ratios, but how HCV cure affects long-term graft outcomes rema
Externí odkaz:
https://doaj.org/article/ffe5a9ea026d4ba2ace0fa887044166c
Autor:
Kathleen V. Fitch, Emma M. Kileel, Sara E. Looby, Markella V. Zanni, Laura R. Sanchez, Carl J. Fichtenbaum, Edgar T. Overton, Carlos Malvestutto, Judith A. Aberg, Karin L. Klingman, Beverly Alston-Smith, Judith Lavelle, Anne Rancourt, Sharlaa Badal-Faesen, Sandra Wagner Cardoso, Anchalee Avihingsanon, Sandesh Patil, Craig A. Sponseller, Kathleen Melbourne, Heather J. Ribaudo, Katharine Cooper-Arnold, Patrice Desvigne-Nickens, Udo Hoffmann, Pamela S. Douglas, Steven K. Grinspoon, on behalf of the REPRIEVE Investigators
Publikováno v:
HIV Research & Clinical Practice, Vol 21, Iss 1, Pp 11-23 (2020)
Background: The Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) is a multicenter, randomized, placebo-controlled trial, designed to test whether a statin medication can prevent cardiovascular disease in people with HIV. REPRIEVE recentl
Externí odkaz:
https://doaj.org/article/c1bbcd7120594120b0af18d8c43b3e8f
Autor:
Patrick Deelen, Sipko van Dam, Johanna C. Herkert, Juha M. Karjalainen, Harm Brugge, Kristin M. Abbott, Cleo C. van Diemen, Paul A. van der Zwaag, Erica H. Gerkes, Evelien Zonneveld-Huijssoon, Jelkje J. Boer-Bergsma, Pytrik Folkertsma, Tessa Gillett, K. Joeri van der Velde, Roan Kanninga, Peter C. van den Akker, Sabrina Z. Jan, Edgar T. Hoorntje, Wouter P. te Rijdt, Yvonne J. Vos, Jan D. H. Jongbloed, Conny M. A. van Ravenswaaij-Arts, Richard Sinke, Birgit Sikkema-Raddatz, Wilhelmina S. Kerstjens-Frederikse, Morris A. Swertz, Lude Franke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
A genetic diagnosis remains unattainable for many individuals with a rare disease because of incomplete knowledge about the genetic basis of many diseases. Here, the authors present the web-based tool GADO (GeneNetwork Assisted Diagnostic Optimizatio
Externí odkaz:
https://doaj.org/article/8256eeb26c5746a9a9e8d6dcd1fd68ae
Publikováno v:
Membranes, Vol 12, Iss 4, p 401 (2022)
This work proposes a way to maximize the potential of a Nannochloropsis sp. biorefinery process, through membrane technology, producing an extract enriched in soluble proteins, free from the insoluble protein fraction, with a low lipid content and el
Externí odkaz:
https://doaj.org/article/169db33ea7b34593b1cf2ca95b64a198
Autor:
Lindsay R. Freud, Doff B. McElhinney, Brian T. Kalish, Maria C. Escobar‐Diaz, Rukmini Komarlu, Michael D. Puchalski, Edgar T. Jaeggi, Anita L. Szwast, Grace Freire, Stéphanie M. Levasseur, Ann Kavanaugh‐McHugh, Erik C. Michelfelder, Anita J. Moon‐Grady, Mary T. Donofrio, Lisa W. Howley, Elif Seda Selamet Tierney, Bettina F. Cuneo, Shaine A. Morris, Jay D. Pruetz, Mary E. van der Velde, John P. Kovalchin, Catherine M. Ikemba, Margaret M. Vernon, Cyrus Samai, Gary M. Satou, Nina L. Gotteiner, Colin K. Phoon, Norman H. Silverman, Wayne Tworetzky
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 21 (2020)
Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third of live‐born patients died before hospital discharge. We sought to further describe postnatal manage
Externí odkaz:
https://doaj.org/article/f570055415f34b4584000e7f15fb292a
Autor:
Samantha C. Berkey, Juan J. Herrera, Max A. Odem, Simran Rahman, Sai S. Cheruvu, Xiaodong Cheng, Edgar T. Walters, Carmen W. Dessauer, Alexis G. Bavencoffe
Publikováno v:
Neurobiology of Pain, Vol 7, Iss , Pp - (2020)
Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and k
Externí odkaz:
https://doaj.org/article/0a95a37648694c1290980c12c17cfd1f
Autor:
Michael R. Goetsch, Ashutosh Tamhane, Mohit Varshney, Anuj Kapil, Edgar T. Overton, Graham C. Towns, Ricardo A. Franco
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 366-375 (2017)
Introduction: The role of Hepatitis C Virus (HCV) clearance in long-term kidney graft survival is unknown. In this study, we examined short-term trends of urinary protein/creatinine (P/C) ratios in a cohort of HCV-infected kidney transplant recipient
Externí odkaz:
https://doaj.org/article/05fef48db0df465c9c670675356e6cbd
Autor:
Xia Hu, Morayo G. Adebiyi, Jialie Luo, Kaiqi Sun, Thanh-Thuy T. Le, Yujin Zhang, Hongyu Wu, Shushan Zhao, Harry Karmouty-Quintana, Hong Liu, Aji Huang, Yuan Edward Wen, Oleg L. Zaika, Mykola Mamenko, Oleh M. Pochynyuk, Rodney E. Kellems, Holger K. Eltzschig, Michael R. Blackburn, Edgar T. Walters, Dong Huang, Hongzhen Hu, Yang Xia
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 106-119 (2016)
The molecular mechanisms of chronic pain are poorly understood and effective mechanism-based treatments are lacking. Here, we report that mice lacking adenosine deaminase (ADA), an enzyme necessary for the breakdown of adenosine, displayed unexpected
Externí odkaz:
https://doaj.org/article/5dddea587eed4bdaa8c0847bf03bba97